Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films

Detalhes bibliográficos
Autor(a) principal: Albuquerque, Priscilla B. S.
Data de Publicação: 2023
Outros Autores: de Souza, M. P., Bourbon, Ana I., Cerqueira, Miguel A., Pastrana, L., Jauregi, P., Teixeira, J. A., Carneiro-da-Cunha, M. das Graças
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/85566
Resumo: Data Availability Statement: Data supporting reported results of this work are contained within the article. The data presented in this study are available in the following articles: “Cross-linked chi- tosan/liposome hybrid system for the intestinal delivery of quercetin”, “Immobilization of bioactive compounds in Cassia grandis galactomannan-based films: Influence on physicochemical properties”, “Delonix regia galactomannan-based edible films: Effect of molecular weight and k-carrageenan on physicochemical properties”, “Development of edible films prepared by soy protein and the galactomannan fraction extracted from Gleditsia triacanthos (Fabaceae) seed”, and “Preparation and characterization of konjac glucomannan-based bionanocomposite film for active food packaging”.
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spelling Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based filmsbioactive compoundsbiopolymersheath applicationsencapsulationpolysaccharidesData Availability Statement: Data supporting reported results of this work are contained within the article. The data presented in this study are available in the following articles: “Cross-linked chi- tosan/liposome hybrid system for the intestinal delivery of quercetin”, “Immobilization of bioactive compounds in Cassia grandis galactomannan-based films: Influence on physicochemical properties”, “Delonix regia galactomannan-based edible films: Effect of molecular weight and k-carrageenan on physicochemical properties”, “Development of edible films prepared by soy protein and the galactomannan fraction extracted from Gleditsia triacanthos (Fabaceae) seed”, and “Preparation and characterization of konjac glucomannan-based bionanocomposite film for active food packaging”.The objective of this work was to prepare different concentrations of liposomes based on lecithin containing quercetin, and evaluate their effect on the properties of galactomannan films obtained from Cassia grandis seeds. Quercetin-loaded lecithin liposomes (QT-LL) were obtained by the ethanol injection method by incorporating quercetin in different concentrations in a previously prepared suspension of lecithin liposomes in water. Following characterization of QT-LLs by zeta potential and dynamic light scattering, QT-LL with 75 µg quercetin/mL suspension was incorporated at different concentrations in galactomannan films. The films obtained were characterized for color, solubility, moisture content (MC), water vapor permeability (WVP), scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier-transform infrared (FTIR) spectroscopy. The size of lecithin liposomes with no quercetin was statistically than those containing quercetin above 50 µg/mL. All the QT-LLs presented a low polydispersity index, even considering their significant differences and similar values for zeta potential. The films displayed a rough surface and the galactomannan structure was confirmed by FTIR. Additionally, the amorphous nature of the polysaccharide was observed by XRD. The films were luminous, with a predominant yellow tendency and low opacity. The incorporation of QT-LL in galactomannan films did not lead to statistical differences for solubility and MC, while significant differences were observed for WVP. Galactomannan films were shown to be a promising structure for the incorporation of lecithin liposomes loaded with quercetin, pointing at promising applications for different applications.This study was supported by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) and under the scope of the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462). P.A. receipted a scholarship from CAPES. M.d.G.C.-d.-C. express her gratitude to the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) for research grants and fellowship. The authors acknowledge CNPq and CAPES for financial support.info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoAlbuquerque, Priscilla B. S.de Souza, M. P.Bourbon, Ana I.Cerqueira, Miguel A.Pastrana, L.Jauregi, P.Teixeira, J. A.Carneiro-da-Cunha, M. das Graças2023-05-312023-05-31T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/85566engAlbuquerque, Priscilla B. S.; de Souza, M. P.; Bourbon, Ana I.; Cerqueira, Miguel A.; Pastrana, L.; Jauregi, P.; Teixeira, José A.; Carneiro-da-Cunha, M. das Graças, Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films. Applied Nano, 4(2), 159-177, 20232673-350110.3390/applnano4020009https://www.mdpi.com/2673-3501/4/2/9info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:56:13ZPortal AgregadorONG
dc.title.none.fl_str_mv Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
title Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
spellingShingle Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
Albuquerque, Priscilla B. S.
bioactive compounds
biopolymers
heath applications
encapsulation
polysaccharides
title_short Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
title_full Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
title_fullStr Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
title_full_unstemmed Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
title_sort Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films
author Albuquerque, Priscilla B. S.
author_facet Albuquerque, Priscilla B. S.
de Souza, M. P.
Bourbon, Ana I.
Cerqueira, Miguel A.
Pastrana, L.
Jauregi, P.
Teixeira, J. A.
Carneiro-da-Cunha, M. das Graças
author_role author
author2 de Souza, M. P.
Bourbon, Ana I.
Cerqueira, Miguel A.
Pastrana, L.
Jauregi, P.
Teixeira, J. A.
Carneiro-da-Cunha, M. das Graças
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Albuquerque, Priscilla B. S.
de Souza, M. P.
Bourbon, Ana I.
Cerqueira, Miguel A.
Pastrana, L.
Jauregi, P.
Teixeira, J. A.
Carneiro-da-Cunha, M. das Graças
dc.subject.por.fl_str_mv bioactive compounds
biopolymers
heath applications
encapsulation
polysaccharides
topic bioactive compounds
biopolymers
heath applications
encapsulation
polysaccharides
description Data Availability Statement: Data supporting reported results of this work are contained within the article. The data presented in this study are available in the following articles: “Cross-linked chi- tosan/liposome hybrid system for the intestinal delivery of quercetin”, “Immobilization of bioactive compounds in Cassia grandis galactomannan-based films: Influence on physicochemical properties”, “Delonix regia galactomannan-based edible films: Effect of molecular weight and k-carrageenan on physicochemical properties”, “Development of edible films prepared by soy protein and the galactomannan fraction extracted from Gleditsia triacanthos (Fabaceae) seed”, and “Preparation and characterization of konjac glucomannan-based bionanocomposite film for active food packaging”.
publishDate 2023
dc.date.none.fl_str_mv 2023-05-31
2023-05-31T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/85566
url https://hdl.handle.net/1822/85566
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Albuquerque, Priscilla B. S.; de Souza, M. P.; Bourbon, Ana I.; Cerqueira, Miguel A.; Pastrana, L.; Jauregi, P.; Teixeira, José A.; Carneiro-da-Cunha, M. das Graças, Production and properties of quercetin-loaded liposomes and their influence on the properties of galactomannan-based films. Applied Nano, 4(2), 159-177, 2023
2673-3501
10.3390/applnano4020009
https://www.mdpi.com/2673-3501/4/2/9
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
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