A rare cause of agranulocytosis

Detalhes bibliográficos
Autor(a) principal: Luís, Helena
Data de Publicação: 2021
Outros Autores: Barros, Carolina, Fernandes, Mauro, Granito, Sofia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/37858
Resumo: Clozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications. We present a case of a 42-year-old Caucasian woman with a 4-year history of persistent delusion disorder, who presented with fatigue and fever and was ultimately diagnosed with agranulocytosis due to clozapine. Clozapine-induced granulocytosis is an uncommon condition, but potentially fatal in consequences. Each patient with an episode of agranulocytosis should be assessed individually, with special attention to risk factors. Upon that, the decision about clozapine rechallenge or withdrawal should be made
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spelling A rare cause of agranulocytosisagranulocytosisClozapineRegião Autónoma da MadeiraClozapine - risk factorsPortugalMadeira IslandClozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications. We present a case of a 42-year-old Caucasian woman with a 4-year history of persistent delusion disorder, who presented with fatigue and fever and was ultimately diagnosed with agranulocytosis due to clozapine. Clozapine-induced granulocytosis is an uncommon condition, but potentially fatal in consequences. Each patient with an episode of agranulocytosis should be assessed individually, with special attention to risk factors. Upon that, the decision about clozapine rechallenge or withdrawal should be madeOAT-Open Acess TextRepositório ComumLuís, HelenaBarros, CarolinaFernandes, MauroGranito, Sofia2021-10-29T16:15:45Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/37858engClin Case Rep Rev, 2021 doi: 10.15761/CCRR.10005012059-039310.15761/CCRR.1000501info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T02:18:41Zoai:comum.rcaap.pt:10400.26/37858Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:34:35.906812Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A rare cause of agranulocytosis
title A rare cause of agranulocytosis
spellingShingle A rare cause of agranulocytosis
Luís, Helena
agranulocytosis
Clozapine
Região Autónoma da Madeira
Clozapine - risk factors
Portugal
Madeira Island
title_short A rare cause of agranulocytosis
title_full A rare cause of agranulocytosis
title_fullStr A rare cause of agranulocytosis
title_full_unstemmed A rare cause of agranulocytosis
title_sort A rare cause of agranulocytosis
author Luís, Helena
author_facet Luís, Helena
Barros, Carolina
Fernandes, Mauro
Granito, Sofia
author_role author
author2 Barros, Carolina
Fernandes, Mauro
Granito, Sofia
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Luís, Helena
Barros, Carolina
Fernandes, Mauro
Granito, Sofia
dc.subject.por.fl_str_mv agranulocytosis
Clozapine
Região Autónoma da Madeira
Clozapine - risk factors
Portugal
Madeira Island
topic agranulocytosis
Clozapine
Região Autónoma da Madeira
Clozapine - risk factors
Portugal
Madeira Island
description Clozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications. We present a case of a 42-year-old Caucasian woman with a 4-year history of persistent delusion disorder, who presented with fatigue and fever and was ultimately diagnosed with agranulocytosis due to clozapine. Clozapine-induced granulocytosis is an uncommon condition, but potentially fatal in consequences. Each patient with an episode of agranulocytosis should be assessed individually, with special attention to risk factors. Upon that, the decision about clozapine rechallenge or withdrawal should be made
publishDate 2021
dc.date.none.fl_str_mv 2021-10-29T16:15:45Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/37858
url http://hdl.handle.net/10400.26/37858
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clin Case Rep Rev, 2021 doi: 10.15761/CCRR.1000501
2059-0393
10.15761/CCRR.1000501
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv OAT-Open Acess Text
publisher.none.fl_str_mv OAT-Open Acess Text
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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