Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications

Detalhes bibliográficos
Autor(a) principal: Souza, Marthyna P.
Data de Publicação: 2014
Outros Autores: Vaz, Antônio Fernando, Correia, M. T. S., Cerqueira, M. A., Vicente, A. A., Cunha, Maria G. Carneiro da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/31588
Resumo: This study aimed at the encapsulation of quercetin into lecithin/chitosan nanoparticles using the electrostatic self-assembly technique, followed by evaluation of their functionality (antioxidant activity) and stability at different environmental conditions. These nanoparticles were characterized in terms of: average size, morphology, zeta potential, encapsulation efficiency, loading, and spectroscopic characteristics. Quercetin has been successfully encapsulated in lecithin/chitosan nanoparticles with an efficiency of 96.13 ± 0.44 %. Nanoparticles presented a spherical morphology with an average size of 168.58 ± 20.94 nm and a zeta potential of 56.46 ± 1.94 mV. Stability studies showed that nanoparticles are stable to temperatures ranging between 5 and 70 °C and a pH variation from 3.3 to 5.0. Moreover, encapsulated quercetin showed improved antioxidant properties when compared to free-quercetin. Our results suggest that quercetin-loaded lecithin/chitosan nanoparticles can be used in the manufacture of functional foods.
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spelling Quercetin-loaded lecithin/chitosan nanoparticles for functional food applicationsQuercetin-loaded nanoparticlesBioactive compounds encapsulationNanostructure self-assemblyLecithin/chitosan nanoparticlesAntioxidantScience & TechnologyThis study aimed at the encapsulation of quercetin into lecithin/chitosan nanoparticles using the electrostatic self-assembly technique, followed by evaluation of their functionality (antioxidant activity) and stability at different environmental conditions. These nanoparticles were characterized in terms of: average size, morphology, zeta potential, encapsulation efficiency, loading, and spectroscopic characteristics. Quercetin has been successfully encapsulated in lecithin/chitosan nanoparticles with an efficiency of 96.13 ± 0.44 %. Nanoparticles presented a spherical morphology with an average size of 168.58 ± 20.94 nm and a zeta potential of 56.46 ± 1.94 mV. Stability studies showed that nanoparticles are stable to temperatures ranging between 5 and 70 °C and a pH variation from 3.3 to 5.0. Moreover, encapsulated quercetin showed improved antioxidant properties when compared to free-quercetin. Our results suggest that quercetin-loaded lecithin/chitosan nanoparticles can be used in the manufacture of functional foods.Author Marthyna Pessoa de Souza thanks Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES/PDEE-Brazil) and Fundacao de Amparo a Ciencia e Tecnologia do Estado de Pernambuco (FACEPE, Brazil) for granting her scholarships. Miguel A. Cerqueira is recipient of a fellowship from the Fundacao para a Ciencia e Tecnologia (SFRH/BPD/72753/2010, FCT, POPH-QREN, and FSE Portugal). This research was financially supported by research grants and fellowships from the Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), as well as the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES) and Fundacao de Amparo a Ciencia e Tecnologia do Estado de Pernambuco (FACEPE).The support of EU Cost Actions FA0904 and FA1001 is gratefully acknowledged.SpringerUniversidade do MinhoSouza, Marthyna P.Vaz, Antônio FernandoCorreia, M. T. S.Cerqueira, M. A.Vicente, A. A.Cunha, Maria G. Carneiro da20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/31588engSouza, M. P.; Vaz, A. F. M.; Correia, M. T. S.; Cerqueira, M. A.; Vicente, A. A.; Carneiro-da-Cunha, M. G., Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications. Food and Bioprocess Technology, 7(4), 1088-1098, 20141935-51301935-514910.1007/s11947-013-1160-2info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:19:03Zoai:repositorium.sdum.uminho.pt:1822/31588Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:11:57.434920Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
title Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
spellingShingle Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
Souza, Marthyna P.
Quercetin-loaded nanoparticles
Bioactive compounds encapsulation
Nanostructure self-assembly
Lecithin/chitosan nanoparticles
Antioxidant
Science & Technology
title_short Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
title_full Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
title_fullStr Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
title_full_unstemmed Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
title_sort Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications
author Souza, Marthyna P.
author_facet Souza, Marthyna P.
Vaz, Antônio Fernando
Correia, M. T. S.
Cerqueira, M. A.
Vicente, A. A.
Cunha, Maria G. Carneiro da
author_role author
author2 Vaz, Antônio Fernando
Correia, M. T. S.
Cerqueira, M. A.
Vicente, A. A.
Cunha, Maria G. Carneiro da
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Souza, Marthyna P.
Vaz, Antônio Fernando
Correia, M. T. S.
Cerqueira, M. A.
Vicente, A. A.
Cunha, Maria G. Carneiro da
dc.subject.por.fl_str_mv Quercetin-loaded nanoparticles
Bioactive compounds encapsulation
Nanostructure self-assembly
Lecithin/chitosan nanoparticles
Antioxidant
Science & Technology
topic Quercetin-loaded nanoparticles
Bioactive compounds encapsulation
Nanostructure self-assembly
Lecithin/chitosan nanoparticles
Antioxidant
Science & Technology
description This study aimed at the encapsulation of quercetin into lecithin/chitosan nanoparticles using the electrostatic self-assembly technique, followed by evaluation of their functionality (antioxidant activity) and stability at different environmental conditions. These nanoparticles were characterized in terms of: average size, morphology, zeta potential, encapsulation efficiency, loading, and spectroscopic characteristics. Quercetin has been successfully encapsulated in lecithin/chitosan nanoparticles with an efficiency of 96.13 ± 0.44 %. Nanoparticles presented a spherical morphology with an average size of 168.58 ± 20.94 nm and a zeta potential of 56.46 ± 1.94 mV. Stability studies showed that nanoparticles are stable to temperatures ranging between 5 and 70 °C and a pH variation from 3.3 to 5.0. Moreover, encapsulated quercetin showed improved antioxidant properties when compared to free-quercetin. Our results suggest that quercetin-loaded lecithin/chitosan nanoparticles can be used in the manufacture of functional foods.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/31588
url http://hdl.handle.net/1822/31588
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Souza, M. P.; Vaz, A. F. M.; Correia, M. T. S.; Cerqueira, M. A.; Vicente, A. A.; Carneiro-da-Cunha, M. G., Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications. Food and Bioprocess Technology, 7(4), 1088-1098, 2014
1935-5130
1935-5149
10.1007/s11947-013-1160-2
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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