Staphylococci phages display vast genomic diversity and evolutionary relationships

Detalhes bibliográficos
Autor(a) principal: Oliveira, Hugo
Data de Publicação: 2019
Outros Autores: Sampaio, Marta, Melo, Luís Daniel Rodrigues, Dias, Oscar, Pope, Welkin H., Hatfull, Graham F., Azeredo, Joana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/60431
Resumo: Bacteriophages are the most abundant and diverse entities in the biosphere, and this diversity is driven by constant predator--prey evolutionary dynamics and horizontal gene transfer. Phage genome sequences are under-sampled and therefore present an untapped and uncharacterized source of genetic diversity, typically characterized by highly mosaic genomes and no universal genes. To better understand the diversity and relationships among phages infecting human pathogens, we have analysed the complete genome sequences of 205 phages of Staphylococcus sp.
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spelling Staphylococci phages display vast genomic diversity and evolutionary relationshipsStaphylococcusBacteriophagesGenomesClustersPhamsEndolysinScience & TechnologyBacteriophages are the most abundant and diverse entities in the biosphere, and this diversity is driven by constant predator--prey evolutionary dynamics and horizontal gene transfer. Phage genome sequences are under-sampled and therefore present an untapped and uncharacterized source of genetic diversity, typically characterized by highly mosaic genomes and no universal genes. To better understand the diversity and relationships among phages infecting human pathogens, we have analysed the complete genome sequences of 205 phages of Staphylococcus sp.Financial support was provided by the Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/ 04469/2013 unit, COMPETE 2020 (POCI-01-0145-FEDER-006684) and FCT grant FRH/BPD/111653/2015 to HO. Funding was also provided by National Institutes of Health grant GM116884 and Howard Hughes Medical Institute grant 54308198 to GH. These funding bodies had no role in the design of the study, collection, analysis, and interpretation of data, or in writing the manuscript.info:eu-repo/semantics/publishedVersionSpringer NatureUniversidade do MinhoOliveira, HugoSampaio, MartaMelo, Luís Daniel RodriguesDias, OscarPope, Welkin H.Hatfull, Graham F.Azeredo, Joana2019-05-092019-05-09T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/60431engOliveira, Hugo; Sampaio, Marta; Melo, Luís D. R.; Dias, Oscar; Pope, Welkin H.; Hatfull, Graham F.; Azeredo, Joana, Staphylococci phages display vast genomic diversity and evolutionary relationships. BMC Genomics, 20(1), 357-357, 20191471-216410.1186/s12864-019-5647-831072320http://www.biomedcentral.com/bmcgenomicsinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:27:39Zoai:repositorium.sdum.uminho.pt:1822/60431Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:22:17.753736Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Staphylococci phages display vast genomic diversity and evolutionary relationships
title Staphylococci phages display vast genomic diversity and evolutionary relationships
spellingShingle Staphylococci phages display vast genomic diversity and evolutionary relationships
Oliveira, Hugo
Staphylococcus
Bacteriophages
Genomes
Clusters
Phams
Endolysin
Science & Technology
title_short Staphylococci phages display vast genomic diversity and evolutionary relationships
title_full Staphylococci phages display vast genomic diversity and evolutionary relationships
title_fullStr Staphylococci phages display vast genomic diversity and evolutionary relationships
title_full_unstemmed Staphylococci phages display vast genomic diversity and evolutionary relationships
title_sort Staphylococci phages display vast genomic diversity and evolutionary relationships
author Oliveira, Hugo
author_facet Oliveira, Hugo
Sampaio, Marta
Melo, Luís Daniel Rodrigues
Dias, Oscar
Pope, Welkin H.
Hatfull, Graham F.
Azeredo, Joana
author_role author
author2 Sampaio, Marta
Melo, Luís Daniel Rodrigues
Dias, Oscar
Pope, Welkin H.
Hatfull, Graham F.
Azeredo, Joana
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Oliveira, Hugo
Sampaio, Marta
Melo, Luís Daniel Rodrigues
Dias, Oscar
Pope, Welkin H.
Hatfull, Graham F.
Azeredo, Joana
dc.subject.por.fl_str_mv Staphylococcus
Bacteriophages
Genomes
Clusters
Phams
Endolysin
Science & Technology
topic Staphylococcus
Bacteriophages
Genomes
Clusters
Phams
Endolysin
Science & Technology
description Bacteriophages are the most abundant and diverse entities in the biosphere, and this diversity is driven by constant predator--prey evolutionary dynamics and horizontal gene transfer. Phage genome sequences are under-sampled and therefore present an untapped and uncharacterized source of genetic diversity, typically characterized by highly mosaic genomes and no universal genes. To better understand the diversity and relationships among phages infecting human pathogens, we have analysed the complete genome sequences of 205 phages of Staphylococcus sp.
publishDate 2019
dc.date.none.fl_str_mv 2019-05-09
2019-05-09T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/60431
url http://hdl.handle.net/1822/60431
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Oliveira, Hugo; Sampaio, Marta; Melo, Luís D. R.; Dias, Oscar; Pope, Welkin H.; Hatfull, Graham F.; Azeredo, Joana, Staphylococci phages display vast genomic diversity and evolutionary relationships. BMC Genomics, 20(1), 357-357, 2019
1471-2164
10.1186/s12864-019-5647-8
31072320
http://www.biomedcentral.com/bmcgenomics
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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