Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.18/8920 |
Resumo: | Multicentre Study |
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Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021COVID-19SARS-CoV-2Delta VariantMulticentre StudyTest-negative DesignVaccine EffectivenessEuropeVacinaEfetividadeInfecções RespiratóriasCuidados de SaúdeEuropaI-MOVEMulticentre StudyI-MOVE-COVID-19 and ECDC primary care study team (in addition to authors above): Katica Čusek Adamić, Ivana Ferenčak, Bernard Kaić, Mirjana Lana Kosanović Ličina, Danijela Lakošeljac, Ivana Mihin Huskić, Diana Nonković, Nick Andrews, Jamie Lopez Bernal, Joanna Ellis, Heather Whitaker, Thierry Blanchon,, Caroline Guerrisi,, Titouan Launay,, Shirley Masse,, Sylvie van der Werf, Vincent Enouf, John Cuddihy, Lois O’Connor, Adele McKenna, Michael Joyce, Cillian de Gascun, Joanne Moran, Rianne van Gageldonk-Lafeber, Susan J Hahné, Hester E de Melker, Ewout B Fanoy, Stijn Raven, Marit Middeldorp, Irina Kislaya, Baltazar Nunes, Rita Roquete, Adriana Silva, Aryse Melo, Inês Costa, Nuno Verdasca, Patrícia Conde, Amélia Soeiro, Maria Elena Mihai, Iulia Bistriceanu, Alina Ivanciuc, Diana Dintoi, Catalina Pascu, Adrian Jidovu, Debbie Sigerson, Diogo FP Marques, Anna Molesworth, Leanne Quinn, Miranda Leyton, Selin Campbell, Janine Thoulass, Jim McMenamin, Inmaculada Casas Flecha, Ana Martínez Mateo, Daniel Castrillejo, Eva María Martínez Ochoa, Carmen Quiñones Rubio, Concepción Delgado-Sanz, Jesús Oliva, Ana Miqueleiz, Ana Navascués, Camino Trobajo-Sanmartín, Carmen Ezpeleta, Paula López Moreno, Javier Gorricho, Eva Ardanaz, Fernando Baigorria, Aurelio Barricarte, Cristina Burgui, Enrique de la Cruz, Nerea Egüés, Manuel García Cenoz, Marcela Guevara, Conchi Moreno-Iribas, Carmen Sayón, Pasi Penttinen, Christiana CarstairsIntroduction: In July and August 2021, the SARS-CoV-2 Delta variant dominated in Europe. Aim: Using a multicentre test-negative study, we measured COVID-19 vaccine effectiveness (VE) against symptomatic infection. Methods: Individuals with COVID-19 or acute respiratory symptoms at primary care/community level in 10 European countries were tested for SARS-CoV-2. We measured complete primary course overall VE by vaccine brand and by time since vaccination. Results: Overall VE was 74% (95% CI: 69–79), 76% (95% CI: 71–80), 63% (95% CI: 48–75) and 63% (95% CI: 16–83) among those aged 30–44, 45–59, 60–74 and ≥ 75 years, respectively. VE among those aged 30–59 years was 78% (95% CI: 75–81), 66% (95% CI: 58–73), 91% (95% CI: 87–94) and 52% (95% CI: 40–61), for Comirnaty, Vaxzevria, Spikevax and COVID-19 Vaccine Janssen, respectively. VE among people 60 years and older was 67% (95% CI: 52–77), 65% (95% CI: 48–76) and 83% (95% CI: 64–92) for Comirnaty, Vaxzevria and Spikevax, respectively. Comirnaty VE among those aged 30–59 years was 87% (95% CI: 83–89) at 14–29 days and 65% (95% CI: 56–71%) at ≥ 90 days between vaccination and onset of symptoms. Conclusions: VE against symptomatic infection with the SARS-CoV-2 Delta variant varied among brands, ranging from 52% to 91%. While some waning of the vaccine effect may be present (sample size limited this analysis to only Comirnaty), protection was 65% at 90 days or more between vaccination and onset.This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 101003673. This project received funding from the European Centre for Disease Prevention and Control (ECDC) under the contract ECD.11486.European Centre for Disease Prevention and ControlRepositório Científico do Instituto Nacional de SaúdeKissling, EstherHooiveld, MariëtteMartínez-Baz, IvánMazagatos, ClaraWilliam, NaomaVilcu, Ana-MariaKooijman, Marjolein N.Ilić, MajaDomegan, LisaMachado, Ausendade Lusignan, SimonLazar, MihaelaMeijer, AdamBrytting, MiaCasado, ItziarLarrauri, AmparoMurray, Josephine-L.K.Behillil, Sylviede Gier, BrechjeMlinarić, IvanO’Donnell, JoanRodrigues, Ana PaulaTsang, RubyTimnea, Oliviade Lange, MaritRiess, MaximilianCastilla, JesúsPozo, FranciscoHamilton, MarkFalchi, AlessandraKnol, Mirjam J.Kurečić Filipović, SanjaDunford, LindaGuiomar, RaquelCogdale, JadeCherciu, CarmenJansen, TessaEnkirch, TheresaBasile, LucaConnell, JeffGómez, VerónicaSandonis Martín, VirginiaBacci, SabrinaRose, Angela M.C.Pastore Celentano, LuciaValenciano, MartaI-MOVE-COVID-19 and ECDC primary care study teams2024-01-18T11:36:42Z2022-05-262022-05-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8920engEuro Surveill. 2022 May;27(21):2101104. doi: 10.2807/1560-7917.ES.2022.27.21.21011041560-791710.2807/1560-7917.ES.2022.27.21.2101104info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-20T01:31:52Zoai:repositorio.insa.pt:10400.18/8920Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:52:19.844753Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
