SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/124957 |
Resumo: | The SARS-CoV-2 pandemic has placed great strain on the most developed of health care systems, especially in the context of critical care. Although co-infections with cytomegalovirus (CMV) are frequent in the critically ill due to underlying immune suppression of multiple causes, the impact on COVID-19 patients remains unclear. Furthermore, severe COVID-19 has recently been associated with significant immune suppression, and this may in turn impact CMV reactivation, possibly contributing to clinical course. Nevertheless, multiple confounding factors in these patients will certainly challenge upcoming research. The authors present a case series of five patients admitted to the intensive care unit (ICU) in the context of respiratory failure due to severe COVID-19. All patients evolved with CMV reactivation during ICU stay. |
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SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patientsCo-infectionsCOVID-19Critical careCytomegalovirusSARS-CoV-2Medicine(all)The SARS-CoV-2 pandemic has placed great strain on the most developed of health care systems, especially in the context of critical care. Although co-infections with cytomegalovirus (CMV) are frequent in the critically ill due to underlying immune suppression of multiple causes, the impact on COVID-19 patients remains unclear. Furthermore, severe COVID-19 has recently been associated with significant immune suppression, and this may in turn impact CMV reactivation, possibly contributing to clinical course. Nevertheless, multiple confounding factors in these patients will certainly challenge upcoming research. The authors present a case series of five patients admitted to the intensive care unit (ICU) in the context of respiratory failure due to severe COVID-19. All patients evolved with CMV reactivation during ICU stay.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNMoniz, PatríciaBrito, SérgioPovoa, Pedro2021-09-22T02:13:33Z2021-07-012021-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/124957eng2077-0383PURE: 33718326https://doi.org/10.3390/jcm10132792info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:06:08Zoai:run.unl.pt:10362/124957Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:45:36.602035Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients |
title |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients |
spellingShingle |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients Moniz, Patrícia Co-infections COVID-19 Critical care Cytomegalovirus SARS-CoV-2 Medicine(all) |
title_short |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients |
title_full |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients |
title_fullStr |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients |
title_full_unstemmed |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients |
title_sort |
SARS-CoV-2 and cytomegalovirus co-infections—a case series of critically ill patients |
author |
Moniz, Patrícia |
author_facet |
Moniz, Patrícia Brito, Sérgio Povoa, Pedro |
author_role |
author |
author2 |
Brito, Sérgio Povoa, Pedro |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Moniz, Patrícia Brito, Sérgio Povoa, Pedro |
dc.subject.por.fl_str_mv |
Co-infections COVID-19 Critical care Cytomegalovirus SARS-CoV-2 Medicine(all) |
topic |
Co-infections COVID-19 Critical care Cytomegalovirus SARS-CoV-2 Medicine(all) |
description |
The SARS-CoV-2 pandemic has placed great strain on the most developed of health care systems, especially in the context of critical care. Although co-infections with cytomegalovirus (CMV) are frequent in the critically ill due to underlying immune suppression of multiple causes, the impact on COVID-19 patients remains unclear. Furthermore, severe COVID-19 has recently been associated with significant immune suppression, and this may in turn impact CMV reactivation, possibly contributing to clinical course. Nevertheless, multiple confounding factors in these patients will certainly challenge upcoming research. The authors present a case series of five patients admitted to the intensive care unit (ICU) in the context of respiratory failure due to severe COVID-19. All patients evolved with CMV reactivation during ICU stay. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-22T02:13:33Z 2021-07-01 2021-07-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/124957 |
url |
http://hdl.handle.net/10362/124957 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2077-0383 PURE: 33718326 https://doi.org/10.3390/jcm10132792 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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