Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report

Detalhes bibliográficos
Autor(a) principal: Frutuoso,Beatriz
Data de Publicação: 2016
Outros Autores: Esteves,Joana, Silva,Mafalda, Gil,Pedro, Carneiro,Ana Cristina, Vale,Sílvio
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452016000300008
Resumo: Introduction: Intestinal angioedema is a rare adverse effect of angiotensin converting enzyme inhibitors. Clinical case: A 42-year old woman presented to the Emergency Department complaining of diffuse abdominal pain, predominantly in the right quadrants, with no other associated symptoms. She had been started on perindopril plus indapamide 72 h before the admission for arterial hypertension. There was no other relevant background. Physical examination suggested peritoneal irritation on the lower quadrants of the abdomen and right flank. Laboratory tests were relevant for mild leukocytosis. Abdomen ultrasound and contrast-enhanced computed tomography scan showed moderate amount of fluid in the pelvic excavation and small intestine wall thickening. She was admitted for observation. Once the hypothesis of intestinal angioedema was admitted, angiotensin converting enzyme inhibitor was withheld and no other-directed therapy was instituted. Within 24 h she showed clinical, analytic and imaging improvement, thus supporting this diagnosis. Conclusion: The diagnosis of intestinal angioedema induced by angiotensin converting enzyme inhibitor can be challenging and time consuming due to its rarity and nonspecific symptoms, which may lead to underdiagnosis of this entity.
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spelling Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case ReportAngioedemaAngiotensin-Converting Enzyme Inhibitors/adverse effectsIntestinal DiseasesIntroduction: Intestinal angioedema is a rare adverse effect of angiotensin converting enzyme inhibitors. Clinical case: A 42-year old woman presented to the Emergency Department complaining of diffuse abdominal pain, predominantly in the right quadrants, with no other associated symptoms. She had been started on perindopril plus indapamide 72 h before the admission for arterial hypertension. There was no other relevant background. Physical examination suggested peritoneal irritation on the lower quadrants of the abdomen and right flank. Laboratory tests were relevant for mild leukocytosis. Abdomen ultrasound and contrast-enhanced computed tomography scan showed moderate amount of fluid in the pelvic excavation and small intestine wall thickening. She was admitted for observation. Once the hypothesis of intestinal angioedema was admitted, angiotensin converting enzyme inhibitor was withheld and no other-directed therapy was instituted. Within 24 h she showed clinical, analytic and imaging improvement, thus supporting this diagnosis. Conclusion: The diagnosis of intestinal angioedema induced by angiotensin converting enzyme inhibitor can be challenging and time consuming due to its rarity and nonspecific symptoms, which may lead to underdiagnosis of this entity.Sociedade Portuguesa de Gastrenterologia2016-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452016000300008GE-Portuguese Journal of Gastroenterology v.23 n.3 2016reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452016000300008Frutuoso,BeatrizEsteves,JoanaSilva,MafaldaGil,PedroCarneiro,Ana CristinaVale,Sílvioinfo:eu-repo/semantics/openAccess2024-02-06T17:33:41Zoai:scielo:S2341-45452016000300008Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:35:57.270148Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
title Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
spellingShingle Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
Frutuoso,Beatriz
Angioedema
Angiotensin-Converting Enzyme Inhibitors/adverse effects
Intestinal Diseases
title_short Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
title_full Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
title_fullStr Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
title_full_unstemmed Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
title_sort Visceral Angioedema Induced by Angiotensin Converting Enzyme Inhibitor: Case Report
author Frutuoso,Beatriz
author_facet Frutuoso,Beatriz
Esteves,Joana
Silva,Mafalda
Gil,Pedro
Carneiro,Ana Cristina
Vale,Sílvio
author_role author
author2 Esteves,Joana
Silva,Mafalda
Gil,Pedro
Carneiro,Ana Cristina
Vale,Sílvio
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Frutuoso,Beatriz
Esteves,Joana
Silva,Mafalda
Gil,Pedro
Carneiro,Ana Cristina
Vale,Sílvio
dc.subject.por.fl_str_mv Angioedema
Angiotensin-Converting Enzyme Inhibitors/adverse effects
Intestinal Diseases
topic Angioedema
Angiotensin-Converting Enzyme Inhibitors/adverse effects
Intestinal Diseases
description Introduction: Intestinal angioedema is a rare adverse effect of angiotensin converting enzyme inhibitors. Clinical case: A 42-year old woman presented to the Emergency Department complaining of diffuse abdominal pain, predominantly in the right quadrants, with no other associated symptoms. She had been started on perindopril plus indapamide 72 h before the admission for arterial hypertension. There was no other relevant background. Physical examination suggested peritoneal irritation on the lower quadrants of the abdomen and right flank. Laboratory tests were relevant for mild leukocytosis. Abdomen ultrasound and contrast-enhanced computed tomography scan showed moderate amount of fluid in the pelvic excavation and small intestine wall thickening. She was admitted for observation. Once the hypothesis of intestinal angioedema was admitted, angiotensin converting enzyme inhibitor was withheld and no other-directed therapy was instituted. Within 24 h she showed clinical, analytic and imaging improvement, thus supporting this diagnosis. Conclusion: The diagnosis of intestinal angioedema induced by angiotensin converting enzyme inhibitor can be challenging and time consuming due to its rarity and nonspecific symptoms, which may lead to underdiagnosis of this entity.
publishDate 2016
dc.date.none.fl_str_mv 2016-06-01
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dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452016000300008
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dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
dc.source.none.fl_str_mv GE-Portuguese Journal of Gastroenterology v.23 n.3 2016
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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