Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature

Detalhes bibliográficos
Autor(a) principal: Carvalho Mendes, António
Data de Publicação: 2023
Outros Autores: Ponte, Alcina, Pereira, Amália, Gonçalves, Morna
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/1925
Resumo: A clinicai case-report of eosinophilic gastroenteritis, in a 36-year-old man, admitted for a 2º episode of incomplete abdominal obstruction in 2 years, is presented. As well as the clinicai picture of epigastric burning, cramping abdominal pain and vomiting the patient had an eosinophilic ascitis and eosinophilia was present on the full blood count. There was no history of allergy. Endoscopic and Japaroscopic biopsies revealed intense eosinophilic infiltration involving both serosa] and muscular layers and a mild eosinophilic in.iltration of the intestinal mucosa. There was no evidence of intestinal parasitosis. A short course of oral steroids was started and there was an impressive improvement of symptoms and resolution of ascites within a week. This case shows (1) a rare disease, (2) a non-surgical cause of acute abdominal pain of obscure origin, (3) the chronicity and relapsing character of the disease, and (4) the efficacy of short course steroids. We review the literature focusing on new aspects of eosinophil pathogenesis and the interface with idiopathic hypereosinophilic syndrome.
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spelling Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literatureAbdómen agudo com ascite, como apresentação de gastroenterite eosinofílica - Caso clínico e revisão da litera­turagastroenterite eosinofilicaascite eosinofilicaeosinofiliaabdómen agudoeosinophilic gastroenteritiseosinophilic asciteseosinophiliaacute abdomenA clinicai case-report of eosinophilic gastroenteritis, in a 36-year-old man, admitted for a 2º episode of incomplete abdominal obstruction in 2 years, is presented. As well as the clinicai picture of epigastric burning, cramping abdominal pain and vomiting the patient had an eosinophilic ascitis and eosinophilia was present on the full blood count. There was no history of allergy. Endoscopic and Japaroscopic biopsies revealed intense eosinophilic infiltration involving both serosa] and muscular layers and a mild eosinophilic in.iltration of the intestinal mucosa. There was no evidence of intestinal parasitosis. A short course of oral steroids was started and there was an impressive improvement of symptoms and resolution of ascites within a week. This case shows (1) a rare disease, (2) a non-surgical cause of acute abdominal pain of obscure origin, (3) the chronicity and relapsing character of the disease, and (4) the efficacy of short course steroids. We review the literature focusing on new aspects of eosinophil pathogenesis and the interface with idiopathic hypereosinophilic syndrome.Apresentamos um caso de gastroenterite eosinofilica num homem de 36 anos admitido no nosso hospital por 2º episódio de quadro obstrutivo intestinal incompleto nos últimos 2 anos. Além de ardor epigástrico, vómitos, dor e distensão timpânica abdominal apresentava ainda ascite eosinofilica e eosinofilia periférica. As biopsias do tubo digestivo por via endoscópíca e laparoscópica demonstraram intensa infiltração eosinofilica do peritoneu e do estômago, envolvendo as túnicas serosa e muscular e, em menor grau, da mucosa cólica. Descartadas outras causas de eosinofilia periférica, nomeadamente infecção parasitária, iniciou corticoterapia com melhoria dramática dos sintomas e resolução da ascite e da eosinofilia, o que permitiu o seu desmame progressivo, encontrando-se até à data assintomático e livre de recidiva. Este caso ilustra: (1) um diagnóstico raro; (2) uma causa não cirúrgica adicional a considerar no diagnóstico diferencial de abdómen agudo; (3) o carácter crónico e recidivante da doença; e (4) o sucesso clínico da corticoterapia em regime curto. Procede-se a uma revisão da literatura, focando aspectos inovadores da patogénese e o controverso diagnóstico diferencial com a síndroma hipereosinofílica idiopática.Sociedade Portuguesa de Medicina Interna2023-06-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spmi.pt/index.php/rpmi/article/view/1925Internal Medicine; Vol. 8 No. 4 (2001): Outubro/ Dezembro; 196-204Medicina Interna; Vol. 8 N.º 4 (2001): Outubro/ Dezembro; 196-2042183-99800872-671Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spmi.pt/index.php/rpmi/article/view/1925https://revista.spmi.pt/index.php/rpmi/article/view/1925/1351Carvalho Mendes, AntónioPonte, AlcinaPereira, AmáliaGonçalves, Mornainfo:eu-repo/semantics/openAccess2023-06-10T06:10:58Zoai:oai.revista.spmi.pt:article/1925Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:00:05.037725Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
Abdómen agudo com ascite, como apresentação de gastroenterite eosinofílica - Caso clínico e revisão da litera­tura
title Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
spellingShingle Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
Carvalho Mendes, António
gastroenterite eosinofilica
ascite eosinofilica
eosinofilia
abdómen agudo
eosinophilic gastroenteritis
eosinophilic ascites
eosinophilia
acute abdomen
title_short Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
title_full Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
title_fullStr Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
title_full_unstemmed Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
title_sort Eosinophilic gastroenteritis presenting as an acute abdomen with ascites - A case report and review of the literature
author Carvalho Mendes, António
author_facet Carvalho Mendes, António
Ponte, Alcina
Pereira, Amália
Gonçalves, Morna
author_role author
author2 Ponte, Alcina
Pereira, Amália
Gonçalves, Morna
author2_role author
author
author
dc.contributor.author.fl_str_mv Carvalho Mendes, António
Ponte, Alcina
Pereira, Amália
Gonçalves, Morna
dc.subject.por.fl_str_mv gastroenterite eosinofilica
ascite eosinofilica
eosinofilia
abdómen agudo
eosinophilic gastroenteritis
eosinophilic ascites
eosinophilia
acute abdomen
topic gastroenterite eosinofilica
ascite eosinofilica
eosinofilia
abdómen agudo
eosinophilic gastroenteritis
eosinophilic ascites
eosinophilia
acute abdomen
description A clinicai case-report of eosinophilic gastroenteritis, in a 36-year-old man, admitted for a 2º episode of incomplete abdominal obstruction in 2 years, is presented. As well as the clinicai picture of epigastric burning, cramping abdominal pain and vomiting the patient had an eosinophilic ascitis and eosinophilia was present on the full blood count. There was no history of allergy. Endoscopic and Japaroscopic biopsies revealed intense eosinophilic infiltration involving both serosa] and muscular layers and a mild eosinophilic in.iltration of the intestinal mucosa. There was no evidence of intestinal parasitosis. A short course of oral steroids was started and there was an impressive improvement of symptoms and resolution of ascites within a week. This case shows (1) a rare disease, (2) a non-surgical cause of acute abdominal pain of obscure origin, (3) the chronicity and relapsing character of the disease, and (4) the efficacy of short course steroids. We review the literature focusing on new aspects of eosinophil pathogenesis and the interface with idiopathic hypereosinophilic syndrome.
publishDate 2023
dc.date.none.fl_str_mv 2023-06-06
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url https://revista.spmi.pt/index.php/rpmi/article/view/1925
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/1925
https://revista.spmi.pt/index.php/rpmi/article/view/1925/1351
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
dc.source.none.fl_str_mv Internal Medicine; Vol. 8 No. 4 (2001): Outubro/ Dezembro; 196-204
Medicina Interna; Vol. 8 N.º 4 (2001): Outubro/ Dezembro; 196-204
2183-9980
0872-671X
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