Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.16/2492 |
Resumo: | Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits, (ii) to investigate the interaction between both motor and cognitive deficits and (iii) to assess health status as well as treatment outcome of 1000 geriatric inpatients in hospitals of Kiel (Germany), Brescia (Italy), Porto (Portugal), Curitiba (Brazil) and Bochum (Germany). Methods: This is a prospective, explorative observational multi-center study. In addition to the comprehensive geriatric assessment, quantitative measures of reduced mobility and motor and cognitive deficits are performed before and after a two week's inpatient stay. Components of the assessment are mobile technology-based assessments of gait, balance and transfer performance, neuropsychological tests, frailty, sarcopenia, autonomic dysfunction and sensation, and questionnaires to assess behavioral deficits, activities of daily living, quality of life, fear of falling and dysphagia. Structural MRI and an unsupervised 24/7 home assessment of mobility are performed in a subgroup of participants. The study will also investigate the minimal clinically relevant change of the investigated parameters. Discussion: This study will help form a better understanding of symptoms and their complex interactions and treatment effects in a large geriatric cohort. |
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Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-studyBalanceBody-worn sensorsComprehensive geriatric assessmentExecutive functionGaitOlder adultsQuantitative assessmentWearablesBackground: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits, (ii) to investigate the interaction between both motor and cognitive deficits and (iii) to assess health status as well as treatment outcome of 1000 geriatric inpatients in hospitals of Kiel (Germany), Brescia (Italy), Porto (Portugal), Curitiba (Brazil) and Bochum (Germany). Methods: This is a prospective, explorative observational multi-center study. In addition to the comprehensive geriatric assessment, quantitative measures of reduced mobility and motor and cognitive deficits are performed before and after a two week's inpatient stay. Components of the assessment are mobile technology-based assessments of gait, balance and transfer performance, neuropsychological tests, frailty, sarcopenia, autonomic dysfunction and sensation, and questionnaires to assess behavioral deficits, activities of daily living, quality of life, fear of falling and dysphagia. Structural MRI and an unsupervised 24/7 home assessment of mobility are performed in a subgroup of participants. The study will also investigate the minimal clinically relevant change of the investigated parameters. Discussion: This study will help form a better understanding of symptoms and their complex interactions and treatment effects in a large geriatric cohort.BioMed CentralRepositório Científico do Centro Hospitalar Universitário de Santo AntónioGeritz, JohannaMaetzold, SaraSteffen, MarenPilotto, AndreaCorrà, MartaMoscovich, MarianaRizzetti, Maria CBorroni, BarbaraPadovani, AlessandroAlpes, AnnekathrinBang, CorinnaBarcellos, IgorBaron, RalfBartsch, ThorstenBecktepe, Jos SBerg, DanielaBergeest, Lu MBergmann, PhilippBouça-Machado, RaquelDrey, MichaelElshehabi, MoradFarahmandi, SusanFerreira, Joaquim JFranke, AndreFriederich, AnjaGeisler, CorinnaHüllemann, PhilippGierthmühlen, JanneGranert, OliverHeinzel, SebastianHeller, Maren KHobert, Markus AHofmann, MarcJemlich, BjörnKerkmann, LauraKnüpfer, StephanieKrause, KatharinaKress, MaximilianKrupp, SonjaKudelka, JenniferKuhlenbäumer, GregorKurth, RolandLeypoldt, FrankMaetzler, CorinaMaia, LuisMoewius, AndreasNeumann, PatriciaNiemann, KatharinaOrtlieb, Christian TPaschen, SteffenPham, Minh HPuehler, ThomasRadloff, FranziskaRiedel, ChristianRogalski, MartenSablowsky, SimoneSchanz, Elena MSchebesta, LindaSchicketmüller, AndreasStudt, SimoneThieves, MartinaTönges, LarsUllrich, SebastianUrban, Peter PVila-Chã, NunoWiegard, AnnaWarmerdam, ElkeWarnecke, TobiasWeiss, MichaelWelzel, JuliusHansen, ClintMaetzler, Walter2021-07-09T11:05:43Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/2492engGeritz J, Maetzold S, Steffen M, Pilotto A, Corrà MF, Moscovich M, Rizzetti MC, Borroni B, Padovani A, Alpes A, Bang C, Barcellos I, Baron R, Bartsch T, Becktepe JS, Berg D, Bergeest LM, Bergmann P, Bouça-Machado R, Drey M, Elshehabi M, Farahmandi S, Ferreira JJ, Franke A, Friederich A, Geisler C, Hüllemann P, Gierthmühlen J, Granert O, Heinzel S, Heller MK, Hobert MA, Hofmann M, Jemlich B, Kerkmann L, Knüpfer S, Krause K, Kress M, Krupp S, Kudelka J, Kuhlenbäumer G, Kurth R, Leypoldt F, Maetzler C, Maia LF, Moewius A, Neumann P, Niemann K, Ortlieb CT, Paschen S, Pham MH, Puehler T, Radloff F, Riedel C, Rogalski M, Sablowsky S, Schanz EM, Schebesta L, Schicketmüller A, Studt S, Thieves M, Tönges L, Ullrich S, Urban PP, Vila-Chã N, Wiegard A, Warmerdam E, Warnecke T, Weiss M, Welzel J, Hansen C, Maetzler W. Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study. BMC Geriatr. 2020 Feb 6;20(1):45. doi: 10.1186/s12877-020-1445-z. PMID: 32028945; PMCID: PMC7006407.1471-231810.1186/s12877-020-1445-zinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-20T11:00:54Zoai:repositorio.chporto.pt:10400.16/2492Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:38:42.447915Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study |
title |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study |
spellingShingle |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study Geritz, Johanna Balance Body-worn sensors Comprehensive geriatric assessment Executive function Gait Older adults Quantitative assessment Wearables |
title_short |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study |
title_full |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study |
title_fullStr |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study |
title_full_unstemmed |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study |
title_sort |
Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study |
author |
Geritz, Johanna |
author_facet |
Geritz, Johanna Maetzold, Sara Steffen, Maren Pilotto, Andrea Corrà, Marta Moscovich, Mariana Rizzetti, Maria C Borroni, Barbara Padovani, Alessandro Alpes, Annekathrin Bang, Corinna Barcellos, Igor Baron, Ralf Bartsch, Thorsten Becktepe, Jos S Berg, Daniela Bergeest, Lu M Bergmann, Philipp Bouça-Machado, Raquel Drey, Michael Elshehabi, Morad Farahmandi, Susan Ferreira, Joaquim J Franke, Andre Friederich, Anja Geisler, Corinna Hüllemann, Philipp Gierthmühlen, Janne Granert, Oliver Heinzel, Sebastian Heller, Maren K Hobert, Markus A Hofmann, Marc Jemlich, Björn Kerkmann, Laura Knüpfer, Stephanie Krause, Katharina Kress, Maximilian Krupp, Sonja Kudelka, Jennifer Kuhlenbäumer, Gregor Kurth, Roland Leypoldt, Frank Maetzler, Corina Maia, Luis Moewius, Andreas Neumann, Patricia Niemann, Katharina Ortlieb, Christian T Paschen, Steffen Pham, Minh H Puehler, Thomas Radloff, Franziska Riedel, Christian Rogalski, Marten Sablowsky, Simone Schanz, Elena M Schebesta, Linda Schicketmüller, Andreas Studt, Simone Thieves, Martina Tönges, Lars Ullrich, Sebastian Urban, Peter P Vila-Chã, Nuno Wiegard, Anna Warmerdam, Elke Warnecke, Tobias Weiss, Michael Welzel, Julius Hansen, Clint Maetzler, Walter |
author_role |
author |
author2 |
Maetzold, Sara Steffen, Maren Pilotto, Andrea Corrà, Marta Moscovich, Mariana Rizzetti, Maria C Borroni, Barbara Padovani, Alessandro Alpes, Annekathrin Bang, Corinna Barcellos, Igor Baron, Ralf Bartsch, Thorsten Becktepe, Jos S Berg, Daniela Bergeest, Lu M Bergmann, Philipp Bouça-Machado, Raquel Drey, Michael Elshehabi, Morad Farahmandi, Susan Ferreira, Joaquim J Franke, Andre Friederich, Anja Geisler, Corinna Hüllemann, Philipp Gierthmühlen, Janne Granert, Oliver Heinzel, Sebastian Heller, Maren K Hobert, Markus A Hofmann, Marc Jemlich, Björn Kerkmann, Laura Knüpfer, Stephanie Krause, Katharina Kress, Maximilian Krupp, Sonja Kudelka, Jennifer Kuhlenbäumer, Gregor Kurth, Roland Leypoldt, Frank Maetzler, Corina Maia, Luis Moewius, Andreas Neumann, Patricia Niemann, Katharina Ortlieb, Christian T Paschen, Steffen Pham, Minh H Puehler, Thomas Radloff, Franziska Riedel, Christian Rogalski, Marten Sablowsky, Simone Schanz, Elena M Schebesta, Linda Schicketmüller, Andreas Studt, Simone Thieves, Martina Tönges, Lars Ullrich, Sebastian Urban, Peter P Vila-Chã, Nuno Wiegard, Anna Warmerdam, Elke Warnecke, Tobias Weiss, Michael Welzel, Julius Hansen, Clint Maetzler, Walter |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Centro Hospitalar Universitário de Santo António |
dc.contributor.author.fl_str_mv |
