Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement

Detalhes bibliográficos
Autor(a) principal: Oliveira, Teresa
Data de Publicação: 2019
Outros Autores: Lopes de Castro, José, Fragoso, João, Pereira, Alfredo, Manca, Antonio, Vitale-Broverone, Chiara, Queiroga, Cristina, Reis, Joana
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10174/25005
Resumo: Polymethylmethacrylate (PMMA) based cements are widely used for vertebroplasty. However, PMMA has disadvantages. The purpose of the present work was to test in vivo a new resorbable injectable composite cement – Spine-Ghost. The paste was percutaneously injected in bone defects manually drilled in L4 vertebral bodies of eight mature Merino sheep (Group B). A control group of eight sheep was injected with a known commercial calcium sulphate-based biphasic cement (Group A). After the 6-month implantation period the samples were assessed by micro-CT and histological studies. All sheep completed the 6-month implantation period. Cement resorption and new bone formation were observed in all samples with no signs of infection or inflammation.
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spelling Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cementresorbable cementpercutaneous vertebroplastysheepin vivoPolymethylmethacrylate (PMMA) based cements are widely used for vertebroplasty. However, PMMA has disadvantages. The purpose of the present work was to test in vivo a new resorbable injectable composite cement – Spine-Ghost. The paste was percutaneously injected in bone defects manually drilled in L4 vertebral bodies of eight mature Merino sheep (Group B). A control group of eight sheep was injected with a known commercial calcium sulphate-based biphasic cement (Group A). After the 6-month implantation period the samples were assessed by micro-CT and histological studies. All sheep completed the 6-month implantation period. Cement resorption and new bone formation were observed in all samples with no signs of infection or inflammation.UA Editora - Universidade de Aveiro2019-02-26T22:56:53Z2019-02-262019-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/25005http://hdl.handle.net/10174/25005porteresoliveira@gmail.comjcastro@uevora.ptjoaocfragoso@gmail.comapereira@uevora.ptndndndjmfcr@uevora.pt206isbn 978-972-789-586-1Oliveira, TeresaLopes de Castro, JoséFragoso, JoãoPereira, AlfredoManca, AntonioVitale-Broverone, ChiaraQueiroga, CristinaReis, Joanainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T19:18:45Zoai:dspace.uevora.pt:10174/25005Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:15:38.273612Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
title Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
spellingShingle Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
Oliveira, Teresa
resorbable cement
percutaneous vertebroplasty
sheep
in vivo
title_short Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
title_full Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
title_fullStr Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
title_full_unstemmed Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
title_sort Percutaneous vertebroplasty in sheep: testing a novel mesoporous bioactive glass/calcium sulphate cement
author Oliveira, Teresa
author_facet Oliveira, Teresa
Lopes de Castro, José
Fragoso, João
Pereira, Alfredo
Manca, Antonio
Vitale-Broverone, Chiara
Queiroga, Cristina
Reis, Joana
author_role author
author2 Lopes de Castro, José
Fragoso, João
Pereira, Alfredo
Manca, Antonio
Vitale-Broverone, Chiara
Queiroga, Cristina
Reis, Joana
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Teresa
Lopes de Castro, José
Fragoso, João
Pereira, Alfredo
Manca, Antonio
Vitale-Broverone, Chiara
Queiroga, Cristina
Reis, Joana
dc.subject.por.fl_str_mv resorbable cement
percutaneous vertebroplasty
sheep
in vivo
topic resorbable cement
percutaneous vertebroplasty
sheep
in vivo
description Polymethylmethacrylate (PMMA) based cements are widely used for vertebroplasty. However, PMMA has disadvantages. The purpose of the present work was to test in vivo a new resorbable injectable composite cement – Spine-Ghost. The paste was percutaneously injected in bone defects manually drilled in L4 vertebral bodies of eight mature Merino sheep (Group B). A control group of eight sheep was injected with a known commercial calcium sulphate-based biphasic cement (Group A). After the 6-month implantation period the samples were assessed by micro-CT and histological studies. All sheep completed the 6-month implantation period. Cement resorption and new bone formation were observed in all samples with no signs of infection or inflammation.
publishDate 2019
dc.date.none.fl_str_mv 2019-02-26T22:56:53Z
2019-02-26
2019-02-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10174/25005
http://hdl.handle.net/10174/25005
url http://hdl.handle.net/10174/25005
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv teresoliveira@gmail.com
jcastro@uevora.pt
joaocfragoso@gmail.com
apereira@uevora.pt
nd
nd
nd
jmfcr@uevora.pt
206
isbn 978-972-789-586-1
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv UA Editora - Universidade de Aveiro
publisher.none.fl_str_mv UA Editora - Universidade de Aveiro
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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