First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/2604 |
Resumo: | Anti-NMDA receptor encephalitis is an autoimmune disease that was identified in 2007, and manifests in a stepwise manner with psychiatric, neurological and autonomic symptoms. The disease is caused by autoantibodies against NMDA receptors. It can have a paraneoplastic origin, mainly secondary to ovarian teratomas, but it can also be unrelated to the tumor. This disease can affect both sexes and all ages. CASE PRESENTATION: Here, we present a case of a 15 year-old female adolescent with first-episode psychosis with anti-NMDA receptor encephalitis not related to tumor, which manifested with delusion, hallucinations, panic attacks, agitation, and neurological symptoms, and later with autonomic instability. She was treated with immunotherapy and psychiatric medication resulting in improvement of her main psychiatric and neurological symptoms. CONCLUSION: Our main objective in presenting this case is to alert clinicians to this challenging and recent disease that has a clinical presentation that might resemble a functional psychiatric condition and can be underdiagnosed in the context of child and adolescent psychiatry. |
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First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the LiteratureAnti-NMDA receptor encephalitisFirst-episode psychosisPsychosisAdolescentCase ReportHDE PEDOPAnti-NMDA receptor encephalitis is an autoimmune disease that was identified in 2007, and manifests in a stepwise manner with psychiatric, neurological and autonomic symptoms. The disease is caused by autoantibodies against NMDA receptors. It can have a paraneoplastic origin, mainly secondary to ovarian teratomas, but it can also be unrelated to the tumor. This disease can affect both sexes and all ages. CASE PRESENTATION: Here, we present a case of a 15 year-old female adolescent with first-episode psychosis with anti-NMDA receptor encephalitis not related to tumor, which manifested with delusion, hallucinations, panic attacks, agitation, and neurological symptoms, and later with autonomic instability. She was treated with immunotherapy and psychiatric medication resulting in improvement of her main psychiatric and neurological symptoms. CONCLUSION: Our main objective in presenting this case is to alert clinicians to this challenging and recent disease that has a clinical presentation that might resemble a functional psychiatric condition and can be underdiagnosed in the context of child and adolescent psychiatry.BioMed CentralRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEMoura, MSilva-Dos-Santos, AAfonso, JTalina, M2017-01-11T10:21:49Z2016-07-292016-07-29T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2604engBMC Res Notes. 2016 Jul 29;9:37410.1186/s13104-016-2180-6info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:38:38Zoai:repositorio.chlc.min-saude.pt:10400.17/2604Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:19:57.065085Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature |
title |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature |
spellingShingle |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature Moura, M Anti-NMDA receptor encephalitis First-episode psychosis Psychosis Adolescent Case Report HDE PEDOP |
title_short |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature |
title_full |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature |
title_fullStr |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature |
title_full_unstemmed |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature |
title_sort |
First-Episode Psychosis in a 15 Year-Old Female with Clinical Presentation of Anti-NMDA Receptor Encephalitis: A Case Report and Review of the Literature |
author |
Moura, M |
author_facet |
Moura, M Silva-Dos-Santos, A Afonso, J Talina, M |
author_role |
author |
author2 |
Silva-Dos-Santos, A Afonso, J Talina, M |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Moura, M Silva-Dos-Santos, A Afonso, J Talina, M |
dc.subject.por.fl_str_mv |
Anti-NMDA receptor encephalitis First-episode psychosis Psychosis Adolescent Case Report HDE PEDOP |
topic |
Anti-NMDA receptor encephalitis First-episode psychosis Psychosis Adolescent Case Report HDE PEDOP |
description |
Anti-NMDA receptor encephalitis is an autoimmune disease that was identified in 2007, and manifests in a stepwise manner with psychiatric, neurological and autonomic symptoms. The disease is caused by autoantibodies against NMDA receptors. It can have a paraneoplastic origin, mainly secondary to ovarian teratomas, but it can also be unrelated to the tumor. This disease can affect both sexes and all ages. CASE PRESENTATION: Here, we present a case of a 15 year-old female adolescent with first-episode psychosis with anti-NMDA receptor encephalitis not related to tumor, which manifested with delusion, hallucinations, panic attacks, agitation, and neurological symptoms, and later with autonomic instability. She was treated with immunotherapy and psychiatric medication resulting in improvement of her main psychiatric and neurological symptoms. CONCLUSION: Our main objective in presenting this case is to alert clinicians to this challenging and recent disease that has a clinical presentation that might resemble a functional psychiatric condition and can be underdiagnosed in the context of child and adolescent psychiatry. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-07-29 2016-07-29T00:00:00Z 2017-01-11T10:21:49Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/2604 |
url |
http://hdl.handle.net/10400.17/2604 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMC Res Notes. 2016 Jul 29;9:374 10.1186/s13104-016-2180-6 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central |
publisher.none.fl_str_mv |
BioMed Central |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131296150061056 |