Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.21/9386 |
Resumo: | Swine production workers are exposed simultaneously to multiple contaminants. Occupational exposure to aflatoxin B1 (AFB1) in Portuguese swine production farms has already been reported. However, besides AFB1, data regarding fungal contamination showed that exposure to other mycotoxins could be expected in this setting. The present study aimed to characterize the occupational exposure to multiple mycotoxins of swine production workers. To provide a broad view on the burden of contamination by mycotoxins and the workers’ exposure, biological (urine) samples from workers (n = 25) and 38 environmental samples (air samples, n = 23; litter samples, n = 5; feed samples, n = 10) were collected. The mycotoxins biomarkers detected in the urine samples of the workers' group were the deoxynivalenol-glucuronic acid conjugate (60%), aflatoxin M1 (16%), enniatin B (4%), citrinin (8%), dihydrocitrinone (12%) and ochratoxin A (80%). Results of the control group followed the same pattern, but in general with a lower number of quantifiable results (<LOQ). Besides air samples, all the other environmental samples collected presented high and diverse contamination, and deoxynivalenol (DON), like in the biomonitoring results, was the most prominent mycotoxin. The results demonstrate that the occupational environment is adding and contributing to the workers’ total exposure to mycotoxins, particularly in the case of DON. This was confirmed by the biomonitoring data and the high contamination found in feed and litter samples. Furthermore, he followed multi-biomarker approach allowed to conclude that workers and the general population are exposed to several mycotoxins simultaneously. Moreover, occupational exposure is probably described as being intermittent and with very high concentrations for short durations. This should be reflected in the risk assessment process. |
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Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approachesOccupational healthOccupational exposureMycotoxinsSwineryBiomonitoringMycotoxins mixtureSwine production workers are exposed simultaneously to multiple contaminants. Occupational exposure to aflatoxin B1 (AFB1) in Portuguese swine production farms has already been reported. However, besides AFB1, data regarding fungal contamination showed that exposure to other mycotoxins could be expected in this setting. The present study aimed to characterize the occupational exposure to multiple mycotoxins of swine production workers. To provide a broad view on the burden of contamination by mycotoxins and the workers’ exposure, biological (urine) samples from workers (n = 25) and 38 environmental samples (air samples, n = 23; litter samples, n = 5; feed samples, n = 10) were collected. The mycotoxins biomarkers detected in the urine samples of the workers' group were the deoxynivalenol-glucuronic acid conjugate (60%), aflatoxin M1 (16%), enniatin B (4%), citrinin (8%), dihydrocitrinone (12%) and ochratoxin A (80%). Results of the control group followed the same pattern, but in general with a lower number of quantifiable results (<LOQ). Besides air samples, all the other environmental samples collected presented high and diverse contamination, and deoxynivalenol (DON), like in the biomonitoring results, was the most prominent mycotoxin. The results demonstrate that the occupational environment is adding and contributing to the workers’ total exposure to mycotoxins, particularly in the case of DON. This was confirmed by the biomonitoring data and the high contamination found in feed and litter samples. Furthermore, he followed multi-biomarker approach allowed to conclude that workers and the general population are exposed to several mycotoxins simultaneously. Moreover, occupational exposure is probably described as being intermittent and with very high concentrations for short durations. This should be reflected in the risk assessment process.MDPIRCIPLViegas, SusanaAssunção, RicardoMartins, CarlaNunes, CarlaOsteresch, BerndTwarużek, MagdalenaKosicki, RobertGrajewski, JanRibeiro, EdnaViegas, Carla2019-02-01T11:22:11Z2019-022019-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/9386engViegas S, Assunção R, Martins C, Nunes C, Ribeiro E, Viegas C, et al. Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches. Toxins. 2019;11(2):78.10.3390/toxins11020078info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T09:58:00Zoai:repositorio.ipl.pt:10400.21/9386Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:17:58.119320Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches |
title |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches |
spellingShingle |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches Viegas, Susana Occupational health Occupational exposure Mycotoxins Swinery Biomonitoring Mycotoxins mixture |
title_short |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches |
title_full |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches |
title_fullStr |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches |
title_full_unstemmed |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches |
title_sort |
Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches |
author |
Viegas, Susana |
author_facet |
Viegas, Susana Assunção, Ricardo Martins, Carla Nunes, Carla Osteresch, Bernd Twarużek, Magdalena Kosicki, Robert Grajewski, Jan Ribeiro, Edna Viegas, Carla |
author_role |
author |
author2 |
Assunção, Ricardo Martins, Carla Nunes, Carla Osteresch, Bernd Twarużek, Magdalena Kosicki, Robert Grajewski, Jan Ribeiro, Edna Viegas, Carla |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
RCIPL |
dc.contributor.author.fl_str_mv |
Viegas, Susana Assunção, Ricardo Martins, Carla Nunes, Carla Osteresch, Bernd Twarużek, Magdalena Kosicki, Robert Grajewski, Jan Ribeiro, Edna Viegas, Carla |
dc.subject.por.fl_str_mv |
Occupational health Occupational exposure Mycotoxins Swinery Biomonitoring Mycotoxins mixture |
topic |
Occupational health Occupational exposure Mycotoxins Swinery Biomonitoring Mycotoxins mixture |
description |
Swine production workers are exposed simultaneously to multiple contaminants. Occupational exposure to aflatoxin B1 (AFB1) in Portuguese swine production farms has already been reported. However, besides AFB1, data regarding fungal contamination showed that exposure to other mycotoxins could be expected in this setting. The present study aimed to characterize the occupational exposure to multiple mycotoxins of swine production workers. To provide a broad view on the burden of contamination by mycotoxins and the workers’ exposure, biological (urine) samples from workers (n = 25) and 38 environmental samples (air samples, n = 23; litter samples, n = 5; feed samples, n = 10) were collected. The mycotoxins biomarkers detected in the urine samples of the workers' group were the deoxynivalenol-glucuronic acid conjugate (60%), aflatoxin M1 (16%), enniatin B (4%), citrinin (8%), dihydrocitrinone (12%) and ochratoxin A (80%). Results of the control group followed the same pattern, but in general with a lower number of quantifiable results (<LOQ). Besides air samples, all the other environmental samples collected presented high and diverse contamination, and deoxynivalenol (DON), like in the biomonitoring results, was the most prominent mycotoxin. The results demonstrate that the occupational environment is adding and contributing to the workers’ total exposure to mycotoxins, particularly in the case of DON. This was confirmed by the biomonitoring data and the high contamination found in feed and litter samples. Furthermore, he followed multi-biomarker approach allowed to conclude that workers and the general population are exposed to several mycotoxins simultaneously. Moreover, occupational exposure is probably described as being intermittent and with very high concentrations for short durations. This should be reflected in the risk assessment process. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-02-01T11:22:11Z 2019-02 2019-02-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.21/9386 |
url |
http://hdl.handle.net/10400.21/9386 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Viegas S, Assunção R, Martins C, Nunes C, Ribeiro E, Viegas C, et al. Occupational exposure to mycotoxins in swine production: environmental and biological monitoring approaches. Toxins. 2019;11(2):78. 10.3390/toxins11020078 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133442961571840 |