Cardiac biomarkers in acute coronary syndromes
Main Author: | |
---|---|
Publication Date: | 2006 |
Other Authors: | , , |
Format: | Article |
Language: | por |
Source: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Download full: | https://revista.spmi.pt/index.php/rpmi/article/view/1635 |
Summary: | Proper evaluation of the patient with acute chest pain is a difficult challenge faced daily by Emergency Room physicians. Admitting patients with low probability of having an Acute Coronary Syndrome may become unaffordable both financially and logistically; on the other side of this delicate balance is the risk of misdiagnosis. Cardiac biomarkers are the third essential element in the diagnostic approach of Acute Coronary Syndromes, in addition to clinical symptoms and the results of the electrocardiogram. The clinical evaluation is often limited by atypical symptoms and not infrequently the initial electrocardiogram is nondiagnostic. In these patients with atypical presentations of Acute Coronary Syndromes the quantification of cardiac biomarkers is particularly important.The knowledge of the release kinetics of theses substances, the techniques used to quantify them, their reference values and their advantages and disadvantages is fundamental in order to use them adequately in a specific clinical context.In addition to their utility in the diagnosis or exclusion of acute myocardial infarction, cardiac biomarkers provide prognostic information (risk stratification) and are helpful in indicating therapeutic strategies for Acute Coronary Syndromes.This article reviews cardiac biomarkers now available in the hospital practice. |
id |
RCAP_5a4110cb97f70f9a4dd7cc163c6df4dd |
---|---|
oai_identifier_str |
oai:oai.revista.spmi.pt:article/1635 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Cardiac biomarkers in acute coronary syndromesBiomarcadores cardíacos nas síndromes coronárias agudasSíndromes coronárias agudasBiomarcadores cardíacosMarcadores de necrose miocárdicaTroponinaMioglobinaCreatina fosfoquinaseAcute Coronary Syndromescardiac biomarkersmarkers of myocardial necrosistroponinmyoglobincreatine kinaseProper evaluation of the patient with acute chest pain is a difficult challenge faced daily by Emergency Room physicians. Admitting patients with low probability of having an Acute Coronary Syndrome may become unaffordable both financially and logistically; on the other side of this delicate balance is the risk of misdiagnosis. Cardiac biomarkers are the third essential element in the diagnostic approach of Acute Coronary Syndromes, in addition to clinical symptoms and the results of the electrocardiogram. The clinical evaluation is often limited by atypical symptoms and not infrequently the initial electrocardiogram is nondiagnostic. In these patients with atypical presentations of Acute Coronary Syndromes the quantification of cardiac biomarkers is particularly important.The knowledge of the release kinetics of theses substances, the techniques used to quantify them, their reference values and their advantages and disadvantages is fundamental in order to use them adequately in a specific clinical context.In addition to their utility in the diagnosis or exclusion of acute myocardial infarction, cardiac biomarkers provide prognostic information (risk stratification) and are helpful in indicating therapeutic strategies for Acute Coronary Syndromes.This article reviews cardiac biomarkers now available in the hospital practice.A triagem de doentes com dor torácica é um desafi o difícil, lançado diariamente aos médicos em Serviço de Urgência. A admissão hospitalar de casos com baixa probabilidade de Síndrome Coronária Aguda pode tornar-se incomportável, financeira e logisticamente; do outro lado desta delicada balança está o risco de se dar alta a doentes com enfarte agudo do miocárdio. Os biomarcadores cardíacos são, para além da clínica e do electrocardiograma, o terceiro elemento fundamental para a abordagem diagnóstica das síndromes coronárias agudas. A avaliação clínica é frequentemente limitada por sintomas atípicos e, não raras vezes, o electrocardiograma inicial não permite o diagnóstico. É nestes doentes com um quadro clínico pouco claro que o doseamento dos biomarcadores cardíacos assume particular importância. O conhecimento do padrão de subida destas substâncias no sangue periférico, das técnicas usadas para a sua medição, dos valores de referência e das suas vantagens e desvantagens é fundamental para uma utilização adequada em determinado contexto clínico. Para além da sua utilidade no diagnóstico ou na exclusão de enfarte agudo do miocárdio, os biomarcadores cardíacos fornecem informação prognóstica (estratifi cação de risco) e são utilizados para orientação terapêutica.Neste artigo é feita uma revisão dos biomarcadores cardíacos actualmente disponíveis na prática clínica hospitalarSociedade Portuguesa de Medicina Interna2006-06-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spmi.pt/index.php/rpmi/article/view/1635Internal Medicine; Vol. 13 No. 2 (2006): Abril/ Junho; 113-125Medicina Interna; Vol. 13 N.