Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/47008 |
Resumo: | In recent years, the combination of natural polymers with nanoparticles has permitted the development of sophisticated and efficient bioinspired constructs. In this regard, the incorporation of bioactive glass nanoparticles (BGNPs) confers a bioactive nature to these constructs, which can then induce the formation of a bone-like apatite layer upon immersion in a physiological environment. Moreover, the incorporation of bioactive glass nanoparticles has been found to be beneficial; the constructs proved to be biocompatible, promote cell adhesion and spreading, and regulate osteogenic commitment. This review provides a summary and discussion of the composition, design, and applications of bioinspired nanocomposite constructs based on BGNPs. Examples of nanocomposite systems will be highlighted with relevance to biomedical applications. It is expected that understanding the principles and the stateof-the-art of natural nanocomposites may lead to breakthroughs in many research areas, including tissue engineering and orthopaedic devices. The challenges regarding the future translation of these nanostructured composites into clinical use are also summarized. |
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Biomedical applications of natural-based polymers combined with bioactive glass nanoparticlesBioactive glass NanoparticlesNanocompositeNatural polymersScience & TechnologyIn recent years, the combination of natural polymers with nanoparticles has permitted the development of sophisticated and efficient bioinspired constructs. In this regard, the incorporation of bioactive glass nanoparticles (BGNPs) confers a bioactive nature to these constructs, which can then induce the formation of a bone-like apatite layer upon immersion in a physiological environment. Moreover, the incorporation of bioactive glass nanoparticles has been found to be beneficial; the constructs proved to be biocompatible, promote cell adhesion and spreading, and regulate osteogenic commitment. This review provides a summary and discussion of the composition, design, and applications of bioinspired nanocomposite constructs based on BGNPs. Examples of nanocomposite systems will be highlighted with relevance to biomedical applications. It is expected that understanding the principles and the stateof-the-art of natural nanocomposites may lead to breakthroughs in many research areas, including tissue engineering and orthopaedic devices. The challenges regarding the future translation of these nanostructured composites into clinical use are also summarized.A´lvaro J. Leite acknowledges the Portuguese Foundation for Science and Technology (FCT) for his doctoral grant (SFRH/BD/73174/2010).info:eu-repo/semantics/publishedVersionRoyal Society of ChemistryUniversidade do MinhoLeite, Álvaro J.Mano, J. F.2017-052017-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/47008engLeite A. J., Mano J. F. Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles, Journal Of Materials Chemistry B, Vol. 5, Issue 24, pp. 4555--4568, doi:10.1039/C7TB00404D, 20172050-750X2050-751810.1039/c7tb00404d32264298http://pubs.rsc.org/en/content/articlelanding/2017/tb/c7tb00404d#!divAbstractinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:59:54Zoai:repositorium.sdum.uminho.pt:1822/47008Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:49:43.475015Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles |
title |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles |
spellingShingle |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles Leite, Álvaro J. Bioactive glass Nanoparticles Nanocomposite Natural polymers Science & Technology |
title_short |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles |
title_full |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles |
title_fullStr |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles |
title_full_unstemmed |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles |
title_sort |
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles |
author |
Leite, Álvaro J. |
author_facet |
Leite, Álvaro J. Mano, J. F. |
author_role |
author |
author2 |
Mano, J. F. |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Leite, Álvaro J. Mano, J. F. |
dc.subject.por.fl_str_mv |
Bioactive glass Nanoparticles Nanocomposite Natural polymers Science & Technology |
topic |
Bioactive glass Nanoparticles Nanocomposite Natural polymers Science & Technology |
description |
In recent years, the combination of natural polymers with nanoparticles has permitted the development of sophisticated and efficient bioinspired constructs. In this regard, the incorporation of bioactive glass nanoparticles (BGNPs) confers a bioactive nature to these constructs, which can then induce the formation of a bone-like apatite layer upon immersion in a physiological environment. Moreover, the incorporation of bioactive glass nanoparticles has been found to be beneficial; the constructs proved to be biocompatible, promote cell adhesion and spreading, and regulate osteogenic commitment. This review provides a summary and discussion of the composition, design, and applications of bioinspired nanocomposite constructs based on BGNPs. Examples of nanocomposite systems will be highlighted with relevance to biomedical applications. It is expected that understanding the principles and the stateof-the-art of natural nanocomposites may lead to breakthroughs in many research areas, including tissue engineering and orthopaedic devices. The challenges regarding the future translation of these nanostructured composites into clinical use are also summarized. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-05 2017-05-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/47008 |
url |
http://hdl.handle.net/1822/47008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Leite A. J., Mano J. F. Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles, Journal Of Materials Chemistry B, Vol. 5, Issue 24, pp. 4555--4568, doi:10.1039/C7TB00404D, 2017 2050-750X 2050-7518 10.1039/c7tb00404d 32264298 http://pubs.rsc.org/en/content/articlelanding/2017/tb/c7tb00404d#!divAbstract |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Royal Society of Chemistry |
publisher.none.fl_str_mv |
Royal Society of Chemistry |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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