Human serum alcaline phosphatase and ageing.
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2003 |
| Outros Autores: | , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221 |
Resumo: | In experimental ageing models an inverse relationship between age and alkaline phosphatase activity has been observed.To characterize serum levels of alkaline phosphatase activity in humans according to age and gender.Serum alkaline phosphatase was determined in a random sample of 203 community dwellers aged 40 or more years.In men (n=87) total serum alkaline phosphatase markedly increased from the 5th to the 6th decade and then stabilized. For women (n=116) there was a slight increase in total serum alkaline phosphatase from the 5th to the 6th decade, followed by a bend upward after 69 years of age. There was a significant positive correlation between total serum alkaline phosphatase and age for the whole population.Serum alkaline phosphatase activity appears as a biomarker of age in humans, similarly to what has been described for experimental animal models. |
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Human serum alcaline phosphatase and ageing.Fosfátase alcalina sérica humana e envelhecimento.In experimental ageing models an inverse relationship between age and alkaline phosphatase activity has been observed.To characterize serum levels of alkaline phosphatase activity in humans according to age and gender.Serum alkaline phosphatase was determined in a random sample of 203 community dwellers aged 40 or more years.In men (n=87) total serum alkaline phosphatase markedly increased from the 5th to the 6th decade and then stabilized. For women (n=116) there was a slight increase in total serum alkaline phosphatase from the 5th to the 6th decade, followed by a bend upward after 69 years of age. There was a significant positive correlation between total serum alkaline phosphatase and age for the whole population.Serum alkaline phosphatase activity appears as a biomarker of age in humans, similarly to what has been described for experimental animal models.In experimental ageing models an inverse relationship between age and alkaline phosphatase activity has been observed.To characterize serum levels of alkaline phosphatase activity in humans according to age and gender.Serum alkaline phosphatase was determined in a random sample of 203 community dwellers aged 40 or more years.In men (n=87) total serum alkaline phosphatase markedly increased from the 5th to the 6th decade and then stabilized. For women (n=116) there was a slight increase in total serum alkaline phosphatase from the 5th to the 6th decade, followed by a bend upward after 69 years of age. There was a significant positive correlation between total serum alkaline phosphatase and age for the whole population.Serum alkaline phosphatase activity appears as a biomarker of age in humans, similarly to what has been described for experimental animal models.Ordem dos Médicos2003-12-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221oai:ojs.www.actamedicaportuguesa.com:article/1221Acta Médica Portuguesa; Vol. 16 No. 6 (2003): November-December; 395-400Acta Médica Portuguesa; Vol. 16 N.º 6 (2003): Novembro-Dezembro; 395-4001646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221/873Negrão, M RMartins, M JRamos, EBarros, HHipólito-Reis, CAzevedo, Iinfo:eu-repo/semantics/openAccess2022-12-20T10:57:40Zoai:ojs.www.actamedicaportuguesa.com:article/1221Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:17:02.744095Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Human serum alcaline phosphatase and ageing. Fosfátase alcalina sérica humana e envelhecimento. |
| title |
Human serum alcaline phosphatase and ageing. |
| spellingShingle |
Human serum alcaline phosphatase and ageing. Negrão, M R |
| title_short |
Human serum alcaline phosphatase and ageing. |
| title_full |
Human serum alcaline phosphatase and ageing. |
| title_fullStr |
Human serum alcaline phosphatase and ageing. |
| title_full_unstemmed |
Human serum alcaline phosphatase and ageing. |
| title_sort |
Human serum alcaline phosphatase and ageing. |
| author |
Negrão, M R |
| author_facet |
Negrão, M R Martins, M J Ramos, E Barros, H Hipólito-Reis, C Azevedo, I |
| author_role |
author |
| author2 |
Martins, M J Ramos, E Barros, H Hipólito-Reis, C Azevedo, I |
| author2_role |
author author author author author |
| dc.contributor.author.fl_str_mv |
Negrão, M R Martins, M J Ramos, E Barros, H Hipólito-Reis, C Azevedo, I |
| description |
In experimental ageing models an inverse relationship between age and alkaline phosphatase activity has been observed.To characterize serum levels of alkaline phosphatase activity in humans according to age and gender.Serum alkaline phosphatase was determined in a random sample of 203 community dwellers aged 40 or more years.In men (n=87) total serum alkaline phosphatase markedly increased from the 5th to the 6th decade and then stabilized. For women (n=116) there was a slight increase in total serum alkaline phosphatase from the 5th to the 6th decade, followed by a bend upward after 69 years of age. There was a significant positive correlation between total serum alkaline phosphatase and age for the whole population.Serum alkaline phosphatase activity appears as a biomarker of age in humans, similarly to what has been described for experimental animal models. |
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2003 |
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2003-12-31 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221 oai:ojs.www.actamedicaportuguesa.com:article/1221 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221 |
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oai:ojs.www.actamedicaportuguesa.com:article/1221 |
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por |
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por |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1221/873 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Ordem dos Médicos |
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Ordem dos Médicos |
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Acta Médica Portuguesa; Vol. 16 No. 6 (2003): November-December; 395-400 Acta Médica Portuguesa; Vol. 16 N.º 6 (2003): Novembro-Dezembro; 395-400 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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