A benign cause of hyperandrogenism in a postmenopausal woman

Detalhes bibliográficos
Autor(a) principal: Roque, João José Nunes
Data de Publicação: 2021
Outros Autores: Alves, Irina Borisovna Samokhvalova, Rodrigues, Ana Maria, Bugalho, Maria João
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/46533
Resumo: © 2021 The authors. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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spelling A benign cause of hyperandrogenism in a postmenopausal woman© 2021 The authors. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.Summary: Menopause is a relative hyperandrogenic state but the development of hirsutism or virilizing features should not be regarded as normal. We report the case of a 62-year-old woman with a 9-month history of progressive frontotemporal hair loss and hirsutism, particularly on her back, arms and forearms. Blood tests showed increased total testosterone of 5.20 nmol/L that remained elevated after an overnight dexamethasone suppression test. Free Androgen Index was 13.1 and DHEAS was repeatedly normal. Imaging examinations to study adrenals and ovaries were negative. The biochemical profile and the absence of imaging in favor of an adrenal tumor made us consider the ovarian origin as the most likely hypothesis. After informed consent, bilateral salpingectomy-oophorectomy and total hysterectomy were performed. Gross pathology revealed ovaries of increased volume and histology showed bilateral ovarian stromal hyperplasia. Testosterone levels normalized after surgery and hirsutism had completely subsided 8 months later.Bioscientifica Ltd.Repositório da Universidade de LisboaRoque, João José NunesAlves, Irina Borisovna SamokhvalovaRodrigues, Ana MariaBugalho, Maria João2021-02-25T17:55:39Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/46533engEndocrinol Diabetes Metab Case Rep. 2021 Feb 17;2021:EDM200054.10.1530/EDM-20-00542052-0573info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:48:53Zoai:repositorio.ul.pt:10451/46533Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:58:41.984006Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A benign cause of hyperandrogenism in a postmenopausal woman
title A benign cause of hyperandrogenism in a postmenopausal woman
spellingShingle A benign cause of hyperandrogenism in a postmenopausal woman
Roque, João José Nunes
title_short A benign cause of hyperandrogenism in a postmenopausal woman
title_full A benign cause of hyperandrogenism in a postmenopausal woman
title_fullStr A benign cause of hyperandrogenism in a postmenopausal woman
title_full_unstemmed A benign cause of hyperandrogenism in a postmenopausal woman
title_sort A benign cause of hyperandrogenism in a postmenopausal woman
author Roque, João José Nunes
author_facet Roque, João José Nunes
Alves, Irina Borisovna Samokhvalova
Rodrigues, Ana Maria
Bugalho, Maria João
author_role author
author2 Alves, Irina Borisovna Samokhvalova
Rodrigues, Ana Maria
Bugalho, Maria João
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Roque, João José Nunes
Alves, Irina Borisovna Samokhvalova
Rodrigues, Ana Maria
Bugalho, Maria João
description © 2021 The authors. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
publishDate 2021
dc.date.none.fl_str_mv 2021-02-25T17:55:39Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/46533
url http://hdl.handle.net/10451/46533
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Endocrinol Diabetes Metab Case Rep. 2021 Feb 17;2021:EDM200054.
10.1530/EDM-20-0054
2052-0573
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Bioscientifica Ltd.
publisher.none.fl_str_mv Bioscientifica Ltd.
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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