Acne Vulgaris in Adults
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.76.3.953 |
Resumo: | Introduction: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, of multifactorial etiology. It is one of the most common dermatological diseases. It affects more than 85% of teenagers, especially of the male gender. Despite being infrequent in adulthood, recent epidemiological data show a growing prevalence, around 40%, mainly in the female gender, with a negative impact on quality of life. Acne in adulthood or late acne is present after the age of 25 and is classified as late onset acne or persistent acne. The persistent type, which is the most common, represents 70% - 80% of all cases, and is characterised by the persistence of the teenage acne, while late onset acne is defined by the onset after the age of 25, with a prevalence of about 20% to 30%.Objective: To review current scientific literature, especially focused on the pathophysiology of late acne, triggering and aggravating factors, as well as particularities of the therapeutic approach.Methodology: The MEDLINE-PubMed database was used to select original and review articles published between 2001 and 2017.Discussion: Acne can be a clinical sign of systemic disease, mainly with endocrinological abnormalities, as polycystic ovary syndrome, adrenal hyperplasia and virilising tumours. It is important to consider these etiologies into account, especially in women and in the presence of other signs of hyperandrogenism. Several studies point to other triggering or aggravating factors, namely genetic factors, stress, smoking, exposure to ultraviolet radiation, obesity, hyperglycaemic diet, drugs, cosmetics and colonisation by resistant strains of Propionibacterium acnes.Conclusion: In most cases, adult acne affects the face, has mild to moderate clinical severity and is associated with normal hormonal levels. The exclusive location on the lower third of the face is most often associated with other signs of hyperandrogenism and endocrinological disease, as well as with a predominance of inflammatory lesions. Late acne is described as potentially refractory to the conventional therapy and is very relapsing. Thus, it is a therapeutic challenge, which requires an individualized approach. |
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Acne Vulgaris in AdultsAcne Vulgar no AdultoAcne Vulgaris/epidemiologyAcne Vulgaris/etiologyAcne Vulgaris/physiopathologyAcne Vulgaris/therapyAdultoAcne vulgarisacne no adultofatores desencadeantes/agravanteshiperandrogenismoacne refratáriaterapêutica hormonal.Introduction: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, of multifactorial etiology. It is one of the most common dermatological diseases. It affects more than 85% of teenagers, especially of the male gender. Despite being infrequent in adulthood, recent epidemiological data show a growing prevalence, around 40%, mainly in the female gender, with a negative impact on quality of life. Acne in adulthood or late acne is present after the age of 25 and is classified as late onset acne or persistent acne. The persistent type, which is the most common, represents 70% - 80% of all cases, and is characterised by the persistence of the teenage acne, while late onset acne is defined by the onset after the age of 25, with a prevalence of about 20% to 30%.Objective: To review current scientific literature, especially focused on the pathophysiology of late acne, triggering and aggravating factors, as well as particularities of the therapeutic approach.Methodology: The MEDLINE-PubMed database was used to select original and review articles published between 2001 and 2017.Discussion: Acne can be a clinical sign of systemic disease, mainly with endocrinological abnormalities, as polycystic ovary syndrome, adrenal hyperplasia and virilising tumours. It is important to consider these etiologies into account, especially in women and in the presence of other signs of hyperandrogenism. Several studies point to other triggering or aggravating factors, namely genetic factors, stress, smoking, exposure to ultraviolet radiation, obesity, hyperglycaemic diet, drugs, cosmetics and colonisation by resistant strains of Propionibacterium acnes.Conclusion: In most cases, adult acne affects the face, has mild to moderate clinical severity and is associated with normal hormonal levels. The exclusive location on the lower third of the face is most often associated with other signs of hyperandrogenism and endocrinological disease, as well as with a predominance of inflammatory lesions. Late acne is described as potentially refractory to the conventional therapy and is very relapsing. Thus, it is a therapeutic challenge, which requires an individualized approach.Introdução: A acne vulgar é uma doença inflamatória crónica da unidade pilossebácea, de etiologia multifatorial. Trata-se de uma das doenças dermatológicas mais comuns. Afeta mais de 85% dos adolescentes, especialmente do género masculino. Apesar de infrequente na idade adulta, dados epidemiológicos recentes mostram uma prevalência crescente, cerca de 40%, predominantemente no género feminino, com impacto negativo na qualidade de vida. A acne do adulto ou acne tardia é uma entidade que está presente após os 25 anos de idade. Classifica-se como acne de início tardio e acne persistente. O tipo persistente é o mais comum, representando 70% a 80% dos casos, e caracteriza-se pela persistência da acne da adolescência, enquanto que a acne de início tardio é definida pela manifestação inaugural após os 25 anos de idade, com uma prevalência de cerca de 20% a 30%.Objetivo: Revisão bibliográfica da literatura científica atual, especialmente focada na fisiopatologia da acne tardia, fatores desencadeantes e agravantes, bem como nas particularidades da sua abordagem terapêutica.Metodologia: Foi utilizada a base de dados MEDLINE-PubMed e foram revistos artigos originais e de revisão bibliográfica publicados entre 2001 e 2017.Discussão: A acne pode ser uma manifestação clínica de doença sistémica, frequentemente