Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.21/16662 |
Resumo: | This project was partially supported by an IDI&CA grant [IPL/2020/OCLOVID-19_ESTeSL] by H&TRC- Health & Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa. |
| id |
RCAP_7d5ce86645869c12d9354e571ea63848 |
|---|---|
| oai_identifier_str |
oai:repositorio.ipl.pt:10400.21/16662 |
| network_acronym_str |
RCAP |
| network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| repository_id_str |
7160 |
| spelling |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroidOphthalmologyCOVID-19ChoroidGanglion cell layerOCTRetina thicknessRetinal nerve fiber layerIPL/2020/OCLOVID-19_ESTeSLThis project was partially supported by an IDI&CA grant [IPL/2020/OCLOVID-19_ESTeSL] by H&TRC- Health & Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa.Background: Neurotropic capabilities of SARS-COVs allow viruses to reach the central nervous system by hematogenous neuronal dissemination. The human retina, as an extension of the Central Nervous System, may have some neurodegenerative and/or vascular modifications related to COVID-19. Objectives: To evaluate choroidal and inner neural layers in participants previously recovered from COVID-19 compared to the control group using optical coherence tomography. Methods: With a cross-sectional approach, the sample (n = 96), consisting of patients who have recovered from COVID-19 (n = 56) and healthy participants control group (n = 40) were ophthalmologically characterized. The neurodegenerative and vascular histological assessment was performed using SD-OCT and the mean thickness was measured in Early Treatment Diabetic Retinopathy Study (ETDRS) subfields. The retinal nerve fiber layer, Ganglion cell layer, and subfoveal choroidal thickness were obtained through semi-automatic measurement. Results: A total of 40 controls (27 women [67.5%]) and 56 COVID-19 participants (34 women [60.8%]) were included in this first report. There were retinal thickness significant differences in nearly all inner ETDRS subfields: nasal 3 mm (p = .025), I3 (p = .049), and temporal 3 mm (p = .009). Also, a decrease in neural layers was found in the nasal 3 mm (p = .049) and temporal 3 mm (p = .029) during ganglion cell layer assessment. The peripapillary retinal nerve fiber layer thickness was thinner in the COVID-19 group in superior temporal (p = .019), nasal (p = .002), inferior temporal (p = .046), and global (p = .014). Concerning the subfoveal choroidal measurement, an increase was observed in the COVID-19 group (p = .002). Conclusion: Participants who had recovered from COVID-19 showed a non-glaucomatous neuropathy trend pattern. We found differences closer to the classic description of the “bow-tie” observed in other neurological as compressive neuropathies at the chiasma location. OCT assessment also showed an increase in choroidal thickness as a result of vascular changes.Taylor & FrancisRCIPLPoças, Ilda MariaLino, PedroSilva, CarinaMendonça, PaulaCunha, João PauloBarroqueiro, OlgaCarvalho, FranciscaNicho, InêsCastelhano, MarianaCondado, PatríciaCarmo, RitaAlmeida, JúlioPrieto, IsabelCamacho, Pedro2023-122023-12-01T00:00:00Z2025-12-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/16662engPoças IM, Lino P, Silva C, Mendonça P, Cunha JC, Camacho P, et al. Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid. Strabismus. 2023;31(4):271-80.10.1080/09273972.2023.2278639info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-27T02:15:40Zoai:repositorio.ipl.pt:10400.21/16662Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:42:27.387371Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid |
| title |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid |
| spellingShingle |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid Poças, Ilda Maria Ophthalmology COVID-19 Choroid Ganglion cell layer OCT Retina thickness Retinal nerve fiber layer IPL/2020/OCLOVID-19_ESTeSL |
| title_short |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid |
| title_full |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid |
| title_fullStr |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid |
| title_full_unstemmed |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid |
| title_sort |
Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid |
| author |
Poças, Ilda Maria |
| author_facet |
Poças, Ilda Maria Lino, Pedro Silva, Carina Mendonça, Paula Cunha, João Paulo Barroqueiro, Olga Carvalho, Francisca Nicho, Inês Castelhano, Mariana Condado, Patrícia Carmo, Rita Almeida, Júlio Prieto, Isabel Camacho, Pedro |
| author_role |
author |
| author2 |
Lino, Pedro Silva, Carina Mendonça, Paula Cunha, João Paulo Barroqueiro, Olga Carvalho, Francisca Nicho, Inês Castelhano, Mariana Condado, Patrícia Carmo, Rita Almeida, Júlio Prieto, Isabel Camacho, Pedro |
| author2_role |
author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
RCIPL |
| dc.contributor.author.fl_str_mv |
Poças, Ilda Maria Lino, Pedro Silva, Carina Mendonça, Paula Cunha, João Paulo Barroqueiro, Olga Carvalho, Francisca Nicho, Inês Castelhano, Mariana Condado, Patrícia Carmo, Rita Almeida, Júlio Prieto, Isabel Camacho, Pedro |
| dc.subject.por.fl_str_mv |
Ophthalmology COVID-19 Choroid Ganglion cell layer OCT Retina thickness Retinal nerve fiber layer IPL/2020/OCLOVID-19_ESTeSL |
| topic |
Ophthalmology COVID-19 Choroid Ganglion cell layer OCT Retina thickness Retinal nerve fiber layer IPL/2020/OCLOVID-19_ESTeSL |
| description |
This project was partially supported by an IDI&CA grant [IPL/2020/OCLOVID-19_ESTeSL] by H&TRC- Health & Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-12 2023-12-01T00:00:00Z 2025-12-10T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.21/16662 |
| url |
http://hdl.handle.net/10400.21/16662 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Poças IM, Lino P, Silva C, Mendonça P, Cunha JC, Camacho P, et al. Ocular repercussions in COVID-19 patients: structural changes of the retina and choroid. Strabismus. 2023;31(4):271-80. 10.1080/09273972.2023.2278639 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
| eu_rights_str_mv |
embargoedAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Taylor & Francis |
| publisher.none.fl_str_mv |
Taylor & Francis |
| dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
| instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| instacron_str |
RCAAP |
| institution |
RCAAP |
| reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
| repository.mail.fl_str_mv |
|
| _version_ |
1799136325676302336 |