Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island

Detalhes bibliográficos
Autor(a) principal: Mocan, Andrei
Data de Publicação: 2018
Outros Autores: Fernandes, Ângela, Calhelha, Ricardo C., Gavrilas, Laura, Ferreira, Isabel C.F.R., Ivanov, Marija, Barros, Lillian, Babotă, Mihai
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/24313
Resumo: The members of Cystus genus are perenial shrubs with a well-established use in traditional medicine. Among these, C. creticus is the most popular, herbal preparations obtained from its aerial parts being recognized as antimicrobial, antitumor and anti-inflammatory agents. The present study aimed to evaluate phytochemical profile and bioactive potential of aqueous and hydroethanolic extracts of C. creticus aerial parts harvested from two different areas of Rhodes island. LC-DAD-ESI/MSn analysis revealed the presence of myricetin and quercetin glycosides as main compounds, especially in aqueous extracts, being probably responsible for their enhanced antioxidant and antimicrobial potential. On the other side, hydroethanolic preparations exerted a strong anti-inflammatory and anti-biofilm activity. Our findings suggest that the use of solvents with intermediate polarity can assure the best recovery of bioactive compounds from C. creticus, increasing the extraction yield for other non-phenolic compounds which can enhance therapeutic potential of the extract through a synergistic action.
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spelling Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes IslandBioactive compoundsNatural antioxidanteAntimicrobial compoundsCystus creticusHerbal preparationsThe members of Cystus genus are perenial shrubs with a well-established use in traditional medicine. Among these, C. creticus is the most popular, herbal preparations obtained from its aerial parts being recognized as antimicrobial, antitumor and anti-inflammatory agents. The present study aimed to evaluate phytochemical profile and bioactive potential of aqueous and hydroethanolic extracts of C. creticus aerial parts harvested from two different areas of Rhodes island. LC-DAD-ESI/MSn analysis revealed the presence of myricetin and quercetin glycosides as main compounds, especially in aqueous extracts, being probably responsible for their enhanced antioxidant and antimicrobial potential. On the other side, hydroethanolic preparations exerted a strong anti-inflammatory and anti-biofilm activity. Our findings suggest that the use of solvents with intermediate polarity can assure the best recovery of bioactive compounds from C. creticus, increasing the extraction yield for other non-phenolic compounds which can enhance therapeutic potential of the extract through a synergistic action.This work was supported by a grant of the Romanian Ministry of Education and Research, CNCS–UEFISCDI, project number PN-III-P2-2.1-PED-2019-5360. This research was funded by the Serbian Ministry of Education, Science and Technological Development (Contract No. 451–03–9/2021–14/200007). The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2020); the national funding by FCT, P.I., through the institutional scientific employment program-contract for LB, RC, and ÂF contract.MDPIBiblioteca Digital do IPBMocan, AndreiFernandes, ÂngelaCalhelha, Ricardo C.Gavrilas, LauraFerreira, Isabel C.F.R.Ivanov, MarijaBarros, LillianBabotă, Mihai2018-01-19T10:00:00Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/24313engMocan, Andrei; Fernandes, Ângela; Calhelha, Ricardo C.; Gavrilas, Laura; Ferreira, Isabel C.F.R.; Sokovic, Marija Ivanov; Barros, Lillian; Babota, Mihai (2022). Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island. Frontiers in Nutrition. ISSN 2296-861X. 9, p. 1-92296-861X10.3389/fnut.2022.881210info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:54:22Zoai:bibliotecadigital.ipb.pt:10198/24313Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:15:09.697781Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
title Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
spellingShingle Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
Mocan, Andrei
Bioactive compounds
Natural antioxidante
Antimicrobial compounds
Cystus creticus
Herbal preparations
title_short Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
title_full Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
title_fullStr Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
title_full_unstemmed Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
title_sort Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island
author Mocan, Andrei
author_facet Mocan, Andrei
Fernandes, Ângela
Calhelha, Ricardo C.
Gavrilas, Laura
Ferreira, Isabel C.F.R.
Ivanov, Marija
Barros, Lillian
Babotă, Mihai
author_role author
author2 Fernandes, Ângela
Calhelha, Ricardo C.
Gavrilas, Laura
Ferreira, Isabel C.F.R.
Ivanov, Marija
Barros, Lillian
Babotă, Mihai
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Mocan, Andrei
Fernandes, Ângela
Calhelha, Ricardo C.
Gavrilas, Laura
Ferreira, Isabel C.F.R.
Ivanov, Marija
Barros, Lillian
Babotă, Mihai
dc.subject.por.fl_str_mv Bioactive compounds
Natural antioxidante
Antimicrobial compounds
Cystus creticus
Herbal preparations
topic Bioactive compounds
Natural antioxidante
Antimicrobial compounds
Cystus creticus
Herbal preparations
description The members of Cystus genus are perenial shrubs with a well-established use in traditional medicine. Among these, C. creticus is the most popular, herbal preparations obtained from its aerial parts being recognized as antimicrobial, antitumor and anti-inflammatory agents. The present study aimed to evaluate phytochemical profile and bioactive potential of aqueous and hydroethanolic extracts of C. creticus aerial parts harvested from two different areas of Rhodes island. LC-DAD-ESI/MSn analysis revealed the presence of myricetin and quercetin glycosides as main compounds, especially in aqueous extracts, being probably responsible for their enhanced antioxidant and antimicrobial potential. On the other side, hydroethanolic preparations exerted a strong anti-inflammatory and anti-biofilm activity. Our findings suggest that the use of solvents with intermediate polarity can assure the best recovery of bioactive compounds from C. creticus, increasing the extraction yield for other non-phenolic compounds which can enhance therapeutic potential of the extract through a synergistic action.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-19T10:00:00Z
2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/24313
url http://hdl.handle.net/10198/24313
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Mocan, Andrei; Fernandes, Ângela; Calhelha, Ricardo C.; Gavrilas, Laura; Ferreira, Isabel C.F.R.; Sokovic, Marija Ivanov; Barros, Lillian; Babota, Mihai (2022). Bioactive compounds and functional properties of herbal preparations of Cystus creticus L. collected from Rhodes Island. Frontiers in Nutrition. ISSN 2296-861X. 9, p. 1-9
2296-861X
10.3389/fnut.2022.881210
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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