Cardiac Angiosarcoma. A Review
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/623 |
Resumo: | Based on a case of a patient with angiosarcoma (AS) of the right atrium with superior vena cava syndrome associated with urticaria and polyarthralgias, who died soon after surgery, the authors present a brief review of the subject of cardiac AS, an extremely rare pathology, usually diagnosed late due to its non-specific symptomatology. Several topics are discussed, including mechanisms of clinical manifestations caused by blood flow obstruction and valve dysfunction, local invasion with arrhythmias and pericardial effusion, embolic phenomena and constitutional symptoms. Imaging and histopathologic methods of diagnosis are considered, as well as references to cytogenetic analysis. Surgery is the first treatment choice, but heart AS are frequently not completely resectable and concomitant metastases at the time of surgery are common, both usually leading to a dismal prognosis. Chemotherapy, radiotherapy and even heart transplantation do not substantially improve the survival of these patients. Urticaria is not generally assumed by most authors to be associated with malignancy, but there are rare reports of its association with some malignant tumors. |
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Cardiac Angiosarcoma. A ReviewAngiosarcoma Cardíaco. Uma RevisãoNeoplasias CardíacasAngiosarcomaHCC MEDHCC DERHSM CARHSM CCTHSM ANPATBased on a case of a patient with angiosarcoma (AS) of the right atrium with superior vena cava syndrome associated with urticaria and polyarthralgias, who died soon after surgery, the authors present a brief review of the subject of cardiac AS, an extremely rare pathology, usually diagnosed late due to its non-specific symptomatology. Several topics are discussed, including mechanisms of clinical manifestations caused by blood flow obstruction and valve dysfunction, local invasion with arrhythmias and pericardial effusion, embolic phenomena and constitutional symptoms. Imaging and histopathologic methods of diagnosis are considered, as well as references to cytogenetic analysis. Surgery is the first treatment choice, but heart AS are frequently not completely resectable and concomitant metastases at the time of surgery are common, both usually leading to a dismal prognosis. Chemotherapy, radiotherapy and even heart transplantation do not substantially improve the survival of these patients. Urticaria is not generally assumed by most authors to be associated with malignancy, but there are rare reports of its association with some malignant tumors.Sociedade Portuguesa de CardiologiaRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEMurinello, AMendonça, PAbreu, ASantos, ALRoquette, JPinto, EAlpendra, JSemedo, JRodrigues, ACunha, DCoelho, JFLourenço, SMiranda, S2012-08-17T15:23:56Z20072007-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/623engRev Port Cardiol. 2007 May;26(5):577-84info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:27:26ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Cardiac Angiosarcoma. A Review Angiosarcoma Cardíaco. Uma Revisão |
title |
Cardiac Angiosarcoma. A Review |
spellingShingle |
Cardiac Angiosarcoma. A Review Murinello, A Neoplasias Cardíacas Angiosarcoma HCC MED HCC DER HSM CAR HSM CCT HSM ANPAT |
title_short |
Cardiac Angiosarcoma. A Review |
title_full |
Cardiac Angiosarcoma. A Review |
title_fullStr |
Cardiac Angiosarcoma. A Review |
title_full_unstemmed |
Cardiac Angiosarcoma. A Review |
title_sort |
Cardiac Angiosarcoma. A Review |
author |
Murinello, A |
author_facet |
Murinello, A Mendonça, P Abreu, A Santos, AL Roquette, J Pinto, E Alpendra, J Semedo, J Rodrigues, A Cunha, D Coelho, JF Lourenço, S Miranda, S |
author_role |
author |
author2 |
Mendonça, P Abreu, A Santos, AL Roquette, J Pinto, E Alpendra, J Semedo, J Rodrigues, A Cunha, D Coelho, JF Lourenço, S Miranda, S |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Murinello, A Mendonça, P Abreu, A Santos, AL Roquette, J Pinto, E Alpendra, J Semedo, J Rodrigues, A Cunha, D Coelho, JF Lourenço, S Miranda, S |
dc.subject.por.fl_str_mv |
Neoplasias Cardíacas Angiosarcoma HCC MED HCC DER HSM CAR HSM CCT HSM ANPAT |
topic |
Neoplasias Cardíacas Angiosarcoma HCC MED HCC DER HSM CAR HSM CCT HSM ANPAT |
description |
Based on a case of a patient with angiosarcoma (AS) of the right atrium with superior vena cava syndrome associated with urticaria and polyarthralgias, who died soon after surgery, the authors present a brief review of the subject of cardiac AS, an extremely rare pathology, usually diagnosed late due to its non-specific symptomatology. Several topics are discussed, including mechanisms of clinical manifestations caused by blood flow obstruction and valve dysfunction, local invasion with arrhythmias and pericardial effusion, embolic phenomena and constitutional symptoms. Imaging and histopathologic methods of diagnosis are considered, as well as references to cytogenetic analysis. Surgery is the first treatment choice, but heart AS are frequently not completely resectable and concomitant metastases at the time of surgery are common, both usually leading to a dismal prognosis. Chemotherapy, radiotherapy and even heart transplantation do not substantially improve the survival of these patients. Urticaria is not generally assumed by most authors to be associated with malignancy, but there are rare reports of its association with some malignant tumors. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007 2007-01-01T00:00:00Z 2012-08-17T15:23:56Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/623 |
url |
http://hdl.handle.net/10400.17/623 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Rev Port Cardiol. 2007 May;26(5):577-84 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Cardiologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Cardiologia |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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1777302261330870272 |