A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.34635/rpc.938 |
Resumo: | Introduction: Prehabilitation is a multimodal strategy implemented in the preoperative period, aiming to increase preoperative functional reserve, leading to better postoperative functional recovery and reduced incidence of complications. The majority of the prehabiliation programs are developed under supervision in an outpatient clinic, which might be an obstacle for those patients with geographical and/or travelling constrains. Home-based programs, with the support of telehealth resources, could be a convenient way to surpass these barriers. Methods: Patients with locally advanced, potentially resectable gastric or GEJ adenocarcinoma, undergoing perioperative chemotherapy with FLOT regimen will be recruited at IPO-Porto and Hospital Garcia de Orta. Patient will be invited to undergo a prehabilitation program (PREHAB) in addition to their usual (medical optimization, nutritional and psychological care). Exercise intervention will comprise aerobic and resistance training. An internet-based platform (iTerapy) via computer or mobile devices, will be used to deliver and monitor the intervention. The primary outcome of this study is to test the acceptability, feasibility and safety of the intervention. As secondary outcomes, we intend to assess the impact of home- based prehabilitation on functional capacity, frailty status, quality of life, disability, postoperative complications and mortality, length of hospital stay, need of ICU, hospital readmission and place of discharge. Conclusion: This study will inform for a future randomized clinical trial to assess the role of prehabilitation to reduce postoperative morbidity and mortality in this population. |
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A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITYUM PROGRAMA DE PRÉ-HABILITAÇÃO DOMICILIAR, APLICADO ATRAVÉS DE UMA PLATAFORMA BASEADA NA INTERNET, EM DOENTES COM ADENOCARCINOMA LOCALMENTE AVANÇADO DA JUNÇÃO GASTROESOFÁGICA E ESTÔMAGO, ELEGÍVEIS PARA QUIMIOTERAPIA PERIOPERATÓRIA: PROTOCOLO PARA ESTUDO DIntroduction: Prehabilitation is a multimodal strategy implemented in the preoperative period, aiming to increase preoperative functional reserve, leading to better postoperative functional recovery and reduced incidence of complications. The majority of the prehabiliation programs are developed under supervision in an outpatient clinic, which might be an obstacle for those patients with geographical and/or travelling constrains. Home-based programs, with the support of telehealth resources, could be a convenient way to surpass these barriers. Methods: Patients with locally advanced, potentially resectable gastric or GEJ adenocarcinoma, undergoing perioperative chemotherapy with FLOT regimen will be recruited at IPO-Porto and Hospital Garcia de Orta. Patient will be invited to undergo a prehabilitation program (PREHAB) in addition to their usual (medical optimization, nutritional and psychological care). Exercise intervention will comprise aerobic and resistance training. An internet-based platform (iTerapy) via computer or mobile devices, will be used to deliver and monitor the intervention. The primary outcome of this study is to test the acceptability, feasibility and safety of the intervention. As secondary outcomes, we intend to assess the impact of home- based prehabilitation on functional capacity, frailty status, quality of life, disability, postoperative complications and mortality, length of hospital stay, need of ICU, hospital readmission and place of discharge. Conclusion: This study will inform for a future randomized clinical trial to assess the role of prehabilitation to reduce postoperative morbidity and mortality in this population.Introdução: A pré-habilitação corresponde a uma intervenção multimodal, implementada no período pré-operatório, com o objetivo de aumentar a reserva funcional pré-operatória, acelerar a recuperação funcional pós-operatória e reduzir da incidência de complicações. A maioria dos programas de pré-habitabilitação é desenvolvida sob supervisão médica em ambulatório, o que pode ser um obstáculo para aqueles doentes com restrições geográficas e / ou de transporte. Programas domiciliares, com o apoio a recursos de telemedicina, poderão ser uma estratégica conveniente de superar essas barreiras. Métodos: Doentes com adenocarcinoma gástrico ou junção gastroesofágica localmente avançado, potencialmente ressecável, em quimioterapia perioperatória com regime FLOT serão recrutados no IPO-Porto e no Hospital Garcia de Orta. Os participantes serão convidados a realizar um programa de pré-habilitação com exercício físico (PREHAB) complementar aos cuidados habituais (otimização médica, atendimento nutricional e psicológico). A intervenção com exercício físico incluirá treino combinado (exercício aeróbio e resistido) e treino dos músculos inspiratórios. Uma plataforma digital (iTherapy), acessível via computador ou dispositivos móveis, será utilizada para implementar e monitorizar a intervenção. O objetivo principal deste estudo é testar a aceitabilidade, viabilidade e segurança da intervenção. Como objetivos secundários, pretendemos avaliar o impacto da pré-habilitação domiciliar na capacidade funcional, estado de fragilidade, qualidade de vida, incapacidade, complicações pós-operatórias e mortalidade, tempo de hospitalização, necessidade de UCI, readmissão hospitalar e local de alta. Conclusão: Este estudo servirá de base para um futuro ensaio clínico randomizado para avaliar o papel da pré-habilitação na redução da morbimortalidade pós-operatória