NMR-based metabolomics studies of human prostate cancer tissue

Detalhes bibliográficos
Autor(a) principal: Lima, Ana Rita
Data de Publicação: 2018
Outros Autores: Pinto, Joana, Bastos, Maria de Lourdes, Carvalho, Márcia, Guedes de Pinho, Paula
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10284/10018
Resumo: Prostate cancer (PCa) is one of the most prevalent cancers in men worldwide. Serum prostate-specific antigen (PSA) remains the most used biomarker in the detection and management of patients with PCa, in spite of the problems related with its low specificity, false positive rate and overdiagnosis. Furthermore, PSA is unable to discriminate indolent from aggressive PCa, which can lead to overtreatment. Early diagnosed and treated PCa can have a good prognosis and is potentially curable. Therefore, the discovery of new biomarkers able to detect clinically significant aggressive PCa is urgently needed.
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spelling NMR-based metabolomics studies of human prostate cancer tissueProstate cancerMetabolomicsTissuesNuclear magnetic resonance spectroscopyProstate cancer (PCa) is one of the most prevalent cancers in men worldwide. Serum prostate-specific antigen (PSA) remains the most used biomarker in the detection and management of patients with PCa, in spite of the problems related with its low specificity, false positive rate and overdiagnosis. Furthermore, PSA is unable to discriminate indolent from aggressive PCa, which can lead to overtreatment. Early diagnosed and treated PCa can have a good prognosis and is potentially curable. Therefore, the discovery of new biomarkers able to detect clinically significant aggressive PCa is urgently needed.SpringerRepositório Institucional da Universidade Fernando PessoaLima, Ana RitaPinto, JoanaBastos, Maria de LourdesCarvalho, MárciaGuedes de Pinho, Paula2021-07-02T11:10:32Z2018-01-01T00:00:00Z2018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10284/10018eng1573-388210.1007/s11306-018-1384-2metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-06T02:09:18Zoai:bdigital.ufp.pt:10284/10018Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:46:47.595429Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv NMR-based metabolomics studies of human prostate cancer tissue
title NMR-based metabolomics studies of human prostate cancer tissue
spellingShingle NMR-based metabolomics studies of human prostate cancer tissue
Lima, Ana Rita
Prostate cancer
Metabolomics
Tissues
Nuclear magnetic resonance spectroscopy
title_short NMR-based metabolomics studies of human prostate cancer tissue
title_full NMR-based metabolomics studies of human prostate cancer tissue
title_fullStr NMR-based metabolomics studies of human prostate cancer tissue
title_full_unstemmed NMR-based metabolomics studies of human prostate cancer tissue
title_sort NMR-based metabolomics studies of human prostate cancer tissue
author Lima, Ana Rita
author_facet Lima, Ana Rita
Pinto, Joana
Bastos, Maria de Lourdes
Carvalho, Márcia
Guedes de Pinho, Paula
author_role author
author2 Pinto, Joana
Bastos, Maria de Lourdes
Carvalho, Márcia
Guedes de Pinho, Paula
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Institucional da Universidade Fernando Pessoa
dc.contributor.author.fl_str_mv Lima, Ana Rita
Pinto, Joana
Bastos, Maria de Lourdes
Carvalho, Márcia
Guedes de Pinho, Paula
dc.subject.por.fl_str_mv Prostate cancer
Metabolomics
Tissues
Nuclear magnetic resonance spectroscopy
topic Prostate cancer
Metabolomics
Tissues
Nuclear magnetic resonance spectroscopy
description Prostate cancer (PCa) is one of the most prevalent cancers in men worldwide. Serum prostate-specific antigen (PSA) remains the most used biomarker in the detection and management of patients with PCa, in spite of the problems related with its low specificity, false positive rate and overdiagnosis. Furthermore, PSA is unable to discriminate indolent from aggressive PCa, which can lead to overtreatment. Early diagnosed and treated PCa can have a good prognosis and is potentially curable. Therefore, the discovery of new biomarkers able to detect clinically significant aggressive PCa is urgently needed.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01T00:00:00Z
2018-01-01T00:00:00Z
2021-07-02T11:10:32Z
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url http://hdl.handle.net/10284/10018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1573-3882
10.1007/s11306-018-1384-2
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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