Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome

Detalhes bibliográficos
Autor(a) principal: Soares, Isabel
Data de Publicação: 2013
Outros Autores: Belsky, Jay, Mesquita, Ana Raquel Marcelino, Osório, Ana Alexandra Caldas, Sampaio, Adriana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/25331
Resumo: Uncorrected proof
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spelling Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndromeIndiscriminate behaviorInstitutionalized childrenWilliams syndromeSocial SciencesUncorrected proofWhy do some institutionalized children develop indiscriminate behavior (IB) while others do not? Consid- ering children with Williams syndrome (WS) may provide an answer because IB has been observed routinely among individuals with this rare genetic neurodevelopmental dis- order. By conceiving WS as a natural genetic model that mimics the indiscriminate phenotype and, more impor- tantly, is associated with the deletion of genes in a specific region, we propose an integrative conceptual framework that underscores the dynamic developmental interplay between genes, endophenotypes, and environment. In this article, we consider the etiology of IB among institutional- ized children, which emphasizes environmental factors, followed by the effect of such behavior on WS children’s hypersociability, which highlights the crosstalk between genes and neuropsychological features in programming their distinctive social-emotional/behavioral phenotype. We propose new hypotheses regarding the etiopathogenyof IBs in institutionalized children, particularly the pre- diction of specific gene-X-environment interactions.Fundação para a Ciência e a Tecnologia (FCT) - PTDC/PSI-PCL/116897/2010; PTDC/PSI PCL/115316/2009; PTDC/PSI-PCL/101506/2008WileyUniversidade do MinhoSoares, IsabelBelsky, JayMesquita, Ana Raquel MarcelinoOsório, Ana Alexandra CaldasSampaio, Adriana20132013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/25331eng1750-860610.1111/cdep.12036info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:50:50Zoai:repositorium.sdum.uminho.pt:1822/25331Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:49:35.940691Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
title Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
spellingShingle Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
Soares, Isabel
Indiscriminate behavior
Institutionalized children
Williams syndrome
Social Sciences
title_short Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
title_full Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
title_fullStr Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
title_full_unstemmed Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
title_sort Why do only some institutionalized children become indiscriminately friendly? Insights from the study of Williams syndrome
author Soares, Isabel
author_facet Soares, Isabel
Belsky, Jay
Mesquita, Ana Raquel Marcelino
Osório, Ana Alexandra Caldas
Sampaio, Adriana
author_role author
author2 Belsky, Jay
Mesquita, Ana Raquel Marcelino
Osório, Ana Alexandra Caldas
Sampaio, Adriana
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Soares, Isabel
Belsky, Jay
Mesquita, Ana Raquel Marcelino
Osório, Ana Alexandra Caldas
Sampaio, Adriana
dc.subject.por.fl_str_mv Indiscriminate behavior
Institutionalized children
Williams syndrome
Social Sciences
topic Indiscriminate behavior
Institutionalized children
Williams syndrome
Social Sciences
description Uncorrected proof
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/25331
url http://hdl.handle.net/1822/25331
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1750-8606
10.1111/cdep.12036
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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