Morphological transition of Helicobacter pylori adapted to water
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/1822/46936 |
Resumo: | To view the supplementary data that accompany this paper please visit the journal website at: www. futuremedicine.com /doi/full/10.2217/fmb-2016-0174. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Morphological transition of Helicobacter pylori adapted to waterHelicobacter pyloriAdaptationMorphological transitionPeptidoglycanWaterScience & TechnologyTo view the supplementary data that accompany this paper please visit the journal website at: www. futuremedicine.com /doi/full/10.2217/fmb-2016-0174.Aim: This study aims to investigate the morphological transition of Helicobacter pylori during adaptation to water. Materials \& methods: Different strains were adapted to water. Changes regarding cultivability and cellular morphology were recorded. Expression of 11 genes involved in H. pylori morphological changes was evaluated by real-time PCR. Results: H. pylori presented increased cultivability in water after adaptation. The permanent loss of the spiral shape was observed, but no transition into coccoid form has occurred. Expression levels of genes involved in peptidoglycan assembly of H. pylori 26695 have shown significant changes between adapted and nonadapted strains. Conclusion: Adaption to water favors the culturable phenotype and the morphological transition to the rod shape, into a process that implicates the peptidoglycan turnover.This work was supported by the Portuguese Foundation for Science and Technology (FCT) under the project ‘Heliwater’ (PTDC/BIA-MIC/108811/2008), the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020 – Programa Operacional Regional do Norte. No writing assistance was utilized in the production of this manuscript.info:eu-repo/semantics/publishedVersionFuture Medicine LtdUniversidade do MinhoFernandes, R.Silva, H.Oliveira, RicardoAlmeida, CarinaAzevedo, N. F.Vieira, Maria João2017-09-072017-09-07T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/46936engFernandes, R.; Silva, H.; Oliveira, R.; Almeida, Carina; Azevedo, N. F.; Vieira, Maria João, Morphological transition of Helicobacter pylori adapted to water. Future Microbiology, 12(13), 1167-1179, 20171746-09131746-092110.2217/fmb-2016-017428879777http://www.futuremedicine.com/loi/fmbinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:03:02Zoai:repositorium.sdum.uminho.pt:1822/46936Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:53:06.978066Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Morphological transition of Helicobacter pylori adapted to water |
| title |
Morphological transition of Helicobacter pylori adapted to water |
| spellingShingle |
Morphological transition of Helicobacter pylori adapted to water Fernandes, R. Helicobacter pylori Adaptation Morphological transition Peptidoglycan Water Science & Technology |
| title_short |
Morphological transition of Helicobacter pylori adapted to water |
| title_full |
Morphological transition of Helicobacter pylori adapted to water |
| title_fullStr |
Morphological transition of Helicobacter pylori adapted to water |
| title_full_unstemmed |
Morphological transition of Helicobacter pylori adapted to water |
| title_sort |
Morphological transition of Helicobacter pylori adapted to water |
| author |
Fernandes, R. |
| author_facet |
Fernandes, R. Silva, H. Oliveira, Ricardo Almeida, Carina Azevedo, N. F. Vieira, Maria João |
| author_role |
author |
| author2 |
Silva, H. Oliveira, Ricardo Almeida, Carina Azevedo, N. F. Vieira, Maria João |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade do Minho |
| dc.contributor.author.fl_str_mv |
Fernandes, R. Silva, H. Oliveira, Ricardo Almeida, Carina Azevedo, N. F. Vieira, Maria João |
| dc.subject.por.fl_str_mv |
Helicobacter pylori Adaptation Morphological transition Peptidoglycan Water Science & Technology |
| topic |
Helicobacter pylori Adaptation Morphological transition Peptidoglycan Water Science & Technology |
| description |
To view the supplementary data that accompany this paper please visit the journal website at: www. futuremedicine.com /doi/full/10.2217/fmb-2016-0174. |
| publishDate |
2017 |
| dc.date.none.fl_str_mv |
2017-09-07 2017-09-07T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/46936 |
| url |
http://hdl.handle.net/1822/46936 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Fernandes, R.; Silva, H.; Oliveira, R.; Almeida, Carina; Azevedo, N. F.; Vieira, Maria João, Morphological transition of Helicobacter pylori adapted to water. Future Microbiology, 12(13), 1167-1179, 2017 1746-0913 1746-0921 10.2217/fmb-2016-0174 28879777 http://www.futuremedicine.com/loi/fmb |
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info:eu-repo/semantics/openAccess |
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openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Future Medicine Ltd |
| publisher.none.fl_str_mv |
Future Medicine Ltd |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132309311455232 |