Geritz, Johanna Maetzold, Sara Steffen, Maren Pilotto, Andrea Corrà, Marta Moscovich, Mariana Rizzetti, Maria C Borroni, Barbara Padovani, Alessandro Alpes, Annekathrin Bang, Corinna Barcellos, Igor Baron, Ralf Bartsch, Thorsten Becktepe, Jos S Berg, Daniela Bergeest, Lu M Bergmann, Philipp Bouça-Machado, Raquel Drey, Michael Elshehabi, Morad Farahmandi, Susan Ferreira, Joaquim J Franke, Andre Friederich, Anja Geisler, Corinna Hüllemann, Philipp Gierthmühlen, Janne Granert, Oliver Heinzel, Sebastian Heller, Maren K Hobert, Markus A Hofmann, Marc Jemlich, Björn Kerkmann, Laura Knüpfer, Stephanie Krause, Katharina Kress, Maximilian Krupp, Sonja Kudelka, Jennifer Kuhlenbäumer, Gregor Kurth, Roland Leypoldt, Frank Maetzler, Corina Maia, Luis Moewius, Andreas Neumann, Patricia Niemann, Katharina Ortlieb, Christian T Paschen, Steffen Pham, Minh H Puehler, Thomas Radloff, Franziska Riedel, Christian Rogalski, Marten Sablowsky, Simone Schanz, Elena M Schebesta, Linda Schicketmüller, Andreas Studt, Simone Thieves, Martina Tönges, Lars Ullrich, Sebastian Urban, Peter P Vila-Chã, Nuno Wiegard, Anna Warmerdam, Elke Warnecke, Tobias Weiss, Michael Welzel, Julius Hansen, Clint Maetzler, Walter |
dc.subject.por.fl_str_mv |
Balance Body-worn sensors Comprehensive geriatric assessment Executive function Gait Older adults Quantitative assessment Wearables |
topic |
Balance Body-worn sensors Comprehensive geriatric assessment Executive function Gait Older adults Quantitative assessment Wearables |
description |
Background: Motor and cognitive deficits and consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis and for the evaluation of treatment in this vulnerable cohort are limited. The aims of the ComOn (COgnitive and Motor interactions in the Older populatioN) study are (i) to define quantitative markers with clinical relevance for motor and cognitive deficits, (ii) to investigate the interaction between both motor and cognitive deficits and (iii) to assess health status as well as treatment outcome of 1000 geriatric inpatients in hospitals of Kiel (Germany), Brescia (Italy), Porto (Portugal), Curitiba (Brazil) and Bochum (Germany). Methods: This is a prospective, explorative observational multi-center study. In addition to the comprehensive geriatric assessment, quantitative measures of reduced mobility and motor and cognitive deficits are performed before and after a two week's inpatient stay. Components of the assessment are mobile technology-based assessments of gait, balance and transfer performance, neuropsychological tests, frailty, sarcopenia, autonomic dysfunction and sensation, and questionnaires to assess behavioral deficits, activities of daily living, quality of life, fear of falling and dysphagia. Structural MRI and an unsupervised 24/7 home assessment of mobility are performed in a subgroup of participants. The study will also investigate the minimal clinically relevant change of the investigated parameters. Discussion: This study will help form a better understanding of symptoms and their complex interactions and treatment effects in a large geriatric cohort. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z 2021-07-09T11:05:43Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.16/2492 |
url |
http://hdl.handle.net/10400.16/2492 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Geritz J, Maetzold S, Steffen M, Pilotto A, Corrà MF, Moscovich M, Rizzetti MC, Borroni B, Padovani A, Alpes A, Bang C, Barcellos I, Baron R, Bartsch T, Becktepe JS, Berg D, Bergeest LM, Bergmann P, Bouça-Machado R, Drey M, Elshehabi M, Farahmandi S, Ferreira JJ, Franke A, Friederich A, Geisler C, Hüllemann P, Gierthmühlen J, Granert O, Heinzel S, Heller MK, Hobert MA, Hofmann M, Jemlich B, Kerkmann L, Knüpfer S, Krause K, Kress M, Krupp S, Kudelka J, Kuhlenbäumer G, Kurth R, Leypoldt F, Maetzler C, Maia LF, Moewius A, Neumann P, Niemann K, Ortlieb CT, Paschen S, Pham MH, Puehler T, Radloff F, Riedel C, Rogalski M, Sablowsky S, Schanz EM, Schebesta L, Schicketmüller A, Studt S, Thieves M, Tönges L, Ullrich S, Urban PP, Vila-Chã N, Wiegard A, Warmerdam E, Warnecke T, Weiss M, Welzel J, Hansen C, Maetzler W. Motor, cognitive and mobility deficits in 1000 geriatric patients: protocol of a quantitative observational study before and after routine clinical geriatric treatment - the ComOn-study. BMC Geriatr. 2020 Feb 6;20(1):45. doi: 10.1186/s12877-020-1445-z. PMID: 32028945; PMCID: PMC7006407. 1471-2318 10.1186/s12877-020-1445-z |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central |
publisher.none.fl_str_mv |
BioMed Central |
dc.source.none.fl_str_mv |
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