Advances in Spiro Compounds

Detalhes bibliográficos
Autor(a) principal: Burke, Anthony
Data de Publicação: 1980
Outros Autores: Somsák, Lazlo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10174/24683
Resumo: Spiro compounds (also named as spiranes following the suggestion of Adolf von Baeyer as early as 1900) are ubiquitous molecules, which contain a fused bicyclic system that share a single atom. A search for the key term “spiro” in the SciFinder database at the beginning of April 2017 resulted in more than 147,000 hits including 5000–6000 publications per annum after 2010. This enormous research activity encompasses a large number of fields in chemistry (especially organic and medicinal chemistry—with an emphasis on heterocyclic systems), but also includes pharmacology, crystallography, materials science, physics, biochemistry, molecular biology, engineering, energy and fuels, just to mention the most active areas. The immense interest in spirocycles, besides their unique features related to isolation from natural sources, synthesis and stereochemistry, is fuelled by an extremely wide range of useful properties, that comprise among others anti-cancer, antibacterial, antifungal, anti-diabetic, anti-HIV, cytotoxic, diuretic, spasmolytic, antiphlogistic, anti-hypertensive, anti-depressant, anxiolytic, anti-fouling, anti-feedant, herbicidal, plant growth regulatory effects; photochromism; and hole-transporting ability.
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spelling Advances in Spiro CompoundsEspiroSínteseSpiro compounds (also named as spiranes following the suggestion of Adolf von Baeyer as early as 1900) are ubiquitous molecules, which contain a fused bicyclic system that share a single atom. A search for the key term “spiro” in the SciFinder database at the beginning of April 2017 resulted in more than 147,000 hits including 5000–6000 publications per annum after 2010. This enormous research activity encompasses a large number of fields in chemistry (especially organic and medicinal chemistry—with an emphasis on heterocyclic systems), but also includes pharmacology, crystallography, materials science, physics, biochemistry, molecular biology, engineering, energy and fuels, just to mention the most active areas. The immense interest in spirocycles, besides their unique features related to isolation from natural sources, synthesis and stereochemistry, is fuelled by an extremely wide range of useful properties, that comprise among others anti-cancer, antibacterial, antifungal, anti-diabetic, anti-HIV, cytotoxic, diuretic, spasmolytic, antiphlogistic, anti-hypertensive, anti-depressant, anxiolytic, anti-fouling, anti-feedant, herbicidal, plant growth regulatory effects; photochromism; and hole-transporting ability.MDPI AG2019-02-15T12:05:41Z2019-02-151980-06-30T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/24683http://hdl.handle.net/10174/24683eng1420-3049https://www.mdpi.com/journal/molecules/special_issues/spiroajb@uevora.ptnd307Burke, AnthonySomsák, Lazloinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T19:17:56Zoai:dspace.uevora.pt:10174/24683Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:15:19.167021Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Advances in Spiro Compounds
title Advances in Spiro Compounds
spellingShingle Advances in Spiro Compounds
Burke, Anthony
Espiro
Síntese
title_short Advances in Spiro Compounds
title_full Advances in Spiro Compounds
title_fullStr Advances in Spiro Compounds
title_full_unstemmed Advances in Spiro Compounds
title_sort Advances in Spiro Compounds
author Burke, Anthony
author_facet Burke, Anthony
Somsák, Lazlo
author_role author
author2 Somsák, Lazlo
author2_role author
dc.contributor.author.fl_str_mv Burke, Anthony
Somsák, Lazlo
dc.subject.por.fl_str_mv Espiro
Síntese
topic Espiro
Síntese
description Spiro compounds (also named as spiranes following the suggestion of Adolf von Baeyer as early as 1900) are ubiquitous molecules, which contain a fused bicyclic system that share a single atom. A search for the key term “spiro” in the SciFinder database at the beginning of April 2017 resulted in more than 147,000 hits including 5000–6000 publications per annum after 2010. This enormous research activity encompasses a large number of fields in chemistry (especially organic and medicinal chemistry—with an emphasis on heterocyclic systems), but also includes pharmacology, crystallography, materials science, physics, biochemistry, molecular biology, engineering, energy and fuels, just to mention the most active areas. The immense interest in spirocycles, besides their unique features related to isolation from natural sources, synthesis and stereochemistry, is fuelled by an extremely wide range of useful properties, that comprise among others anti-cancer, antibacterial, antifungal, anti-diabetic, anti-HIV, cytotoxic, diuretic, spasmolytic, antiphlogistic, anti-hypertensive, anti-depressant, anxiolytic, anti-fouling, anti-feedant, herbicidal, plant growth regulatory effects; photochromism; and hole-transporting ability.
publishDate 1980
dc.date.none.fl_str_mv 1980-06-30T00:00:00Z
2019-02-15T12:05:41Z
2019-02-15
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10174/24683
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https://www.mdpi.com/journal/molecules/special_issues/spiro
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