Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/2615 |
Resumo: | The efficacy and safety of oral misoprostol for labor induction of twins is unknown. We conducted a retrospective case-control study to evaluate the use of oral misoprostol in near term (> or =35 weeks) twin pregnancies in nulliparas. Eligible cases were given 100 mcg oral misoprostol, which was repeated after 6 h if labor did not start. Either a third dose or diluted oxytocin infusion were given in intractable cases. Diluted oxytocin infusion was used for augmentation. Controls were nulliparas delivered at > or =35 weeks by elective cesarean section. The two groups were comparable in most aspects, except for fetal malpresentation, which was the major reason for avoiding induction. Of the 69 patients in whom labor was induced, 53 (76.8%) had a vaginal birth, 3 (4.3%) had a combined twin delivery, and 13 (18.8%) had a cesarean during labor. The mean length of stay of the neonates was significantly shorter among study cases, without significant difference in the frequency of delayed discharges as an overall proxy for neonatal complications. Labor induction with oral misoprostol could be offered to patients in whom near term vaginal twin delivery is unequivocally permitted and wish to deliver by the vaginal route. |
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Induction of Labor with Oral Misoprostol in Nulliparous Mothers of TwinsAdministration, OralCase-Control StudiesCesarean SectionDelivery, ObstetricFemaleHumansLabor, InducedMisoprostolOxytocicsParityPregnancyRetrospective StudiesTwinsMAC MED MAFThe efficacy and safety of oral misoprostol for labor induction of twins is unknown. We conducted a retrospective case-control study to evaluate the use of oral misoprostol in near term (> or =35 weeks) twin pregnancies in nulliparas. Eligible cases were given 100 mcg oral misoprostol, which was repeated after 6 h if labor did not start. Either a third dose or diluted oxytocin infusion were given in intractable cases. Diluted oxytocin infusion was used for augmentation. Controls were nulliparas delivered at > or =35 weeks by elective cesarean section. The two groups were comparable in most aspects, except for fetal malpresentation, which was the major reason for avoiding induction. Of the 69 patients in whom labor was induced, 53 (76.8%) had a vaginal birth, 3 (4.3%) had a combined twin delivery, and 13 (18.8%) had a cesarean during labor. The mean length of stay of the neonates was significantly shorter among study cases, without significant difference in the frequency of delayed discharges as an overall proxy for neonatal complications. Labor induction with oral misoprostol could be offered to patients in whom near term vaginal twin delivery is unequivocally permitted and wish to deliver by the vaginal route.De GruyterRepositório do Centro Hospitalar Universitário de Lisboa Central, EPESimões, TCondeço, PDias, EVentura, PMatos, CBlickstein, I2017-01-11T15:48:59Z20062006-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2615engJ Perinat Med. 2006;34(2):111-4.10.1515/JPM.2006.020info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:38:42ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins |
title |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins |
spellingShingle |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins Simões, T Administration, Oral Case-Control Studies Cesarean Section Delivery, Obstetric Female Humans Labor, Induced Misoprostol Oxytocics Parity Pregnancy Retrospective Studies Twins MAC MED MAF |
title_short |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins |
title_full |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins |
title_fullStr |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins |
title_full_unstemmed |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins |
title_sort |
Induction of Labor with Oral Misoprostol in Nulliparous Mothers of Twins |
author |
Simões, T |
author_facet |
Simões, T Condeço, P Dias, E Ventura, P Matos, C Blickstein, I |
author_role |
author |
author2 |
Condeço, P Dias, E Ventura, P Matos, C Blickstein, I |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Simões, T Condeço, P Dias, E Ventura, P Matos, C Blickstein, I |
dc.subject.por.fl_str_mv |
Administration, Oral Case-Control Studies Cesarean Section Delivery, Obstetric Female Humans Labor, Induced Misoprostol Oxytocics Parity Pregnancy Retrospective Studies Twins MAC MED MAF |
topic |
Administration, Oral Case-Control Studies Cesarean Section Delivery, Obstetric Female Humans Labor, Induced Misoprostol Oxytocics Parity Pregnancy Retrospective Studies Twins MAC MED MAF |
description |
The efficacy and safety of oral misoprostol for labor induction of twins is unknown. We conducted a retrospective case-control study to evaluate the use of oral misoprostol in near term (> or =35 weeks) twin pregnancies in nulliparas. Eligible cases were given 100 mcg oral misoprostol, which was repeated after 6 h if labor did not start. Either a third dose or diluted oxytocin infusion were given in intractable cases. Diluted oxytocin infusion was used for augmentation. Controls were nulliparas delivered at > or =35 weeks by elective cesarean section. The two groups were comparable in most aspects, except for fetal malpresentation, which was the major reason for avoiding induction. Of the 69 patients in whom labor was induced, 53 (76.8%) had a vaginal birth, 3 (4.3%) had a combined twin delivery, and 13 (18.8%) had a cesarean during labor. The mean length of stay of the neonates was significantly shorter among study cases, without significant difference in the frequency of delayed discharges as an overall proxy for neonatal complications. Labor induction with oral misoprostol could be offered to patients in whom near term vaginal twin delivery is unequivocally permitted and wish to deliver by the vaginal route. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006 2006-01-01T00:00:00Z 2017-01-11T15:48:59Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/2615 |
url |
http://hdl.handle.net/10400.17/2615 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
J Perinat Med. 2006;34(2):111-4. 10.1515/JPM.2006.020 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
De Gruyter |
publisher.none.fl_str_mv |
De Gruyter |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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1777302270799511552 |