Osteoimmunology applied to maxillofacial reconstruction

Detalhes bibliográficos
Autor(a) principal: Andrade, Miguel Gustavo Setúbal
Data de Publicação: 2008
Outros Autores: Moreira, David Costa, Reis, Silvia Regina de Almeida, Sadigursky, Moysés
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista odonto ciência (Online)
Texto Completo: https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/2642
Resumo: This literature review aimed to discuss some current aspects related to osteoimmunology applied to maxillofacial reconstruction. Maxillary rehabilitation with implants may demand bone grafting before implant placement in the alveolar ridge. Allografts have been introduced to prevent surgery in a secondary area. Cryopreservation is an important method to decrease tissue antigenicity, but other techniques can also be used such as sterilization by gamma radiation or ethylene oxide. Immunology may participate in the incorporation or rejection process of bone grafts by increasing bone resorption. Several molecules, such as interleukins, receptor activators of nuclear factor κβ ligand RANKL, nuclear factor of activated T cells (NFAT), macrophage-colony stimulating factor (M-CSF), early B cell factor (EBF-2), and osteopontegrin establish the relation between immunological cells and bone graft metabolism. Evidences from the literature suggest that frozen allogenic bone may be a good material for jaw onlay grafts since they do not induce immunological rejection. Key words: Bone graft; allografts; osteoimmunology; osteoclast
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spelling Osteoimmunology applied to maxillofacial reconstructionOsteoimunologia aplicada às reconstruções maxilofaciaisBone graftallograftsosteoimmunologyosteoclastOsteoimmunologyThis literature review aimed to discuss some current aspects related to osteoimmunology applied to maxillofacial reconstruction. Maxillary rehabilitation with implants may demand bone grafting before implant placement in the alveolar ridge. Allografts have been introduced to prevent surgery in a secondary area. Cryopreservation is an important method to decrease tissue antigenicity, but other techniques can also be used such as sterilization by gamma radiation or ethylene oxide. Immunology may participate in the incorporation or rejection process of bone grafts by increasing bone resorption. Several molecules, such as interleukins, receptor activators of nuclear factor κβ ligand RANKL, nuclear factor of activated T cells (NFAT), macrophage-colony stimulating factor (M-CSF), early B cell factor (EBF-2), and osteopontegrin establish the relation between immunological cells and bone graft metabolism. Evidences from the literature suggest that frozen allogenic bone may be a good material for jaw onlay grafts since they do not induce immunological rejection. Key words: Bone graft; allografts; osteoimmunology; osteoclastEsta revisão de literatura teve por objetivo discutir os aspectos atuais da osteoimunologia aplicada às reconstruções maxilofaciais. As reabilitações maxilares por implantes podem demandar enxertia óssea para prévia adequação do rebordo à colocação do implante. Os enxertos ósseos alógenos têm sido introduzidos nesse protocolo para evitar cirurgia numa segunda área. A criopreservação figura como um método importante para diminuir a antigenicidade do tecido, mas outras técnicas podem ser exemplificadas como a esterilização por radiação gama ou óxido de etileno. A imunologia participa do processo de incorporação ou de rejeição dos enxertos ósseos incrementando sua absorção. Diversas moléculas, como as interleucinas, o ligante do receptor ativador do fator nuclear-κβ (RANKL), o fator nuclear de células T ativadas (NFAT), o fator estimulador de colônias de macrófagos (M-CSF), o fator de células B jovens (EBF-2) e a osteoprotegerina estabelecem a relação entre as células imunológicas e o metabolismo do osso enxertado. As evidências obtidas da literatura permitem inferir que o osso alógeno congelado é um bom material para aposição dos maxilares por não induzir rejeição imunológica. Palavras-chave: Enxertos ósseos; enxerto alógeno; osteoimunologia; osteoclastosEDIPUCRS - Editora Universitária da PUCRS2008-06-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Article. Invited Article.info:eu-repo/semantics/otherapplication/pdfhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/2642Revista