Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults?
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2020000300009 |
Resumo: | Introduction: Acute respiratory failure (ARF) is one of the most prevalent causes of observation in the emergency department in an ageing population. Non-invasive positive pressure ventilation (NIPPV) has shown good results in critically ill with ARF. The evidence of NIPPV outcomes in old patients is scarce. The aim of our study is to analyse outcomes of NIPPV use in this population. Methods: We conducted a prospective observational study in a 12-bed intermediate care unit of an university hospital. We included and consecutively compared patients aged 75 years old or more (study group) and under 65 years old (control group) submitted to NIPPV due to ARF. The primary end point was mortality (in-hospital and 30 daysafter discharge). Secondary endpoints were NIPPV settings, complications, and failure rate. Results: A total of 109 patients were included. In-hospital mortality was significantly higher in the study group (22.2 % vs 8.1%, p< 0.01). However, mortality 30 days after discharge was not significantly different (4.1% vs 4.9%, p = 0.37). NIPPV duration of use (6.1 vs 2.2 days, p < 0.01) and hospital length of stay (14.3 vs 6.2 days, p = 0.01) were higher in the study group. NIPPV failure (22.2% vs 16.1 %, p = 0.09) and complication rate (intolerance 8% vs 6%, p = 0.31; ulcers 4% vs 3%, p = 0.28) were similar in both groups. Conclusion: ARF carries a grim prognosis in older adults. A high mortality rate was observed in older patients despite similar severity assessments and NIPPV failure and complication rates. Notably, out of the hospital mortality is comparable between both groups. |
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Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults?AgedAged, 80 and overNoninvasive VentilationRespiratory InsufficiencyTreatment FailureIntroduction: Acute respiratory failure (ARF) is one of the most prevalent causes of observation in the emergency department in an ageing population. Non-invasive positive pressure ventilation (NIPPV) has shown good results in critically ill with ARF. The evidence of NIPPV outcomes in old patients is scarce. The aim of our study is to analyse outcomes of NIPPV use in this population. Methods: We conducted a prospective observational study in a 12-bed intermediate care unit of an university hospital. We included and consecutively compared patients aged 75 years old or more (study group) and under 65 years old (control group) submitted to NIPPV due to ARF. The primary end point was mortality (in-hospital and 30 daysafter discharge). Secondary endpoints were NIPPV settings, complications, and failure rate. Results: A total of 109 patients were included. In-hospital mortality was significantly higher in the study group (22.2 % vs 8.1%, p< 0.01). However, mortality 30 days after discharge was not significantly different (4.1% vs 4.9%, p = 0.37). NIPPV duration of use (6.1 vs 2.2 days, p < 0.01) and hospital length of stay (14.3 vs 6.2 days, p = 0.01) were higher in the study group. NIPPV failure (22.2% vs 16.1 %, p = 0.09) and complication rate (intolerance 8% vs 6%, p = 0.31; ulcers 4% vs 3%, p = 0.28) were similar in both groups. Conclusion: ARF carries a grim prognosis in older adults. A high mortality rate was observed in older patients despite similar severity assessments and NIPPV failure and complication rates. Notably, out of the hospital mortality is comparable between both groups.Sociedade Portuguesa de Medicina Interna2020-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2020000300009Medicina Interna v.27 n.2 2020reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2020000300009Costa,Ana RitaFrutado,InêsGonçalves,JoãoMeireles,MarianaNeves,JoãoMateus,Andreainfo:eu-repo/semantics/openAccess2023-07-27T12:24:01ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? |
title |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? |
spellingShingle |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? Costa,Ana Rita Aged Aged, 80 and over Noninvasive Ventilation Respiratory Insufficiency Treatment Failure |
title_short |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? |
title_full |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? |
title_fullStr |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? |
title_full_unstemmed |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? |
title_sort |
Are Outcomes of Non-Invasive Ventilation in Acute Respiratory Failure Similar in Very Old Adults? |
author |
Costa,Ana Rita |
author_facet |
Costa,Ana Rita Frutado,Inês Gonçalves,João Meireles,Mariana Neves,João Mateus,Andrea |
author_role |
author |
author2 |
Frutado,Inês Gonçalves,João Meireles,Mariana Neves,João Mateus,Andrea |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Costa,Ana Rita Frutado,Inês Gonçalves,João Meireles,Mariana Neves,João Mateus,Andrea |
dc.subject.por.fl_str_mv |
Aged Aged, 80 and over Noninvasive Ventilation Respiratory Insufficiency Treatment Failure |
topic |
Aged Aged, 80 and over Noninvasive Ventilation Respiratory Insufficiency Treatment Failure |
description |
Introduction: Acute respiratory failure (ARF) is one of the most prevalent causes of observation in the emergency department in an ageing population. Non-invasive positive pressure ventilation (NIPPV) has shown good results in critically ill with ARF. The evidence of NIPPV outcomes in old patients is scarce. The aim of our study is to analyse outcomes of NIPPV use in this population. Methods: We conducted a prospective observational study in a 12-bed intermediate care unit of an university hospital. We included and consecutively compared patients aged 75 years old or more (study group) and under 65 years old (control group) submitted to NIPPV due to ARF. The primary end point was mortality (in-hospital and 30 daysafter discharge). Secondary endpoints were NIPPV settings, complications, and failure rate. Results: A total of 109 patients were included. In-hospital mortality was significantly higher in the study group (22.2 % vs 8.1%, p< 0.01). However, mortality 30 days after discharge was not significantly different (4.1% vs 4.9%, p = 0.37). NIPPV duration of use (6.1 vs 2.2 days, p < 0.01) and hospital length of stay (14.3 vs 6.2 days, p = 0.01) were higher in the study group. NIPPV failure (22.2% vs 16.1 %, p = 0.09) and complication rate (intolerance 8% vs 6%, p = 0.31; ulcers 4% vs 3%, p = 0.28) were similar in both groups. Conclusion: ARF carries a grim prognosis in older adults. A high mortality rate was observed in older patients despite similar severity assessments and NIPPV failure and complication rates. Notably, out of the hospital mortality is comparable between both groups. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-04-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2020000300009 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2020000300009 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-671X2020000300009 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Medicina Interna |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Medicina Interna |
dc.source.none.fl_str_mv |
Medicina Interna v.27 n.2 2020 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
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repository.mail.fl_str_mv |
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1777304410361167872 |