Pancreatic Panniculitis – case report

Detalhes bibliográficos
Autor(a) principal: Tavares, Ermelindo Silva
Data de Publicação: 2010
Outros Autores: Parente, Joana Alexandra Devesa, Vera-Cruz, Frederico Pinto, Lima, José Nunes, Aranha, João Manuel Pires, Estrela, António Pedro Fernandes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://revista.spcir.com/index.php/spcir/article/view/118
Resumo: A 65-years-old female admitted on general surgery with acute pancreatitis, complicated with painful, erythematous and subcutaneous nodules, located on the legs, followed by poliarthritis. The combination of clinical and laboratory data as well as the results of skin biopsy confirmed the diagnosis of pancreatic panniculitis. The patient was treated with conservative therapy only led to her underlying pathology. A successful outcome and disappearance of the lesions were registered. Pancreatic panniculitis is a rare disorder that affects a small number of patients with pancreatic disorders, particularly pancreatitis (acute and chronic) and carcinoma of the pancreas. The disease is characterized by necrosis of subcutaneous adipose tissue and manifests itself usually by subcutaneous, erythematous and painful nodules, located preferentially on the lower limbs, and in more than half of the cases, there is inflammation of the periarticular fat. In the most cases, histopathology reveals lobular panniculitis and fat cells without nuclei (ghost cells). Treatment is conservative, aimed at the underlying pathology. Keywords: acute pancreatitis, pancreatic carcinoma, panniculitis, ghost cells. 
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spelling Pancreatic Panniculitis – case reportPaniculite Pancreática – caso clínicoA 65-years-old female admitted on general surgery with acute pancreatitis, complicated with painful, erythematous and subcutaneous nodules, located on the legs, followed by poliarthritis. The combination of clinical and laboratory data as well as the results of skin biopsy confirmed the diagnosis of pancreatic panniculitis. The patient was treated with conservative therapy only led to her underlying pathology. A successful outcome and disappearance of the lesions were registered. Pancreatic panniculitis is a rare disorder that affects a small number of patients with pancreatic disorders, particularly pancreatitis (acute and chronic) and carcinoma of the pancreas. The disease is characterized by necrosis of subcutaneous adipose tissue and manifests itself usually by subcutaneous, erythematous and painful nodules, located preferentially on the lower limbs, and in more than half of the cases, there is inflammation of the periarticular fat. In the most cases, histopathology reveals lobular panniculitis and fat cells without nuclei (ghost cells). Treatment is conservative, aimed at the underlying pathology. Keywords: acute pancreatitis, pancreatic carcinoma, panniculitis, ghost cells. Doente do sexo feminino, de 65 anos, internada no serviço de Cirurgia Geral por quadro de pancreatite aguda, complicado de nódulos subcutâneos, eritematosos, dolorosos, localizados nas pernas, acompanhados de poliartralgias. A conjugação dos dados clínicos e analíticos com o resultado da biópsia cutânea permitiu estabelecer o diagnóstico definitivo de paniculite pancreática. A paciente beneficiou apenas de terapêutica conservadora dirigida à patologia de base. Registou-se evolução clínica favorável com desaparecimento total das lesões. A paniculite pancreática é uma entidade clínica rara que afecta um número reduzido de doentes com distúrbio pancreático, particularmente pancreatite (aguda e crónica) e carcinoma do pâncreas. A doença caracteriza-se por necrose do tecido adiposo subcutâneo e manifesta-se, geralmente, por nódulos subcutâneos, eritematosos, dolorosos, localizados preferencialmente aos membros inferiores e, em mais de metade dos casos, verifica-se inflamação da gordura periarticular. O exame histopatológico, na maioria das vezes, revela paniculite lobular e adipócitos anucleados (“ghost cells”). O tratamento é conservador e direccionado à patologia de base. Palavras-chave: