Suboptimal control of cardiovascular risk factors in myocardial infarction survivors

Detalhes bibliográficos
Autor(a) principal: Vasco Rafael Sousa Silva
Data de Publicação: 2020
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/128672
Resumo: Introduction and Objectives: As short-term mortality continues to decrease after myocardial infarction (MI), secondary prevention strategies attain increasing relevance in order to prevent recurrent events. This study aimed at evaluating cardiovascular risk factor (CVRF) control, namely dyslipidemia, hypertension and diabetes mellitus, among a contemporary cohort of MI survivors who completed an exercise-based cardiac rehabilitation (EBCR) program. Methods: Observational, retrospective cohort study including patients admitted to a tertiary center with an AMI between November 2012 and April 2017, who completed a phase II EBCR program after discharge. Achievement of LDL cholesterol, blood pressure and HbA1c guideline recommended targets was assessed. Lipid profile parameters were assessed and compared at three separate moments (hospitalization, beginning and end of the program). Results: A total of 379 patients were included. Mean age was 58.8 ± 10.6 years and 81% were male. Considering the ESC guidelines contemporary to the data collection, 61%, 87% and 71% achieved the recommended LDL cholesterol, blood pressure and HbA1c targets, respectively, at the end of the program. Combining all three risk factors, 42% achieved recommended targets. High-sensitivity C reactive protein decreased between the beginning and the end of the program [0.14 (0.08-0.29) mg/L to 0.12 (0.06-0.26) mg/L; p<0.001]. Conclusion: Despite contemporary management strategies, a substantial number of patients presented suboptimal control of CVRF. Considering dyslipidemia, hypertension and diabetes mellitus combined, less than half of individuals achieved the recommended targets. These findings highlight a pivotal unmet need which could be particularly relevant in improving cardiovascular outcomes by enhancing secondary prevention profiles.
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spelling Suboptimal control of cardiovascular risk factors in myocardial infarction survivorsMedicina clínicaClinical medicineIntroduction and Objectives: As short-term mortality continues to decrease after myocardial infarction (MI), secondary prevention strategies attain increasing relevance in order to prevent recurrent events. This study aimed at evaluating cardiovascular risk factor (CVRF) control, namely dyslipidemia, hypertension and diabetes mellitus, among a contemporary cohort of MI survivors who completed an exercise-based cardiac rehabilitation (EBCR) program. Methods: Observational, retrospective cohort study including patients admitted to a tertiary center with an AMI between November 2012 and April 2017, who completed a phase II EBCR program after discharge. Achievement of LDL cholesterol, blood pressure and HbA1c guideline recommended targets was assessed. Lipid profile parameters were assessed and compared at three separate moments (hospitalization, beginning and end of the program). Results: A total of 379 patients were included. Mean age was 58.8 ± 10.6 years and 81% were male. Considering the ESC guidelines contemporary to the data collection, 61%, 87% and 71% achieved the recommended LDL cholesterol, blood pressure and HbA1c targets, respectively, at the end of the program. Combining all three risk factors, 42% achieved recommended targets. High-sensitivity C reactive protein decreased between the beginning and the end of the program [0.14 (0.08-0.29) mg/L to 0.12 (0.06-0.26) mg/L; p<0.001]. Conclusion: Despite contemporary management strategies, a substantial number of patients presented suboptimal control of CVRF. Considering dyslipidemia, hypertension and diabetes mellitus combined, less than half of individuals achieved the recommended targets. These findings highlight a pivotal unmet need which could be particularly relevant in improving cardiovascular outcomes by enhancing secondary prevention profiles.2020-06-032020-06-03T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/10216/128672TID:202619265engVasco Rafael Sousa Silvainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T12:36:43Zoai:repositorio-aberto.up.pt:10216/128672Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:23:28.051994Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
title Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
spellingShingle Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
Vasco Rafael Sousa Silva
Medicina clínica
Clinical medicine
title_short Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
title_full Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
title_fullStr Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
title_full_unstemmed Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
title_sort Suboptimal control of cardiovascular risk factors in myocardial infarction survivors
author Vasco Rafael Sousa Silva
author_facet Vasco Rafael Sousa Silva
author_role author
dc.contributor.author.fl_str_mv Vasco Rafael Sousa Silva
dc.subject.por.fl_str_mv Medicina clínica
Clinical medicine
topic Medicina clínica
Clinical medicine
description Introduction and Objectives: As short-term mortality continues to decrease after myocardial infarction (MI), secondary prevention strategies attain increasing relevance in order to prevent recurrent events. This study aimed at evaluating cardiovascular risk factor (CVRF) control, namely dyslipidemia, hypertension and diabetes mellitus, among a contemporary cohort of MI survivors who completed an exercise-based cardiac rehabilitation (EBCR) program. Methods: Observational, retrospective cohort study including patients admitted to a tertiary center with an AMI between November 2012 and April 2017, who completed a phase II EBCR program after discharge. Achievement of LDL cholesterol, blood pressure and HbA1c guideline recommended targets was assessed. Lipid profile parameters were assessed and compared at three separate moments (hospitalization, beginning and end of the program). Results: A total of 379 patients were included. Mean age was 58.8 ± 10.6 years and 81% were male. Considering the ESC guidelines contemporary to the data collection, 61%, 87% and 71% achieved the recommended LDL cholesterol, blood pressure and HbA1c targets, respectively, at the end of the program. Combining all three risk factors, 42% achieved recommended targets. High-sensitivity C reactive protein decreased between the beginning and the end of the program [0.14 (0.08-0.29) mg/L to 0.12 (0.06-0.26) mg/L; p<0.001]. Conclusion: Despite contemporary management strategies, a substantial number of patients presented suboptimal control of CVRF. Considering dyslipidemia, hypertension and diabetes mellitus combined, less than half of individuals achieved the recommended targets. These findings highlight a pivotal unmet need which could be particularly relevant in improving cardiovascular outcomes by enhancing secondary prevention profiles.
publishDate 2020
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