Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/23230 |
Resumo: | In Europe alone, over 70 million people experience tinnitus; for seven million people, it creates a debilitating condition. Despite its enormous socioeconomic relevance, progress in successfully treating the condition is somewhat limited. The European Union has approved funding to create a pan-European tinnitus research collaboration network (2014-2018). The goal of one working group is to establish an international standard for outcome measurements in clinical trials of tinnitus. Importantly, this would enhance tinnitus research by informing sample-size calculations, enabling meta-analyses, and facilitating the identification of tinnitus subtypes, ultimately leading to improved treatments. The first meeting followed a workshop on ``Agreed Standards for Measurement: An International Perspective{''} with invited talks on clinimetrics and existing international initiatives to define core sets for outcome measurements in hearing loss (International classification of functioning, disability, and health core sets for hearing loss) and eczema (Harmonizing outcome measures for eczema). Both initiatives have taken an approach that clearly distinguishes the specification of what to measure from that of how to measure it. Meeting delegates agreed on taking a step-wise roadmap for which the first output would be a consensus on what outcome domains are essential for all trials. The working group seeks to embrace inclusivity and brings together clinicians, tinnitus researchers, experts on clinical research methodology, statisticians, and representatives of the health industry. People who experience tinnitus are another important participant group. This meeting report is a call to those stakeholders across the globe to actively participate in the initiative.} |
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Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The NetherlandstinnitusMANAGEMENToutcome assessmentpopulation characteristicsmeasurementstandardizationclinical trialtinnitusoutcome assessmentstandardizationmeasurementclinical trialpopulation characteristicsIn Europe alone, over 70 million people experience tinnitus; for seven million people, it creates a debilitating condition. Despite its enormous socioeconomic relevance, progress in successfully treating the condition is somewhat limited. The European Union has approved funding to create a pan-European tinnitus research collaboration network (2014-2018). The goal of one working group is to establish an international standard for outcome measurements in clinical trials of tinnitus. Importantly, this would enhance tinnitus research by informing sample-size calculations, enabling meta-analyses, and facilitating the identification of tinnitus subtypes, ultimately leading to improved treatments. The first meeting followed a workshop on ``Agreed Standards for Measurement: An International Perspective{''} with invited talks on clinimetrics and existing international initiatives to define core sets for outcome measurements in hearing loss (International classification of functioning, disability, and health core sets for hearing loss) and eczema (Harmonizing outcome measures for eczema). Both initiatives have taken an approach that clearly distinguishes the specification of what to measure from that of how to measure it. Meeting delegates agreed on taking a step-wise roadmap for which the first output would be a consensus on what outcome domains are essential for all trials. The working group seeks to embrace inclusivity and brings together clinicians, tinnitus researchers, experts on clinical research methodology, statisticians, and representatives of the health industry. People who experience tinnitus are another important participant group. This meeting report is a call to those stakeholders across the globe to actively participate in the initiative.}NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNHall, Deborah AHaider, HaúlaKikidis, DimitrisMielczarek, MarzenaMazurek, BirgitSzczepek, Agnieszka JCederroth, Christopher R2017-09-13T22:01:39Z2015-012015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://hdl.handle.net/10362/23230eng2331-2165PURE: 486389https://doi.org/10.1177/2331216515580272info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:11:28Zoai:run.unl.pt:10362/23230Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:27:43.034025Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands |
title |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands |
spellingShingle |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands Hall, Deborah A tinnitus MANAGEMENT outcome assessment population characteristics measurement standardization clinical trial tinnitus outcome assessment standardization measurement clinical trial population characteristics |
title_short |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands |
title_full |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands |
title_fullStr |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands |
title_full_unstemmed |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands |
title_sort |
Toward a global consensus on outcome measures for clinical trials in Tinnitus: report from the First International Meeting of the COMiT Initiative, November 14, 2014, Amsterdam, The Netherlands |
author |
Hall, Deborah A |
author_facet |
Hall, Deborah A Haider, Haúla Kikidis, Dimitris Mielczarek, Marzena Mazurek, Birgit Szczepek, Agnieszka J Cederroth, Christopher R |
author_role |
author |
author2 |
Haider, Haúla Kikidis, Dimitris Mielczarek, Marzena Mazurek, Birgit Szczepek, Agnieszka J Cederroth, Christopher R |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Hall, Deborah A Haider, Haúla Kikidis, Dimitris Mielczarek, Marzena Mazurek, Birgit Szczepek, Agnieszka J Cederroth, Christopher R |
dc.subject.por.fl_str_mv |
tinnitus MANAGEMENT outcome assessment population characteristics measurement standardization clinical trial tinnitus outcome assessment standardization measurement clinical trial population characteristics |
topic |
tinnitus MANAGEMENT outcome assessment population characteristics measurement standardization clinical trial tinnitus outcome assessment standardization measurement clinical trial population characteristics |
description |
In Europe alone, over 70 million people experience tinnitus; for seven million people, it creates a debilitating condition. Despite its enormous socioeconomic relevance, progress in successfully treating the condition is somewhat limited. The European Union has approved funding to create a pan-European tinnitus research collaboration network (2014-2018). The goal of one working group is to establish an international standard for outcome measurements in clinical trials of tinnitus. Importantly, this would enhance tinnitus research by informing sample-size calculations, enabling meta-analyses, and facilitating the identification of tinnitus subtypes, ultimately leading to improved treatments. The first meeting followed a workshop on ``Agreed Standards for Measurement: An International Perspective{''} with invited talks on clinimetrics and existing international initiatives to define core sets for outcome measurements in hearing loss (International classification of functioning, disability, and health core sets for hearing loss) and eczema (Harmonizing outcome measures for eczema). Both initiatives have taken an approach that clearly distinguishes the specification of what to measure from that of how to measure it. Meeting delegates agreed on taking a step-wise roadmap for which the first output would be a consensus on what outcome domains are essential for all trials. The working group seeks to embrace inclusivity and brings together clinicians, tinnitus researchers, experts on clinical research methodology, statisticians, and representatives of the health industry. People who experience tinnitus are another important participant group. This meeting report is a call to those stakeholders across the globe to actively participate in the initiative.} |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-01 2015-01-01T00:00:00Z 2017-09-13T22:01:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/23230 |
url |
http://hdl.handle.net/10362/23230 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2331-2165 PURE: 486389 https://doi.org/10.1177/2331216515580272 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
7 application/pdf |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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