Odonto Ciência; Vol. 23 No. 2 (2008); 197 - 201Revista Odonto Ciência; v. 23 n. 2 (2008); 197 - 2011980-65230102-9460reponame:Revista odonto ciência (Online)instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSenghttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/2642/3065Andrade, Miguel Gustavo SetúbalMoreira, David CostaReis, Silvia Regina de AlmeidaSadigursky, Moysésinfo:eu-repo/semantics/openAccess2013-11-18T10:48:10Zoai:ojs.revistaseletronicas.pucrs.br:article/2642Revistahttps://revistaseletronicas.pucrs.br/ojs/index.php/foPRIhttps://revistaseletronicas.pucrs.br/ojs/index.php/fo/oai||odontociencia@pucrs.br1980-65230102-9460opendoar:2013-11-18T10:48:10Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false
dc.title.none.fl_str_mv Osteoimmunology applied to maxillofacial reconstruction
Osteoimunologia aplicada às reconstruções maxilofaciais
title Osteoimmunology applied to maxillofacial reconstruction
spellingShingle Osteoimmunology applied to maxillofacial reconstruction
Andrade, Miguel Gustavo Setúbal
Bone graft
allografts
osteoimmunology
osteoclast
Osteoimmunology
title_short Osteoimmunology applied to maxillofacial reconstruction
title_full Osteoimmunology applied to maxillofacial reconstruction
title_fullStr Osteoimmunology applied to maxillofacial reconstruction
title_full_unstemmed Osteoimmunology applied to maxillofacial reconstruction
title_sort Osteoimmunology applied to maxillofacial reconstruction
author Andrade, Miguel Gustavo Setúbal
author_facet Andrade, Miguel Gustavo Setúbal
Moreira, David Costa
Reis, Silvia Regina de Almeida
Sadigursky, Moysés
author_role author
author2 Moreira, David Costa
Reis, Silvia Regina de Almeida
Sadigursky, Moysés
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade, Miguel Gustavo Setúbal
Moreira, David Costa
Reis, Silvia Regina de Almeida
Sadigursky, Moysés
dc.subject.por.fl_str_mv Bone graft
allografts
osteoimmunology
osteoclast
Osteoimmunology
topic Bone graft
allografts
osteoimmunology
osteoclast
Osteoimmunology
description This literature review aimed to discuss some current aspects related to osteoimmunology applied to maxillofacial reconstruction. Maxillary rehabilitation with implants may demand bone grafting before implant placement in the alveolar ridge. Allografts have been introduced to prevent surgery in a secondary area. Cryopreservation is an important method to decrease tissue antigenicity, but other techniques can also be used such as sterilization by gamma radiation or ethylene oxide. Immunology may participate in the incorporation or rejection process of bone grafts by increasing bone resorption. Several molecules, such as interleukins, receptor activators of nuclear factor κβ ligand RANKL, nuclear factor of activated T cells (NFAT), macrophage-colony stimulating factor (M-CSF), early B cell factor (EBF-2), and osteopontegrin establish the relation between immunological cells and bone graft metabolism. Evidences from the literature suggest that frozen allogenic bone may be a good material for jaw onlay grafts since they do not induce immunological rejection. Key words: Bone graft; allografts; osteoimmunology; osteoclast
publishDate 2008
dc.date.none.fl_str_mv 2008-06-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article. Invited Article.
info:eu-repo/semantics/other
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/2642
url https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/2642
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistaseletronicas.pucrs.br/ojs/index.php/fo/article/view/2642/3065
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
publisher.none.fl_str_mv EDIPUCRS - Editora Universitária da PUCRS
dc.source.none.fl_str_mv Revista Odonto Ciência; Vol. 23 No. 2 (2008); 197 - 201
Revista Odonto Ciência; v. 23 n. 2 (2008); 197 - 201
1980-6523
0102-9460
reponame:Revista odonto ciência (Online)
instname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron:PUC_RS
instname_str Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
instacron_str PUC_RS
institution PUC_RS
reponame_str Revista odonto ciência (Online)
collection Revista odonto ciência (Online)
repository.name.fl_str_mv Revista odonto ciência (Online) - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
repository.mail.fl_str_mv ||odontociencia@pucrs.br
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