Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment

Detalhes bibliográficos
Autor(a) principal: Branco Caetano, F
Data de Publicação: 2022
Outros Autores: Milheiro Silva, T, Gonçalves, C, Dias, AI, Brito, MJ
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/4510
Resumo: When therapy with hepatotoxic drugs is being considered, all other possible contributing agents of liver damage should be held to account. While not generally considered a risk factor, we present 2 cases in which ketogenic diet (KD) may have played a role in liver injury due to antituberculosis drugs. Ketogenic diet has been linked to liver injury, and while its pathophysiology remains obscure, carnitine depletion could play a role, as it is a mechanism of liver damage common to KD and antituberculosis drug regimens.
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spelling Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis TreatmentDiet, KetogenicTuberculosisChemical and Drug Induced Liver InjuryHDE INF PEDHDE NEU PEDHDE GAS PEDWhen therapy with hepatotoxic drugs is being considered, all other possible contributing agents of liver damage should be held to account. While not generally considered a risk factor, we present 2 cases in which ketogenic diet (KD) may have played a role in liver injury due to antituberculosis drugs. Ketogenic diet has been linked to liver injury, and while its pathophysiology remains obscure, carnitine depletion could play a role, as it is a mechanism of liver damage common to KD and antituberculosis drug regimens.Wolters KluwerRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEBranco Caetano, FMilheiro Silva, TGonçalves, CDias, AIBrito, MJ2023-05-16T08:04:37Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/4510engJPGN Rep . 2022 Jun 21;3(3):e21610.1097/PG9.0000000000000216info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-05-21T05:33:17Zoai:repositorio.chlc.min-saude.pt:10400.17/4510Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:54:16.999838Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
title Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
spellingShingle Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
Branco Caetano, F
Diet, Ketogenic
Tuberculosis
Chemical and Drug Induced Liver Injury
HDE INF PED
HDE NEU PED
HDE GAS PED
title_short Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
title_full Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
title_fullStr Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
title_full_unstemmed Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
title_sort Ketogenic Diet and Drug-Induced Hepatotoxicity During Tuberculosis Treatment
author Branco Caetano, F
author_facet Branco Caetano, F
Milheiro Silva, T
Gonçalves, C
Dias, AI
Brito, MJ
author_role author
author2 Milheiro Silva, T
Gonçalves, C
Dias, AI
Brito, MJ
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Branco Caetano, F
Milheiro Silva, T
Gonçalves, C
Dias, AI
Brito, MJ
dc.subject.por.fl_str_mv Diet, Ketogenic
Tuberculosis
Chemical and Drug Induced Liver Injury
HDE INF PED
HDE NEU PED
HDE GAS PED
topic Diet, Ketogenic
Tuberculosis
Chemical and Drug Induced Liver Injury
HDE INF PED
HDE NEU PED
HDE GAS PED
description When therapy with hepatotoxic drugs is being considered, all other possible contributing agents of liver damage should be held to account. While not generally considered a risk factor, we present 2 cases in which ketogenic diet (KD) may have played a role in liver injury due to antituberculosis drugs. Ketogenic diet has been linked to liver injury, and while its pathophysiology remains obscure, carnitine depletion could play a role, as it is a mechanism of liver damage common to KD and antituberculosis drug regimens.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-01-01T00:00:00Z
2023-05-16T08:04:37Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/4510
url http://hdl.handle.net/10400.17/4510
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv JPGN Rep . 2022 Jun 21;3(3):e216
10.1097/PG9.0000000000000216
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wolters Kluwer
publisher.none.fl_str_mv Wolters Kluwer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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