endocrinológica, como síndrome do ovário poliquístico, hiperplasia suprarrenal, e tumores secretores virilizantes. É importante considerar estas etiologias, especialmente na mulher e na presença de outros sinais de hiperandrogenismo. Vários estudos apontam outros fatores desencadeantes ou agravantes, nomeadamente fatores genéticos, stress, tabagismo, exposição à radiação ultravioleta, obesidade, dieta hiperglicémica, fármacos, cosméticos, e colonização por estirpes resistentes de Propionibacterium acnes.Conclusão: Na maioria dos casos, a acne do adulto localiza-se na face, tem uma gravidade clínica ligeira a moderada e cursa com níveis hormonais normais. A localização exclusiva no terço inferior da face associa-se mais frequentemente a outros sinais de hiperandrogenismo e a patologia endocrinológica, bem como a um predomínio de lesões inflamatórias. A acne tardia é descrita como potencialmente refratária à terapêutica convencional, sendo muito recidivante. Assim, constitui um desafio terapêutico, que obriga a uma abordagem individualizada.Sociedade Portuguesa de Dermatologia e Venereologia2018-10-05T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.76.3.953oai:ojs.revista.spdv.com.pt:article/953Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 3 (2018): July - September; 299-312Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 3 (2018): Julho - Setembro; 299-3122182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/953https://doi.org/10.29021/spdv.76.3.953https://revista.spdv.com.pt/index.php/spdv/article/view/953/586Vieira da Costa, InêsCardoso da Cunha Velho, Glória Mariainfo:eu-repo/semantics/openAccess2022-10-06T12:35:09ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Acne Vulgaris in Adults Acne Vulgar no Adulto |
title |
Acne Vulgaris in Adults |
spellingShingle |
Acne Vulgaris in Adults Vieira da Costa, Inês Acne Vulgaris/epidemiology Acne Vulgaris/etiology Acne Vulgaris/physiopathology Acne Vulgaris/therapy Adulto Acne vulgaris acne no adulto fatores desencadeantes/agravantes hiperandrogenismo acne refratária terapêutica hormonal. |
title_short |
Acne Vulgaris in Adults |
title_full |
Acne Vulgaris in Adults |
title_fullStr |
Acne Vulgaris in Adults |
title_full_unstemmed |
Acne Vulgaris in Adults |
title_sort |
Acne Vulgaris in Adults |
author |
Vieira da Costa, Inês |
author_facet |
Vieira da Costa, Inês Cardoso da Cunha Velho, Glória Maria |
author_role |
author |
author2 |
Cardoso da Cunha Velho, Glória Maria |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Vieira da Costa, Inês Cardoso da Cunha Velho, Glória Maria |
dc.subject.por.fl_str_mv |
Acne Vulgaris/epidemiology Acne Vulgaris/etiology Acne Vulgaris/physiopathology Acne Vulgaris/therapy Adulto Acne vulgaris acne no adulto fatores desencadeantes/agravantes hiperandrogenismo acne refratária terapêutica hormonal. |
topic |
Acne Vulgaris/epidemiology Acne Vulgaris/etiology Acne Vulgaris/physiopathology Acne Vulgaris/therapy Adulto Acne vulgaris acne no adulto fatores desencadeantes/agravantes hiperandrogenismo acne refratária terapêutica hormonal. |
description |
Introduction: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, of multifactorial etiology. It is one of the most common dermatological diseases. It affects more than 85% of teenagers, especially of the male gender. Despite being infrequent in adulthood, recent epidemiological data show a growing prevalence, around 40%, mainly in the female gender, with a negative impact on quality of life. Acne in adulthood or late acne is present after the age of 25 and is classified as late onset acne or persistent acne. The persistent type, which is the most common, represents 70% - 80% of all cases, and is characterised by the persistence of the teenage acne, while late onset acne is defined by the onset after the age of 25, with a prevalence of about 20% to 30%.Objective: To review current scientific literature, especially focused on the pathophysiology of late acne, triggering and aggravating factors, as well as particularities of the therapeutic approach.Methodology: The MEDLINE-PubMed database was used to select original and review articles published between 2001 and 2017.Discussion: Acne can be a clinical sign of systemic disease, mainly with endocrinological abnormalities, as polycystic ovary syndrome, adrenal hyperplasia and virilising tumours. It is important to consider these etiologies into account, especially in women and in the presence of other signs of hyperandrogenism. Several studies point to other triggering or aggravating factors, namely genetic factors, stress, smoking, exposure to ultraviolet radiation, obesity, hyperglycaemic diet, drugs, cosmetics and colonisation by resistant strains of Propionibacterium acnes.Conclusion: In most cases, adult acne affects the face, has mild to moderate clinical severity and is associated with normal hormonal levels. The exclusive location on the lower third of the face is most often associated with other signs of hyperandrogenism and endocrinological disease, as well as with a predominance of inflammatory lesions. Late acne is described as potentially refractory to the conventional therapy and is very relapsing. Thus, it is a therapeutic challenge, which requires an individualized approach. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-10-05T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.76.3.953 oai:ojs.revista.spdv.com.pt:article/953 |
url |
https://doi.org/10.29021/spdv.76.3.953 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/953 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/953 https://doi.org/10.29021/spdv.76.3.953 https://revista.spdv.com.pt/index.php/spdv/article/view/953/586 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 3 (2018): July - September; 299-312 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 3 (2018): Julho - Setembro; 299-312 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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repository.mail.fl_str_mv |
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1777301588876984320 |