Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara

Detalhes bibliográficos
Autor(a) principal: Salgado, C
Data de Publicação: 2017
Outros Autores: Garcia, AM, Rúbio, C, Cunha, F
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/2963
Resumo: Infectious mononucleosis is one of the major clinical manifestations of Epstein-Barr virus infection. In this syndrome, elevation of liver transaminase levels is common but cholestasis is rare, with few cases described in the literature. We present the case of a 14-year-old female adolescent, admitted to the Emergency Room with fever, odynophagia and cervical adenomegaly. She was treated with amoxicillin and two days later he presented with jaundice. The analytical evaluation was compatible with cholestatic hepatitis and abdominal ultrasound revealed hepatosplenomegaly without dilatation of the bile ducts. The diagnosis of Epstein-Barr virus infection was confirmed by the presence of serological markers. This case aims to raise awareness of a rare manifestation of a common infectious agent and, consequently, to the inclusion of acute Epstein-Barr virus infection in the differential diagnosis of pediatric cholestatic hepatitis.
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spelling Mononucleose Infeciosa e Hepatite Colestática: Uma Associação RaraInfectious Mononucleosis and Cholestatic Hepatitis: A Rare AssociationInfectious MononucleosisHepatitisEpstein-Barr Virus InfectionsCholestasisAdolescentCase ReportHDE PEDInfectious mononucleosis is one of the major clinical manifestations of Epstein-Barr virus infection. In this syndrome, elevation of liver transaminase levels is common but cholestasis is rare, with few cases described in the literature. We present the case of a 14-year-old female adolescent, admitted to the Emergency Room with fever, odynophagia and cervical adenomegaly. She was treated with amoxicillin and two days later he presented with jaundice. The analytical evaluation was compatible with cholestatic hepatitis and abdominal ultrasound revealed hepatosplenomegaly without dilatation of the bile ducts. The diagnosis of Epstein-Barr virus infection was confirmed by the presence of serological markers. This case aims to raise awareness of a rare manifestation of a common infectious agent and, consequently, to the inclusion of acute Epstein-Barr virus infection in the differential diagnosis of pediatric cholestatic hepatitis.Centro Editor Livreiro da Ordem dos MédicosRepositório do Centro Hospitalar Universitário de Lisboa Central, EPESalgado, CGarcia, AMRúbio, CCunha, F2018-05-10T08:05:59Z2017-12-292017-12-29T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2963porActa Med Port. 2017 Dec 29;30(12):886-888info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:40:32Zoai:repositorio.chlc.min-saude.pt:10400.17/2963Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:20:16.948723Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
Infectious Mononucleosis and Cholestatic Hepatitis: A Rare Association
title Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
spellingShingle Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
Salgado, C
Infectious Mononucleosis
Hepatitis
Epstein-Barr Virus Infections
Cholestasis
Adolescent
Case Report
HDE PED
title_short Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
title_full Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
title_fullStr Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
title_full_unstemmed Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
title_sort Mononucleose Infeciosa e Hepatite Colestática: Uma Associação Rara
author Salgado, C
author_facet Salgado, C
Garcia, AM
Rúbio, C
Cunha, F
author_role author
author2 Garcia, AM
Rúbio, C
Cunha, F
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Salgado, C
Garcia, AM
Rúbio, C
Cunha, F
dc.subject.por.fl_str_mv Infectious Mononucleosis
Hepatitis
Epstein-Barr Virus Infections
Cholestasis
Adolescent
Case Report
HDE PED
topic Infectious Mononucleosis
Hepatitis
Epstein-Barr Virus Infections
Cholestasis
Adolescent
Case Report
HDE PED
description Infectious mononucleosis is one of the major clinical manifestations of Epstein-Barr virus infection. In this syndrome, elevation of liver transaminase levels is common but cholestasis is rare, with few cases described in the literature. We present the case of a 14-year-old female adolescent, admitted to the Emergency Room with fever, odynophagia and cervical adenomegaly. She was treated with amoxicillin and two days later he presented with jaundice. The analytical evaluation was compatible with cholestatic hepatitis and abdominal ultrasound revealed hepatosplenomegaly without dilatation of the bile ducts. The diagnosis of Epstein-Barr virus infection was confirmed by the presence of serological markers. This case aims to raise awareness of a rare manifestation of a common infectious agent and, consequently, to the inclusion of acute Epstein-Barr virus infection in the differential diagnosis of pediatric cholestatic hepatitis.
publishDate 2017
dc.date.none.fl_str_mv 2017-12-29
2017-12-29T00:00:00Z
2018-05-10T08:05:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/2963
url http://hdl.handle.net/10400.17/2963
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Acta Med Port. 2017 Dec 29;30(12):886-888
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Centro Editor Livreiro da Ordem dos Médicos
publisher.none.fl_str_mv Centro Editor Livreiro da Ordem dos Médicos
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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