CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM

Detalhes bibliográficos
Autor(a) principal: Francisco, Telma
Data de Publicação: 2013
Outros Autores: Cunha, Daniela, Vieira, Raquel, Afonso, Ana, Brito, Maria João
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.71.1.138
Resumo: Cutaneous tuberculosis is an uncommon disease, accounting for 1.5% of all types of tuberculosis. In pulmonary and cutaneous disease, infections caused by Mycobacterium africanum and Mycobacterium tuberculosis can be clinically indistinguishable. A six-year-old boy from Guinea-Bissau was hospitalized due to a right pre-auricular ulcer with two-year evolution and regional lymphadenopathy. Tuberculinic test was positive and the thoracic radiography showed a hypotransparent node on the right lower pulmonary lobe, with solid characteristics in CT scan. Skin ulcer and lymphadenopathy biopsies revealed lymphocytic infiltrate with a granulomatous reaction; the culture and PCR confirmed Mycobacterium africanum infection. Antibacillary treatment was supplied for six months, leading to significant reduction of the lesion. In developed countries it’s important to remind the several forms of cutaneous tuberculosis, which can present solely or in association with other forms of infection. In patients from endemic areas, a positive tuberculinic test should rise the suspicion of this entity. KEY-WORDS – Tuberculosis, cutaneous; Tuberculosis, pulmonary; Mycobacterium infections; Child. 
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spelling CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUMINFEÇÃO CUTÂNEA E PULMONAR POR MYCOBACTERIUM AFRICANUMCutaneous tuberculosis is an uncommon disease, accounting for 1.5% of all types of tuberculosis. In pulmonary and cutaneous disease, infections caused by Mycobacterium africanum and Mycobacterium tuberculosis can be clinically indistinguishable. A six-year-old boy from Guinea-Bissau was hospitalized due to a right pre-auricular ulcer with two-year evolution and regional lymphadenopathy. Tuberculinic test was positive and the thoracic radiography showed a hypotransparent node on the right lower pulmonary lobe, with solid characteristics in CT scan. Skin ulcer and lymphadenopathy biopsies revealed lymphocytic infiltrate with a granulomatous reaction; the culture and PCR confirmed Mycobacterium africanum infection. Antibacillary treatment was supplied for six months, leading to significant reduction of the lesion. In developed countries it’s important to remind the several forms of cutaneous tuberculosis, which can present solely or in association with other forms of infection. In patients from endemic areas, a positive tuberculinic test should rise the suspicion of this entity. KEY-WORDS – Tuberculosis, cutaneous; Tuberculosis, pulmonary; Mycobacterium infections; Child. A tuberculose cutânea é uma doença incomum, constituindo 1,5% de todas as formas de tuberculose. Na doença pulmonar e cutânea, as infeções causadas por Mycobacterium africanum e Mycobacterium tuberculosis podem ser clinicamente indistinguíveis. Um rapaz de 6 anos da Guiné-Bissau foi hospitalizado devido a uma úlcera pré-auricular direita com evolução de dois anos e linfadenopatia regional. O teste tuberculínico foi positivo e a radiografia de tórax revelou um nódulo hipotransparente no lobo pulmonar direito, com características sólidas na TAC. As biópsias da úlcera e da linfadenopatia revelaram infiltrado linfocítico com reação granulomatosa; o exame cultural e a PCR confirmaram infeção por Mycobacterium africanum. Foi realizado tratamento antibacilar durante 6 meses, com redução significativa da lesão. Nos países desenvolvidos é importante relembrar as várias formas de tuberculose cutânea, que se pode apresentar isoladamente ou em associação com outras formas de infeção. Nos doentes provenientes de áreas endémicas, um teste tuberculínico positivo deve levantar a suspeita desta entidade. PALAVRAS-CHAVE – Tuberculose cutânea; Tuberculose pulmonar; Mycobacterium africanum; Criança. Sociedade Portuguesa de Dermatologia e Venereologia2013-06-23T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.71.1.138oai:ojs.revista.spdv.com.pt:article/138Journal of the Portuguese Society of Dermatology and Venereology; Vol 71 No 1 (2013): Janeiro - Março; 131-135Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 71 n. 1 (2013): Janeiro - Março; 131-1352182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spdv.com.pt/index.php/spdv/article/view/138https://doi.org/10.29021/spdv.71.1.138https://revista.spdv.com.pt/index.php/spdv/article/view/138/127Francisco, TelmaCunha, DanielaVieira, RaquelAfonso, AnaBrito, Maria Joãoinfo:eu-repo/semantics/openAccess2022-10-06T12:34:42Zoai:ojs.revista.spdv.com.pt:article/138Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:42.781307Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
INFEÇÃO CUTÂNEA E PULMONAR POR MYCOBACTERIUM AFRICANUM
title CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
spellingShingle CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
Francisco, Telma
title_short CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
title_full CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
title_fullStr CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
title_full_unstemmed CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
title_sort CUTANEOUS AND PULMONARY INFECTION BY MYCOBACTERIUM AFRICANUM
author Francisco, Telma
author_facet Francisco, Telma
Cunha, Daniela
Vieira, Raquel
Afonso, Ana
Brito, Maria João
author_role author
author2 Cunha, Daniela
Vieira, Raquel
Afonso, Ana
Brito, Maria João
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Francisco, Telma
Cunha, Daniela
Vieira, Raquel
Afonso, Ana
Brito, Maria João
description Cutaneous tuberculosis is an uncommon disease, accounting for 1.5% of all types of tuberculosis. In pulmonary and cutaneous disease, infections caused by Mycobacterium africanum and Mycobacterium tuberculosis can be clinically indistinguishable. A six-year-old boy from Guinea-Bissau was hospitalized due to a right pre-auricular ulcer with two-year evolution and regional lymphadenopathy. Tuberculinic test was positive and the thoracic radiography showed a hypotransparent node on the right lower pulmonary lobe, with solid characteristics in CT scan. Skin ulcer and lymphadenopathy biopsies revealed lymphocytic infiltrate with a granulomatous reaction; the culture and PCR confirmed Mycobacterium africanum infection. Antibacillary treatment was supplied for six months, leading to significant reduction of the lesion. In developed countries it’s important to remind the several forms of cutaneous tuberculosis, which can present solely or in association with other forms of infection. In patients from endemic areas, a positive tuberculinic test should rise the suspicion of this entity. KEY-WORDS – Tuberculosis, cutaneous; Tuberculosis, pulmonary; Mycobacterium infections; Child. 
publishDate 2013
dc.date.none.fl_str_mv 2013-06-23T00:00:00Z
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https://doi.org/10.29021/spdv.71.1.138
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publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 71 No 1 (2013): Janeiro - Março; 131-135
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 71 n. 1 (2013): Janeiro - Março; 131-135
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