nesta população.Sociedade Portuguesa de Cirurgia2022-02-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.34635/rpc.938https://doi.org/10.34635/rpc.938Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 125-136Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 125-1362183-11651646-6918reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spcir.com/index.php/spcir/article/view/938https://revista.spcir.com/index.php/spcir/article/view/938/625Copyright (c) 2021 Revista Portuguesa de Cirurgiainfo:eu-repo/semantics/openAccessMoreira-Gonçalves, Danieldo Vale Fernandes, AnteroDaher Mota, ClaraAntunes, JoãoCanappele, CarinaMartins, PedroSantos, FátimaCabral, SóniaCastro, CarolinaMendes Santos, CristinaAlmeida, SusanaRodrigues, JéssicaRomano, OtíliaFonseca, Ana SofiaLages, PatríciaMatos Costa, PauloLara Santos, Lúcio2024-03-14T22:05:26Zoai:revista.spcir.com:article/938Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T04:00:54.393737Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY UM PROGRAMA DE PRÉ-HABILITAÇÃO DOMICILIAR, APLICADO ATRAVÉS DE UMA PLATAFORMA BASEADA NA INTERNET, EM DOENTES COM ADENOCARCINOMA LOCALMENTE AVANÇADO DA JUNÇÃO GASTROESOFÁGICA E ESTÔMAGO, ELEGÍVEIS PARA QUIMIOTERAPIA PERIOPERATÓRIA: PROTOCOLO PARA ESTUDO D |
title |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY |
spellingShingle |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY Moreira-Gonçalves, Daniel |
title_short |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY |
title_full |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY |
title_fullStr |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY |
title_full_unstemmed |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY |
title_sort |
A HOME-BASED PREHABILITATION PROGRAM, DELIVERED THROUGH AN INTERNET-BASED PLATFORM, IN PATIENTS WITH LOCALLY ADVANCED GASTROESOPHAGEAL JUNCTION AND STOMACH ADENOCARCINOMA, UNDERGOING PERIOPERATIVE CHEMOTHERAPY: PROTOCOL FOR A FEASIBILITY AND ACCEPTABILITY |
author |
Moreira-Gonçalves, Daniel |
author_facet |
Moreira-Gonçalves, Daniel do Vale Fernandes, Antero Daher Mota, Clara Antunes, João Canappele, Carina Martins, Pedro Santos, Fátima Cabral, Sónia Castro, Carolina Mendes Santos, Cristina Almeida, Susana Rodrigues, Jéssica Romano, Otília Fonseca, Ana Sofia Lages, Patrícia Matos Costa, Paulo Lara Santos, Lúcio |
author_role |
author |
author2 |
do Vale Fernandes, Antero Daher Mota, Clara Antunes, João Canappele, Carina Martins, Pedro Santos, Fátima Cabral, Sónia Castro, Carolina Mendes Santos, Cristina Almeida, Susana Rodrigues, Jéssica Romano, Otília Fonseca, Ana Sofia Lages, Patrícia Matos Costa, Paulo Lara Santos, Lúcio |
author2_role |
author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Moreira-Gonçalves, Daniel do Vale Fernandes, Antero Daher Mota, Clara Antunes, João Canappele, Carina Martins, Pedro Santos, Fátima Cabral, Sónia Castro, Carolina Mendes Santos, Cristina Almeida, Susana Rodrigues, Jéssica Romano, Otília Fonseca, Ana Sofia Lages, Patrícia Matos Costa, Paulo Lara Santos, Lúcio |
description |
Introduction: Prehabilitation is a multimodal strategy implemented in the preoperative period, aiming to increase preoperative functional reserve, leading to better postoperative functional recovery and reduced incidence of complications. The majority of the prehabiliation programs are developed under supervision in an outpatient clinic, which might be an obstacle for those patients with geographical and/or travelling constrains. Home-based programs, with the support of telehealth resources, could be a convenient way to surpass these barriers. Methods: Patients with locally advanced, potentially resectable gastric or GEJ adenocarcinoma, undergoing perioperative chemotherapy with FLOT regimen will be recruited at IPO-Porto and Hospital Garcia de Orta. Patient will be invited to undergo a prehabilitation program (PREHAB) in addition to their usual (medical optimization, nutritional and psychological care). Exercise intervention will comprise aerobic and resistance training. An internet-based platform (iTerapy) via computer or mobile devices, will be used to deliver and monitor the intervention. The primary outcome of this study is to test the acceptability, feasibility and safety of the intervention. As secondary outcomes, we intend to assess the impact of home- based prehabilitation on functional capacity, frailty status, quality of life, disability, postoperative complications and mortality, length of hospital stay, need of ICU, hospital readmission and place of discharge. Conclusion: This study will inform for a future randomized clinical trial to assess the role of prehabilitation to reduce postoperative morbidity and mortality in this population. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-02-03 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.34635/rpc.938 https://doi.org/10.34635/rpc.938 |
url |
https://doi.org/10.34635/rpc.938 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revista.spcir.com/index.php/spcir/article/view/938 https://revista.spcir.com/index.php/spcir/article/view/938/625 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Revista Portuguesa de Cirurgia info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 Revista Portuguesa de Cirurgia |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Cirurgia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Cirurgia |
dc.source.none.fl_str_mv |
Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 125-136 Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 125-136 2183-1165 1646-6918 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799138183312572416 |