| title |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
| spellingShingle |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 Kissling, Esther COVID-19 SARS-CoV-2 Delta Variant Multicentre Study Test-negative Design Vaccine Effectiveness Europe Vacina Efetividade Infecções Respiratórias Cuidados de Saúde Europa I-MOVE |
| title_short |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
| title_full |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
| title_fullStr |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
| title_full_unstemmed |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
| title_sort |
Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021 |
| author |
Kissling, Esther |
| author_facet |
Kissling, Esther Hooiveld, Mariëtte Martínez-Baz, Iván Mazagatos, Clara William, Naoma Vilcu, Ana-Maria Kooijman, Marjolein N. Ilić, Maja Domegan, Lisa Machado, Ausenda de Lusignan, Simon Lazar, Mihaela Meijer, Adam Brytting, Mia Casado, Itziar Larrauri, Amparo Murray, Josephine-L.K. Behillil, Sylvie de Gier, Brechje Mlinarić, Ivan O’Donnell, Joan Rodrigues, Ana Paula Tsang, Ruby Timnea, Olivia de Lange, Marit Riess, Maximilian Castilla, Jesús Pozo, Francisco Hamilton, Mark Falchi, Alessandra Knol, Mirjam J. Kurečić Filipović, Sanja Dunford, Linda Guiomar, Raquel Cogdale, Jade Cherciu, Carmen Jansen, Tessa Enkirch, Theresa Basile, Luca Connell, Jeff Gómez, Verónica Sandonis Martín, Virginia Bacci, Sabrina Rose, Angela M.C. Pastore Celentano, Lucia Valenciano, Marta I-MOVE-COVID-19 and ECDC primary care study teams |
| author_role |
author |
| author2 |
Hooiveld, Mariëtte Martínez-Baz, Iván Mazagatos, Clara William, Naoma Vilcu, Ana-Maria Kooijman, Marjolein N. Ilić, Maja Domegan, Lisa Machado, Ausenda de Lusignan, Simon Lazar, Mihaela Meijer, Adam Brytting, Mia Casado, Itziar Larrauri, Amparo Murray, Josephine-L.K. Behillil, Sylvie de Gier, Brechje Mlinarić, Ivan O’Donnell, Joan Rodrigues, Ana Paula Tsang, Ruby Timnea, Olivia de Lange, Marit Riess, Maximilian Castilla, Jesús Pozo, Francisco Hamilton, Mark Falchi, Alessandra Knol, Mirjam J. Kurečić Filipović, Sanja Dunford, Linda Guiomar, Raquel Cogdale, Jade Cherciu, Carmen Jansen, Tessa Enkirch, Theresa Basile, Luca Connell, Jeff Gómez, Verónica Sandonis Martín, Virginia Bacci, Sabrina Rose, Angela M.C. Pastore Celentano, Lucia Valenciano, Marta I-MOVE-COVID-19 and ECDC primary care study teams |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
| dc.contributor.author.fl_str_mv |
Kissling, Esther Hooiveld, Mariëtte Martínez-Baz, Iván Mazagatos, Clara William, Naoma Vilcu, Ana-Maria Kooijman, Marjolein N. Ilić, Maja Domegan, Lisa Machado, Ausenda de Lusignan, Simon Lazar, Mihaela Meijer, Adam Brytting, Mia Casado, Itziar Larrauri, Amparo Murray, Josephine-L.K. Behillil, Sylvie de Gier, Brechje Mlinarić, Ivan O’Donnell, Joan Rodrigues, Ana Paula Tsang, Ruby Timnea, Olivia de Lange, Marit Riess, Maximilian Castilla, Jesús Pozo, Francisco Hamilton, Mark Falchi, Alessandra Knol, Mirjam J. Kurečić Filipović, Sanja Dunford, Linda Guiomar, Raquel Cogdale, Jade Cherciu, Carmen Jansen, Tessa Enkirch, Theresa Basile, Luca Connell, Jeff Gómez, Verónica Sandonis Martín, Virginia Bacci, Sabrina Rose, Angela M.C. Pastore Celentano, Lucia Valenciano, Marta I-MOVE-COVID-19 and ECDC primary care study teams |
| dc.subject.por.fl_str_mv |
COVID-19 SARS-CoV-2 Delta Variant Multicentre Study Test-negative Design Vaccine Effectiveness Europe Vacina Efetividade Infecções Respiratórias Cuidados de Saúde Europa I-MOVE |
| topic |
COVID-19 SARS-CoV-2 Delta Variant Multicentre Study Test-negative Design Vaccine Effectiveness Europe Vacina Efetividade Infecções Respiratórias Cuidados de Saúde Europa I-MOVE |
| description |
Multicentre Study |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-05-26 2022-05-26T00:00:00Z 2024-01-18T11:36:42Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10400.18/8920 |
| url |
http://hdl.handle.net/10400.18/8920 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Euro Surveill. 2022 May;27(21):2101104. doi: 10.2807/1560-7917.ES.2022.27.21.2101104 1560-7917 10.2807/1560-7917.ES.2022.27.21.2101104 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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European Centre for Disease Prevention and Control |
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European Centre for Disease Prevention and Control |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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