In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/20584 |
Resumo: | The present work investigates, in situ, the in vitro bioactivity of partially crystallized 45S5 Bioglass! (BG) as a function of immersion time in a simulated body fluid (SBF) using atomic force microscopy (AFM). The results obtained for the crystallized BG! were compared to those of hydroxyapatite c- and a-faces. The calcium phosphate layer grows on the crystallized 45S5 B! by multiple two-dimensional nucleation and fusion of these two-dimensional islands, which is essentially the same mode as for the hydroxyapatite c-face. The surface of the crystallized 45S5 BG! was almost fully covered with a dense and compact calcium phosphate layer after 24 h. The calcium phosphate formation on the crystallized BG! arises from a low surface energy of the surface layer and/or an effect of the layer to lower the resistance when the growth units of calcium phosphate incorporate into the growing island. These results indicate that the crystallized 45S5 BG! is suitable to be used as a filler for polymeric matrix bioactive composites, as it maintains a high bioactivity associated with a stiffer behavior (as compared to standard BG!). |
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In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopyBioglassAtomic force microscopyIn situIn vitroBioactivityBioglass (R)Science & TechnologyThe present work investigates, in situ, the in vitro bioactivity of partially crystallized 45S5 Bioglass! (BG) as a function of immersion time in a simulated body fluid (SBF) using atomic force microscopy (AFM). The results obtained for the crystallized BG! were compared to those of hydroxyapatite c- and a-faces. The calcium phosphate layer grows on the crystallized 45S5 B! by multiple two-dimensional nucleation and fusion of these two-dimensional islands, which is essentially the same mode as for the hydroxyapatite c-face. The surface of the crystallized 45S5 BG! was almost fully covered with a dense and compact calcium phosphate layer after 24 h. The calcium phosphate formation on the crystallized BG! arises from a low surface energy of the surface layer and/or an effect of the layer to lower the resistance when the growth units of calcium phosphate incorporate into the growing island. These results indicate that the crystallized 45S5 BG! is suitable to be used as a filler for polymeric matrix bioactive composites, as it maintains a high bioactivity associated with a stiffer behavior (as compared to standard BG!).WileyUniversidade do MinhoLeonor, I. B.Ito, A.Onuma, K.Kanzaki, N.Zhong, Z. P.Greenspan, D.Reis, R. L.20022002-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/20584eng0021-930410.1002/jbm.1028912124789info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:17:03Zoai:repositorium.sdum.uminho.pt:1822/20584Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:09:37.060531Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy |
title |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy |
spellingShingle |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy Leonor, I. B. Bioglass Atomic force microscopy In situ In vitro Bioactivity Bioglass (R) Science & Technology |
title_short |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy |
title_full |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy |
title_fullStr |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy |
title_full_unstemmed |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy |
title_sort |
In situ study of partially crystallized bioglass (R) and hydroxylapatite in vitro bioactivity using atomic force microscopy |
author |
Leonor, I. B. |
author_facet |
Leonor, I. B. Ito, A. Onuma, K. Kanzaki, N. Zhong, Z. P. Greenspan, D. Reis, R. L. |
author_role |
author |
author2 |
Ito, A. Onuma, K. Kanzaki, N. Zhong, Z. P. Greenspan, D. Reis, R. L. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Leonor, I. B. Ito, A. Onuma, K. Kanzaki, N. Zhong, Z. P. Greenspan, D. Reis, R. L. |
dc.subject.por.fl_str_mv |
Bioglass Atomic force microscopy In situ In vitro Bioactivity Bioglass (R) Science & Technology |
topic |
Bioglass Atomic force microscopy In situ In vitro Bioactivity Bioglass (R) Science & Technology |
description |
The present work investigates, in situ, the in vitro bioactivity of partially crystallized 45S5 Bioglass! (BG) as a function of immersion time in a simulated body fluid (SBF) using atomic force microscopy (AFM). The results obtained for the crystallized BG! were compared to those of hydroxyapatite c- and a-faces. The calcium phosphate layer grows on the crystallized 45S5 B! by multiple two-dimensional nucleation and fusion of these two-dimensional islands, which is essentially the same mode as for the hydroxyapatite c-face. The surface of the crystallized 45S5 BG! was almost fully covered with a dense and compact calcium phosphate layer after 24 h. The calcium phosphate formation on the crystallized BG! arises from a low surface energy of the surface layer and/or an effect of the layer to lower the resistance when the growth units of calcium phosphate incorporate into the growing island. These results indicate that the crystallized 45S5 BG! is suitable to be used as a filler for polymeric matrix bioactive composites, as it maintains a high bioactivity associated with a stiffer behavior (as compared to standard BG!). |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002 2002-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/20584 |
url |
http://hdl.handle.net/1822/20584 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0021-9304 10.1002/jbm.10289 12124789 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132522247880704 |