Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome.
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735 |
Resumo: | Cerebral venous thrombosis is a rare but potentially severe condition in children. We present the case of a teenager with corticodependent nephrotic syndrome diagnosed at five months of age and treated with cyclosporine A. In the context of recurrence of nephrotic syndrome he presented with headache, vomiting and severe intracranial hypertension. While the raised intracranial pressure and the status epilepticus were controlled, the brain imaging revealed venous thrombosis of all venous sinus, with absence of venous drainage. He was submitted to local thrombolysis with recombinant tissue plasminogen activator, with recanalization of the venous sinuses. The outcome was favourable, without neurological deficits. In this case, the early radiologic intervention was crucial, enabling a full neurological recovery, in a teenager whose initial prognosis was very poor. |
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Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome.Trombose venosa cerebral maciça submetida a trombólise endovascular num adolescente com síndrome nefrótica.Cerebral venous thrombosis is a rare but potentially severe condition in children. We present the case of a teenager with corticodependent nephrotic syndrome diagnosed at five months of age and treated with cyclosporine A. In the context of recurrence of nephrotic syndrome he presented with headache, vomiting and severe intracranial hypertension. While the raised intracranial pressure and the status epilepticus were controlled, the brain imaging revealed venous thrombosis of all venous sinus, with absence of venous drainage. He was submitted to local thrombolysis with recombinant tissue plasminogen activator, with recanalization of the venous sinuses. The outcome was favourable, without neurological deficits. In this case, the early radiologic intervention was crucial, enabling a full neurological recovery, in a teenager whose initial prognosis was very poor.Cerebral venous thrombosis is a rare but potentially severe condition in children. We present the case of a teenager with corticodependent nephrotic syndrome diagnosed at five months of age and treated with cyclosporine A. In the context of recurrence of nephrotic syndrome he presented with headache, vomiting and severe intracranial hypertension. While the raised intracranial pressure and the status epilepticus were controlled, the brain imaging revealed venous thrombosis of all venous sinus, with absence of venous drainage. He was submitted to local thrombolysis with recombinant tissue plasminogen activator, with recanalization of the venous sinuses. The outcome was favourable, without neurological deficits. In this case, the early radiologic intervention was crucial, enabling a full neurological recovery, in a teenager whose initial prognosis was very poor.Ordem dos Médicos2010-12-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735oai:ojs.www.actamedicaportuguesa.com:article/735Acta Médica Portuguesa; Vol. 23 No. 6 (2010): November-December; 1141-6Acta Médica Portuguesa; Vol. 23 N.º 6 (2010): Novembro-Dezembro; 1141-61646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735/412Costa, PaulaBiscoito, LuísaVieira, MarisaMarçal, MónicaCamilo, CristinaNeto, LiaAbecasis, FranciscoAlmeida, MargaridaCorreia, Manuelainfo:eu-repo/semantics/openAccess2022-12-20T10:56:50Zoai:ojs.www.actamedicaportuguesa.com:article/735Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:43.426980Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. Trombose venosa cerebral maciça submetida a trombólise endovascular num adolescente com síndrome nefrótica. |
title |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. |
spellingShingle |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. Costa, Paula |
title_short |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. |
title_full |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. |
title_fullStr |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. |
title_full_unstemmed |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. |
title_sort |
Endovascular thrombolysis for massive cerebral venous thrombosis in a teenager with nephrotic syndrome. |
author |
Costa, Paula |
author_facet |
Costa, Paula Biscoito, Luísa Vieira, Marisa Marçal, Mónica Camilo, Cristina Neto, Lia Abecasis, Francisco Almeida, Margarida Correia, Manuela |
author_role |
author |
author2 |
Biscoito, Luísa Vieira, Marisa Marçal, Mónica Camilo, Cristina Neto, Lia Abecasis, Francisco Almeida, Margarida Correia, Manuela |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Costa, Paula Biscoito, Luísa Vieira, Marisa Marçal, Mónica Camilo, Cristina Neto, Lia Abecasis, Francisco Almeida, Margarida Correia, Manuela |
description |
Cerebral venous thrombosis is a rare but potentially severe condition in children. We present the case of a teenager with corticodependent nephrotic syndrome diagnosed at five months of age and treated with cyclosporine A. In the context of recurrence of nephrotic syndrome he presented with headache, vomiting and severe intracranial hypertension. While the raised intracranial pressure and the status epilepticus were controlled, the brain imaging revealed venous thrombosis of all venous sinus, with absence of venous drainage. He was submitted to local thrombolysis with recombinant tissue plasminogen activator, with recanalization of the venous sinuses. The outcome was favourable, without neurological deficits. In this case, the early radiologic intervention was crucial, enabling a full neurological recovery, in a teenager whose initial prognosis was very poor. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12-28 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735 oai:ojs.www.actamedicaportuguesa.com:article/735 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/735 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/735/412 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 23 No. 6 (2010): November-December; 1141-6 Acta Médica Portuguesa; Vol. 23 N.º 6 (2010): Novembro-Dezembro; 1141-6 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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