Adverse drug reactions in hospitals

Detalhes bibliográficos
Autor(a) principal: Ascenção, Raquel
Data de Publicação: 2023
Outros Autores: Nogueira, Paulo, Sampaio, Filipa, Henriques, Adriana, Costa, Andreia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/160408
Resumo: Funding Information: This work was produced with the computational support of INCD – Instituto Nacional de Computação Distribuida – which is funded by Fundação para a Ciência e Tecnologia and FEDER under project 01/SAICT/2016 No. 022153. The authors would like to thank the Portuguese Central Administration of the Health System, I.P. (ACSS) for providing access to the data from the Portuguese Hospital Morbidity Database. Funding Information: This publication was supported by Funds from Fundação para a Ciência e Tecnologia to the Instituto de Saúde Ambiental, Faculdade de Medicina, Universidade de Lisboa (UIDB/04295/2020). Funding Information: This work was produced with the computational support of INCD – Instituto Nacional de Computação Distribuida – which is funded by Fundação para a Ciência e Tecnologia and FEDER under project 01/SAICT/2016 No. 022153. Publisher Copyright: © 2023, The Author(s).
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spelling Adverse drug reactions in hospitalspopulation estimates for Portugal and the ICD-9-CM to ICD-10-CM crosswalkDrug-related side effects and adverse reactionsHospital information systemsInternational classification of diseasesMedical errorsPoisoningPortugalHealth PolicySDG 3 - Good Health and Well-beingFunding Information: This work was produced with the computational support of INCD – Instituto Nacional de Computação Distribuida – which is funded by Fundação para a Ciência e Tecnologia and FEDER under project 01/SAICT/2016 No. 022153. The authors would like to thank the Portuguese Central Administration of the Health System, I.P. (ACSS) for providing access to the data from the Portuguese Hospital Morbidity Database. Funding Information: This publication was supported by Funds from Fundação para a Ciência e Tecnologia to the Instituto de Saúde Ambiental, Faculdade de Medicina, Universidade de Lisboa (UIDB/04295/2020). Funding Information: This work was produced with the computational support of INCD – Instituto Nacional de Computação Distribuida – which is funded by Fundação para a Ciência e Tecnologia and FEDER under project 01/SAICT/2016 No. 022153. Publisher Copyright: © 2023, The Author(s).Background: Adverse drug reactions (ADR), both preventable and non-preventable, are frequent and pose a significant burden. This study aimed to produce up-to-date estimates for ADR rates in hospitals, in Portugal, from 2010 to 2018. In addition, it explores possible pitfalls when crosswalking between ICD-9-CM and ICD-10-CM code sets for ADR identification. Methods: The Portuguese Hospital Morbidity Database was used to identify hospital episodes (outpatient or inpatient) with at least one ICD code of ADR. Since the study period spanned from 2010 to 2018, both ICD-9-CM and ICD-10-CM codes based on previously published studies were used to define episodes. This was an exploratory study, and descriptive statistics were used to provide ADR rates and summarise episode features for the full period (2010–2018) as well as for the ICD-9-CM (2010–2016) and ICD -10-CM (2017–2018) eras. Results: Between 2010 and 2018, ADR occurred in 162,985 hospital episodes, corresponding to 1.00% of the total number of episodes during the same period. Higher rates were seen in the oldest age groups. In the same period, the mean annual rate of episodes related to ADR was 174.2/100,000 population. The episode rate (per 100,000 population) was generally higher in males, except in young adults (aged '15–20', '25–30' and '30–35' years), although the overall frequency of ADR in hospital episodes was higher in females. Conclusions: Despite the ICD-10-CM transition, administrative health data in Portugal remain a feasible source for producing up-to-date estimates on ADR in hospitals. There is a need for future research to identify target recipients for preventive interventions and improve medication safety practices in Portugal.Escola Nacional de Saúde Pública (ENSP)Comprehensive Health Research Centre (CHRC) - Pólo ENSPCentro de Investigação em Saúde Pública (CISP/PHRC)RUNAscenção, RaquelNogueira, PauloSampaio, FilipaHenriques, AdrianaCosta, Andreia2023-11-23T23:21:03Z2023-122023-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/160408eng1472-6963PURE: 76920059https://doi.org/10.1186/s12913-023-10225-zinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:43:06Zoai:run.unl.pt:10362/160408Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:58:01.571025Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Adverse drug reactions in hospitals
population estimates for Portugal and the ICD-9-CM to ICD-10-CM crosswalk
title Adverse drug reactions in hospitals
spellingShingle Adverse drug reactions in hospitals
Ascenção, Raquel
Drug-related side effects and adverse reactions
Hospital information systems
International classification of diseases
Medical errors
Poisoning
Portugal
Health Policy
SDG 3 - Good Health and Well-being
title_short Adverse drug reactions in hospitals
title_full Adverse drug reactions in hospitals
title_fullStr Adverse drug reactions in hospitals
title_full_unstemmed Adverse drug reactions in hospitals
title_sort Adverse drug reactions in hospitals
author Ascenção, Raquel
author_facet Ascenção, Raquel
Nogueira, Paulo
Sampaio, Filipa
Henriques, Adriana
Costa, Andreia
author_role author
author2 Nogueira, Paulo
Sampaio, Filipa
Henriques, Adriana
Costa, Andreia
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Escola Nacional de Saúde Pública (ENSP)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Centro de Investigação em Saúde Pública (CISP/PHRC)
RUN
dc.contributor.author.fl_str_mv Ascenção, Raquel
Nogueira, Paulo
Sampaio, Filipa
Henriques, Adriana
Costa, Andreia
dc.subject.por.fl_str_mv Drug-related side effects and adverse reactions
Hospital information systems
International classification of diseases
Medical errors
Poisoning
Portugal
Health Policy
SDG 3 - Good Health and Well-being
topic Drug-related side effects and adverse reactions
Hospital information systems
International classification of diseases
Medical errors
Poisoning
Portugal
Health Policy
SDG 3 - Good Health and Well-being
description Funding Information: This work was produced with the computational support of INCD – Instituto Nacional de Computação Distribuida – which is funded by Fundação para a Ciência e Tecnologia and FEDER under project 01/SAICT/2016 No. 022153. The authors would like to thank the Portuguese Central Administration of the Health System, I.P. (ACSS) for providing access to the data from the Portuguese Hospital Morbidity Database. Funding Information: This publication was supported by Funds from Fundação para a Ciência e Tecnologia to the Instituto de Saúde Ambiental, Faculdade de Medicina, Universidade de Lisboa (UIDB/04295/2020). Funding Information: This work was produced with the computational support of INCD – Instituto Nacional de Computação Distribuida – which is funded by Fundação para a Ciência e Tecnologia and FEDER under project 01/SAICT/2016 No. 022153. Publisher Copyright: © 2023, The Author(s).
publishDate 2023
dc.date.none.fl_str_mv 2023-11-23T23:21:03Z
2023-12
2023-12-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/160408
url http://hdl.handle.net/10362/160408
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1472-6963
PURE: 76920059
https://doi.org/10.1186/s12913-023-10225-z
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
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instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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