Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/22485 |
Resumo: | Occupational exposure as a firefighter has recently been classified as a carcinogen to humans by International Agency for Research on Cancer (IARC). Biomonitoring has been increasingly used to characterize exposure of firefighting forces to contaminants. However, available data are dispersed and information on the most relevant and promising biomarkers in this context of firefighting is missing. This review presents a comprehensive summary and critical appraisal of existing biomar-kers of exposure including volatile organic compounds such as polycyclic aromatic hydrocarbons, several other persistent other organic pollutants as well as heavy metals and metalloids detected in biological fluids of firefighters attending different fire scenarios. Urine was the most characterized matrix, followed by blood. Firefighters exhaled breath and saliva were poorly evaluated. Overall, biological levels of compounds were predominantly increased in firefighters after participation in firefighting activities. Biomonitoring studies combining different biomarkers of exposure and of effect are currently limited but exploratory findings are of high interest. However, biomonitoring still has some unresolved major limitations since reference or recommended values are not yet established for most biomarkers. In addition, half-lives values for most of the biomarkers have thus far not been defined, which significantly hampers the design of studies. These limitations need to be tackled urgently to improve risk assessment and support implementation of better more effective preventive strategies. |
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Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from firesOccupational exposureHuman biomonitoringFirefightersFire emissionsBiomarkers of exposureHealth risksOccupational exposure as a firefighter has recently been classified as a carcinogen to humans by International Agency for Research on Cancer (IARC). Biomonitoring has been increasingly used to characterize exposure of firefighting forces to contaminants. However, available data are dispersed and information on the most relevant and promising biomarkers in this context of firefighting is missing. This review presents a comprehensive summary and critical appraisal of existing biomar-kers of exposure including volatile organic compounds such as polycyclic aromatic hydrocarbons, several other persistent other organic pollutants as well as heavy metals and metalloids detected in biological fluids of firefighters attending different fire scenarios. Urine was the most characterized matrix, followed by blood. Firefighters exhaled breath and saliva were poorly evaluated. Overall, biological levels of compounds were predominantly increased in firefighters after participation in firefighting activities. Biomonitoring studies combining different biomarkers of exposure and of effect are currently limited but exploratory findings are of high interest. However, biomonitoring still has some unresolved major limitations since reference or recommended values are not yet established for most biomarkers. In addition, half-lives values for most of the biomarkers have thus far not been defined, which significantly hampers the design of studies. These limitations need to be tackled urgently to improve risk assessment and support implementation of better more effective preventive strategies.This work received support by UIDB/50006/2020, UIDP/ 50006/2020, LA/P/0008/2020, and through the project PCIF/ SSO/0090/2019 by the Fundação para a Ciência e a Tecnologia (FCT), Ministério da Ciência, Tecnologia e Ensino Superior (MCTES) through national funds. The authors would also like to thank to FCT and European Union through Fundo Social Europeu (FSE) which supported the scientific contract CEEC- Individual 2017 Program Contract CEECIND/03666/2017 and the PhD grant 2020.07394.BD, respectively.Taylor & Francis OnlineRepositório Científico do Instituto Politécnico do PortoBarros, BelaOliveira, MartaMorais, Simone2023-03-14T12:27:00Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/22485engBela Barros, Marta Oliveira & Simone Morais (2023): Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires, Journal of Toxicology and Environmental Health, Part B, DOI: 10.1080/10937404.2023.217211910.1080/10937404.2023.2172119info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-22T01:46:51Zoai:recipp.ipp.pt:10400.22/22485Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:42:34.038592Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires |
title |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires |
spellingShingle |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires Barros, Bela Occupational exposure Human biomonitoring Firefighters Fire emissions Biomarkers of exposure Health risks |
title_short |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires |
title_full |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires |
title_fullStr |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires |
title_full_unstemmed |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires |
title_sort |
Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires |
author |
Barros, Bela |
author_facet |
Barros, Bela Oliveira, Marta Morais, Simone |
author_role |
author |
author2 |
Oliveira, Marta Morais, Simone |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
Barros, Bela Oliveira, Marta Morais, Simone |
dc.subject.por.fl_str_mv |
Occupational exposure Human biomonitoring Firefighters Fire emissions Biomarkers of exposure Health risks |
topic |
Occupational exposure Human biomonitoring Firefighters Fire emissions Biomarkers of exposure Health risks |
description |
Occupational exposure as a firefighter has recently been classified as a carcinogen to humans by International Agency for Research on Cancer (IARC). Biomonitoring has been increasingly used to characterize exposure of firefighting forces to contaminants. However, available data are dispersed and information on the most relevant and promising biomarkers in this context of firefighting is missing. This review presents a comprehensive summary and critical appraisal of existing biomar-kers of exposure including volatile organic compounds such as polycyclic aromatic hydrocarbons, several other persistent other organic pollutants as well as heavy metals and metalloids detected in biological fluids of firefighters attending different fire scenarios. Urine was the most characterized matrix, followed by blood. Firefighters exhaled breath and saliva were poorly evaluated. Overall, biological levels of compounds were predominantly increased in firefighters after participation in firefighting activities. Biomonitoring studies combining different biomarkers of exposure and of effect are currently limited but exploratory findings are of high interest. However, biomonitoring still has some unresolved major limitations since reference or recommended values are not yet established for most biomarkers. In addition, half-lives values for most of the biomarkers have thus far not been defined, which significantly hampers the design of studies. These limitations need to be tackled urgently to improve risk assessment and support implementation of better more effective preventive strategies. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-03-14T12:27:00Z 2023 2023-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/22485 |
url |
http://hdl.handle.net/10400.22/22485 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Bela Barros, Marta Oliveira & Simone Morais (2023): Biomonitoring of firefighting forces: a review on biomarkers of exposure to health-relevant pollutants released from fires, Journal of Toxicology and Environmental Health, Part B, DOI: 10.1080/10937404.2023.2172119 10.1080/10937404.2023.2172119 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Taylor & Francis Online |
publisher.none.fl_str_mv |
Taylor & Francis Online |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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