Ganglioglioma of the neurohypophysis

Detalhes bibliográficos
Autor(a) principal: Scheithauer, BW
Data de Publicação: 2008
Outros Autores: Silva, AI, Parisi, JE, Kovacs, K, Horvath, E
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.23/568
Resumo: The normal infundibulum and neurohypophysis consist entirely of neuronal processes, the neuronal cell bodies of which lie within the supraoptic and paraventricular nuclei of the hypothalamus and supportive glial cells or pituicytes. The finding of neurons within the neurohypophysis is exceedingly rare, as are ganglion cell tumors at this site. In this paper, we report a ganglion cell tumor of the neurohypophysis found incidentally at autopsy. Despite chronic hypertension and the finding of some vasopressin immunoreactivity in lesional neurons, the syndrome of inappropriate antidiuretic hormone secretion (SIADH) was excluded on the basis of normal serum sodium levels. The morphologic and immunohistochemical features of the tumor are presented, cytogenetic considerations are discussed, and literature regarding neuronal lesions of the pituitary gland is reviewed
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spelling Ganglioglioma of the neurohypophysisGangliogliomaNeuro-HipófiseNeoplasias HipofisáriasThe normal infundibulum and neurohypophysis consist entirely of neuronal processes, the neuronal cell bodies of which lie within the supraoptic and paraventricular nuclei of the hypothalamus and supportive glial cells or pituicytes. The finding of neurons within the neurohypophysis is exceedingly rare, as are ganglion cell tumors at this site. In this paper, we report a ganglion cell tumor of the neurohypophysis found incidentally at autopsy. Despite chronic hypertension and the finding of some vasopressin immunoreactivity in lesional neurons, the syndrome of inappropriate antidiuretic hormone secretion (SIADH) was excluded on the basis of normal serum sodium levels. The morphologic and immunohistochemical features of the tumor are presented, cytogenetic considerations are discussed, and literature regarding neuronal lesions of the pituitary gland is reviewedSpringerRepositório Científico do Hospital de BragaScheithauer, BWSilva, AIParisi, JEKovacs, KHorvath, E2013-12-13T17:04:33Z2008-01-01T00:00:00Z2008-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.23/568engEndocr Pathol. 2008;19(2):112-6.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T09:02:15ZPortal AgregadorONG
dc.title.none.fl_str_mv Ganglioglioma of the neurohypophysis
title Ganglioglioma of the neurohypophysis
spellingShingle Ganglioglioma of the neurohypophysis
Scheithauer, BW
Ganglioglioma
Neuro-Hipófise
Neoplasias Hipofisárias
title_short Ganglioglioma of the neurohypophysis
title_full Ganglioglioma of the neurohypophysis
title_fullStr Ganglioglioma of the neurohypophysis
title_full_unstemmed Ganglioglioma of the neurohypophysis
title_sort Ganglioglioma of the neurohypophysis
author Scheithauer, BW
author_facet Scheithauer, BW
Silva, AI
Parisi, JE
Kovacs, K
Horvath, E
author_role author
author2 Silva, AI
Parisi, JE
Kovacs, K
Horvath, E
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Hospital de Braga
dc.contributor.author.fl_str_mv Scheithauer, BW
Silva, AI
Parisi, JE
Kovacs, K
Horvath, E
dc.subject.por.fl_str_mv Ganglioglioma
Neuro-Hipófise
Neoplasias Hipofisárias
topic Ganglioglioma
Neuro-Hipófise
Neoplasias Hipofisárias
description The normal infundibulum and neurohypophysis consist entirely of neuronal processes, the neuronal cell bodies of which lie within the supraoptic and paraventricular nuclei of the hypothalamus and supportive glial cells or pituicytes. The finding of neurons within the neurohypophysis is exceedingly rare, as are ganglion cell tumors at this site. In this paper, we report a ganglion cell tumor of the neurohypophysis found incidentally at autopsy. Despite chronic hypertension and the finding of some vasopressin immunoreactivity in lesional neurons, the syndrome of inappropriate antidiuretic hormone secretion (SIADH) was excluded on the basis of normal serum sodium levels. The morphologic and immunohistochemical features of the tumor are presented, cytogenetic considerations are discussed, and literature regarding neuronal lesions of the pituitary gland is reviewed
publishDate 2008
dc.date.none.fl_str_mv 2008-01-01T00:00:00Z
2008-01-01T00:00:00Z
2013-12-13T17:04:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.23/568
url http://hdl.handle.net/10400.23/568
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Endocr Pathol. 2008;19(2):112-6.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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