pancreatite aguda; carcinoma pancreático; paniculite; “ghost cells”. Sociedade Portuguesa de Cirurgia2010-12-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spcir.com/index.php/spcir/article/view/118Revista Portuguesa de Cirurgia; No 15 (2010): Dezembro 2010 - II Série; 31-34Revista Portuguesa de Cirurgia; No 15 (2010): Dezembro 2010 - II Série; 31-342183-11651646-6918reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spcir.com/index.php/spcir/article/view/118https://revista.spcir.com/index.php/spcir/article/view/118/116Copyright (c) 2016 Revista Portuguesa de Cirurgiainfo:eu-repo/semantics/openAccessTavares, Ermelindo SilvaParente, Joana Alexandra DevesaVera-Cruz, Frederico PintoLima, José NunesAranha, João Manuel PiresEstrela, António Pedro Fernandes2024-03-14T22:05:42Zoai:revista.spcir.com:article/118Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T04:00:57.590128Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Pancreatic Panniculitis – case report
Paniculite Pancreática – caso clínico
title Pancreatic Panniculitis – case report
spellingShingle Pancreatic Panniculitis – case report
Tavares, Ermelindo Silva
title_short Pancreatic Panniculitis – case report
title_full Pancreatic Panniculitis – case report
title_fullStr Pancreatic Panniculitis – case report
title_full_unstemmed Pancreatic Panniculitis – case report
title_sort Pancreatic Panniculitis – case report
author Tavares, Ermelindo Silva
author_facet Tavares, Ermelindo Silva
Parente, Joana Alexandra Devesa
Vera-Cruz, Frederico Pinto
Lima, José Nunes
Aranha, João Manuel Pires
Estrela, António Pedro Fernandes
author_role author
author2 Parente, Joana Alexandra Devesa
Vera-Cruz, Frederico Pinto
Lima, José Nunes
Aranha, João Manuel Pires
Estrela, António Pedro Fernandes
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Tavares, Ermelindo Silva
Parente, Joana Alexandra Devesa
Vera-Cruz, Frederico Pinto
Lima, José Nunes
Aranha, João Manuel Pires
Estrela, António Pedro Fernandes
description A 65-years-old female admitted on general surgery with acute pancreatitis, complicated with painful, erythematous and subcutaneous nodules, located on the legs, followed by poliarthritis. The combination of clinical and laboratory data as well as the results of skin biopsy confirmed the diagnosis of pancreatic panniculitis. The patient was treated with conservative therapy only led to her underlying pathology. A successful outcome and disappearance of the lesions were registered. Pancreatic panniculitis is a rare disorder that affects a small number of patients with pancreatic disorders, particularly pancreatitis (acute and chronic) and carcinoma of the pancreas. The disease is characterized by necrosis of subcutaneous adipose tissue and manifests itself usually by subcutaneous, erythematous and painful nodules, located preferentially on the lower limbs, and in more than half of the cases, there is inflammation of the periarticular fat. In the most cases, histopathology reveals lobular panniculitis and fat cells without nuclei (ghost cells). Treatment is conservative, aimed at the underlying pathology. Keywords: acute pancreatitis, pancreatic carcinoma, panniculitis, ghost cells. 
publishDate 2010
dc.date.none.fl_str_mv 2010-12-29
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://revista.spcir.com/index.php/spcir/article/view/118
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dc.relation.none.fl_str_mv https://revista.spcir.com/index.php/spcir/article/view/118
https://revista.spcir.com/index.php/spcir/article/view/118/116
dc.rights.driver.fl_str_mv Copyright (c) 2016 Revista Portuguesa de Cirurgia
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2016 Revista Portuguesa de Cirurgia
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Cirurgia
publisher.none.fl_str_mv Sociedade Portuguesa de Cirurgia
dc.source.none.fl_str_mv Revista Portuguesa de Cirurgia; No 15 (2010): Dezembro 2010 - II Série; 31-34
Revista Portuguesa de Cirurgia; No 15 (2010): Dezembro 2010 - II Série; 31-34
2183-1165
1646-6918
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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