Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis

Detalhes bibliográficos
Autor(a) principal: Saraiva,Miguel Mascarenhas
Data de Publicação: 2021
Outros Autores: Ribeiro,Tiago Filipe, Macedo,Guilherme
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452021000500354
Resumo: Abstract: The authors present the case of a 62-year-old male presenting with a relapse of ulcerative colitis. He had unprotected anal intercourse with other men and his medical record was remarkable for HIV infection. He was admitted to the emergency department with bloody diarrhea, tenesmus, urgency, and recent weight loss. Laboratory workup revealed de novo mild anemia and mild elevation of inflammation parameters. Endoscopic evaluation displayed loss of normal vascular pattern, edema, erythema, exudation, and superficial ulceration in the distal rectum. Biopsies showed chronic proctitis with mild to moderate activity. The patient was treated with intravenous glucocorticoids, but symptoms persisted. Extensive microbial study allowed the identification of multiple infectious agents with potential for infectious proctitis: cytomegalovirus, Chlamydia trachomatis, and Blastocystis hominis. This case highlights the importance of careful microbial investigation, supporting a detailed clinical history, in patients presenting with symptoms of inflammatory bowel disease flare, particularly in risk groups such as that with sexual risk.
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spelling Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential DiagnosisBlastocystis hominisUlcerative colitisCytomegalovirusInfectious proctitisLymphogranuloma venereumAbstract: The authors present the case of a 62-year-old male presenting with a relapse of ulcerative colitis. He had unprotected anal intercourse with other men and his medical record was remarkable for HIV infection. He was admitted to the emergency department with bloody diarrhea, tenesmus, urgency, and recent weight loss. Laboratory workup revealed de novo mild anemia and mild elevation of inflammation parameters. Endoscopic evaluation displayed loss of normal vascular pattern, edema, erythema, exudation, and superficial ulceration in the distal rectum. Biopsies showed chronic proctitis with mild to moderate activity. The patient was treated with intravenous glucocorticoids, but symptoms persisted. Extensive microbial study allowed the identification of multiple infectious agents with potential for infectious proctitis: cytomegalovirus, Chlamydia trachomatis, and Blastocystis hominis. This case highlights the importance of careful microbial investigation, supporting a detailed clinical history, in patients presenting with symptoms of inflammatory bowel disease flare, particularly in risk groups such as that with sexual risk.Sociedade Portuguesa de Gastrenterologia2021-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452021000500354GE-Portuguese Journal of Gastroenterology v.28 n.5 2021reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452021000500354Saraiva,Miguel MascarenhasRibeiro,Tiago FilipeMacedo,Guilhermeinfo:eu-repo/semantics/openAccess2023-07-27T12:36:39ZPortal AgregadorONG
dc.title.none.fl_str_mv Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
title Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
spellingShingle Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
Saraiva,Miguel Mascarenhas
Blastocystis hominis
Ulcerative colitis
Cytomegalovirus
Infectious proctitis
Lymphogranuloma venereum
title_short Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
title_full Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
title_fullStr Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
title_full_unstemmed Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
title_sort Infectious Proctitis in Ulcerative Colitis: The Importance of an Accurate Differential Diagnosis
author Saraiva,Miguel Mascarenhas
author_facet Saraiva,Miguel Mascarenhas
Ribeiro,Tiago Filipe
Macedo,Guilherme
author_role author
author2 Ribeiro,Tiago Filipe
Macedo,Guilherme
author2_role author
author
dc.contributor.author.fl_str_mv Saraiva,Miguel Mascarenhas
Ribeiro,Tiago Filipe
Macedo,Guilherme
dc.subject.por.fl_str_mv Blastocystis hominis
Ulcerative colitis
Cytomegalovirus
Infectious proctitis
Lymphogranuloma venereum
topic Blastocystis hominis
Ulcerative colitis
Cytomegalovirus
Infectious proctitis
Lymphogranuloma venereum
description Abstract: The authors present the case of a 62-year-old male presenting with a relapse of ulcerative colitis. He had unprotected anal intercourse with other men and his medical record was remarkable for HIV infection. He was admitted to the emergency department with bloody diarrhea, tenesmus, urgency, and recent weight loss. Laboratory workup revealed de novo mild anemia and mild elevation of inflammation parameters. Endoscopic evaluation displayed loss of normal vascular pattern, edema, erythema, exudation, and superficial ulceration in the distal rectum. Biopsies showed chronic proctitis with mild to moderate activity. The patient was treated with intravenous glucocorticoids, but symptoms persisted. Extensive microbial study allowed the identification of multiple infectious agents with potential for infectious proctitis: cytomegalovirus, Chlamydia trachomatis, and Blastocystis hominis. This case highlights the importance of careful microbial investigation, supporting a detailed clinical history, in patients presenting with symptoms of inflammatory bowel disease flare, particularly in risk groups such as that with sexual risk.
publishDate 2021
dc.date.none.fl_str_mv 2021-10-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452021000500354
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452021000500354
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452021000500354
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
dc.source.none.fl_str_mv GE-Portuguese Journal of Gastroenterology v.28 n.5 2021
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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