Primary Sjögren’s Syndrome – A theoretical revision

• Main Author: Coelho, Maria do Céu
• Publication Date: 2002
• Other Authors: Melo, Eduardo, Albuquerque, Ana, Saraiva, José Pedro, Pimentel, António
• Format: Article
• Language: por
• Source: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Download full: https://revista.spmi.pt/index.php/rpmi/article/view/1861
• topic: Sindroma de Sjögren; xerostomia; xeroftalmia; parotidite; nefrite; pneumonite; tiroide; arterite; Sjögren syndrome; xerostomia; xerophthalmia; parotitis; nephritis; pneumonitis; thyroiditis; arthritis

Sjögren’s Syndrome is a slowly progressive, inflammatory autoimmune disease,affecting primarily the exocrine glands. Although ocular and oral exocrine glands are affected most commonly, giving rise to sicca symptoms (xerophthalmia, xerostomia), the clinical picture can be that of multisystem complaints, with symptoms/ signs that can be subtle and insidious, and therefore unrecognised.Some authors consider it “the great mimicker”. It can mimic or coexist with many other autoimmune organ-specific, haematological, or neurological disorders.These are some of the reasons why despite its relatively high prevalence, SS is often underdiagnosed, and some call it an “orphan disease”.The authors review clinical, immunological, histophatological aspects and therapeuticoptions of the disease.