º 2 (2006): Abril/ Junho; 113-1252183-99800872-671Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spmi.pt/index.php/rpmi/article/view/1635https://revista.spmi.pt/index.php/rpmi/article/view/1635/1102Henriques, SílviaLélis, ManuelaJesus, HerbertoNóbrega Araújo, Jorgeinfo:eu-repo/semantics/openAccess2023-02-25T06:11:07Zoai:oai.revista.spmi.pt:article/1635Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:47:17.035769Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Cardiac biomarkers in acute coronary syndromes Biomarcadores cardíacos nas síndromes coronárias agudas |
title |
Cardiac biomarkers in acute coronary syndromes |
spellingShingle |
Cardiac biomarkers in acute coronary syndromes Henriques, Sílvia Síndromes coronárias agudas Biomarcadores cardíacos Marcadores de necrose miocárdica Troponina Mioglobina Creatina fosfoquinase Acute Coronary Syndromes cardiac biomarkers markers of myocardial necrosis troponin myoglobin creatine kinase |
title_short |
Cardiac biomarkers in acute coronary syndromes |
title_full |
Cardiac biomarkers in acute coronary syndromes |
title_fullStr |
Cardiac biomarkers in acute coronary syndromes |
title_full_unstemmed |
Cardiac biomarkers in acute coronary syndromes |
title_sort |
Cardiac biomarkers in acute coronary syndromes |
author |
Henriques, Sílvia |
author_facet |
Henriques, Sílvia Lélis, Manuela Jesus, Herberto Nóbrega Araújo, Jorge |
author_role |
author |
author2 |
Lélis, Manuela Jesus, Herberto Nóbrega Araújo, Jorge |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Henriques, Sílvia Lélis, Manuela Jesus, Herberto Nóbrega Araújo, Jorge |
dc.subject.por.fl_str_mv |
Síndromes coronárias agudas Biomarcadores cardíacos Marcadores de necrose miocárdica Troponina Mioglobina Creatina fosfoquinase Acute Coronary Syndromes cardiac biomarkers markers of myocardial necrosis troponin myoglobin creatine kinase |
topic |
Síndromes coronárias agudas Biomarcadores cardíacos Marcadores de necrose miocárdica Troponina Mioglobina Creatina fosfoquinase Acute Coronary Syndromes cardiac biomarkers markers of myocardial necrosis troponin myoglobin creatine kinase |
description |
Proper evaluation of the patient with acute chest pain is a difficult challenge faced daily by Emergency Room physicians. Admitting patients with low probability of having an Acute Coronary Syndrome may become unaffordable both financially and logistically; on the other side of this delicate balance is the risk of misdiagnosis. Cardiac biomarkers are the third essential element in the diagnostic approach of Acute Coronary Syndromes, in addition to clinical symptoms and the results of the electrocardiogram. The clinical evaluation is often limited by atypical symptoms and not infrequently the initial electrocardiogram is nondiagnostic. In these patients with atypical presentations of Acute Coronary Syndromes the quantification of cardiac biomarkers is particularly important.The knowledge of the release kinetics of theses substances, the techniques used to quantify them, their reference values and their advantages and disadvantages is fundamental in order to use them adequately in a specific clinical context.In addition to their utility in the diagnosis or exclusion of acute myocardial infarction, cardiac biomarkers provide prognostic information (risk stratification) and are helpful in indicating therapeutic strategies for Acute Coronary Syndromes.This article reviews cardiac biomarkers now available in the hospital practice. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-06-30 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revista.spmi.pt/index.php/rpmi/article/view/1635 |
url |
https://revista.spmi.pt/index.php/rpmi/article/view/1635 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spmi.pt/index.php/rpmi/article/view/1635 https://revista.spmi.pt/index.php/rpmi/article/view/1635/1102 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Medicina Interna |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Medicina Interna |
dc.source.none.fl_str_mv |
Internal Medicine; Vol. 13 No. 2 (2006): Abril/ Junho; 113-125 Medicina Interna; Vol. 13 N.º 2 (2006): Abril/ Junho; 113-125 2183-9980 0872-671X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799130944295141376 |