Protein formulations for emulsions and solid-in-oil dispersions

Detalhes bibliográficos
Autor(a) principal: Martins, Madalena A.
Data de Publicação: 2016
Outros Autores: Loureiro, Ana, Azóia, Nuno G., Silva, C., Cavaco-Paulo, Artur
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/41805
Resumo: Needs from medical and cosmetic areas have led to the design of novel nanosized emulsions and solid-in-oil dispersions of proteins. Here, we describe the production of those emulsions and dispersions using high-energy methodologies such as high-pressure homogenization or ultrasound. Recent work has resulted in new mechanistic insights related to the formation of protein emulsions and dispersions. The production method and composition of these formulations can determine major parameters such as size, stability, and functionality, and therefore their final application. Aqueous nanoemulsions of proteins can be used for drug delivery, while solid-in-oil dispersions are often used in transdermal applications.
id RCAP_03bbabdffb15f6bd59fe97be11790d94
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/41805
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Protein formulations for emulsions and solid-in-oil dispersionsDrug deliveryEmulsionsProteinSolid-in-oil dispersionsTransdermalScience & TechnologyNeeds from medical and cosmetic areas have led to the design of novel nanosized emulsions and solid-in-oil dispersions of proteins. Here, we describe the production of those emulsions and dispersions using high-energy methodologies such as high-pressure homogenization or ultrasound. Recent work has resulted in new mechanistic insights related to the formation of protein emulsions and dispersions. The production method and composition of these formulations can determine major parameters such as size, stability, and functionality, and therefore their final application. Aqueous nanoemulsions of proteins can be used for drug delivery, while solid-in-oil dispersions are often used in transdermal applications.This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684)ElsevierUniversidade do MinhoMartins, Madalena A.Loureiro, AnaAzóia, Nuno G.Silva, C.Cavaco-Paulo, Artur20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/41805eng0167-779910.1016/j.tibtech.2016.03.00126996614info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:14:59Zoai:repositorium.sdum.uminho.pt:1822/41805Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:07:21.311320Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Protein formulations for emulsions and solid-in-oil dispersions
title Protein formulations for emulsions and solid-in-oil dispersions
spellingShingle Protein formulations for emulsions and solid-in-oil dispersions
Martins, Madalena A.
Drug delivery
Emulsions
Protein
Solid-in-oil dispersions
Transdermal
Science & Technology
title_short Protein formulations for emulsions and solid-in-oil dispersions
title_full Protein formulations for emulsions and solid-in-oil dispersions
title_fullStr Protein formulations for emulsions and solid-in-oil dispersions
title_full_unstemmed Protein formulations for emulsions and solid-in-oil dispersions
title_sort Protein formulations for emulsions and solid-in-oil dispersions
author Martins, Madalena A.
author_facet Martins, Madalena A.
Loureiro, Ana
Azóia, Nuno G.
Silva, C.
Cavaco-Paulo, Artur
author_role author
author2 Loureiro, Ana
Azóia, Nuno G.
Silva, C.
Cavaco-Paulo, Artur
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Martins, Madalena A.
Loureiro, Ana
Azóia, Nuno G.
Silva, C.
Cavaco-Paulo, Artur
dc.subject.por.fl_str_mv Drug delivery
Emulsions
Protein
Solid-in-oil dispersions
Transdermal
Science & Technology
topic Drug delivery
Emulsions
Protein
Solid-in-oil dispersions
Transdermal
Science & Technology
description Needs from medical and cosmetic areas have led to the design of novel nanosized emulsions and solid-in-oil dispersions of proteins. Here, we describe the production of those emulsions and dispersions using high-energy methodologies such as high-pressure homogenization or ultrasound. Recent work has resulted in new mechanistic insights related to the formation of protein emulsions and dispersions. The production method and composition of these formulations can determine major parameters such as size, stability, and functionality, and therefore their final application. Aqueous nanoemulsions of proteins can be used for drug delivery, while solid-in-oil dispersions are often used in transdermal applications.
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/41805
url http://hdl.handle.net/1822/41805
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0167-7799
10.1016/j.tibtech.2016.03.001
26996614
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132492316278784

Registros relacionados