Materials incompatibility as a major cause of hip prostheses rejection

Detalhes bibliográficos
Autor(a) principal: Carvalho, Isabel
Data de Publicação: 2015
Outros Autores: Polcar, Tomas, Henriques, Mariana, Carvalho, S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/36424
Resumo: The development of new multifunctional coatings to apply on medical biomaterials continues to be required, since materials commonly used in hip prostheses still presenting failures. Multifunctionality is the result of a synergy, on the nanoscale level, of good corrosion, mechanical and tribological properties. Additionally, a biomaterial must always be biocompatible. Besides these properties, the major challenge would be to get a material that also has antimicrobial activity. In this context, the development of advanced materials with the ability to present these properties is being regarded as a strategy to prevent the colonization of implant and biofilm formation by bacteria. So, in this review, the attention is focused on the description of the funda- mental points of the natural synovial joint, since, its mechanical and tribological characteristics are the main causes that lead to the necessity of its replacement by an implant. Moreover, a contextualization was also performed on the hip replacement surgery and the biomaterials used, with a focus on their mechanical and tribological properties. Finally, it is explained the need of surface modification and the potential of TiCN coatings doped with silver.
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spelling Materials incompatibility as a major cause of hip prostheses rejectionScience & TechnologyThe development of new multifunctional coatings to apply on medical biomaterials continues to be required, since materials commonly used in hip prostheses still presenting failures. Multifunctionality is the result of a synergy, on the nanoscale level, of good corrosion, mechanical and tribological properties. Additionally, a biomaterial must always be biocompatible. Besides these properties, the major challenge would be to get a material that also has antimicrobial activity. In this context, the development of advanced materials with the ability to present these properties is being regarded as a strategy to prevent the colonization of implant and biofilm formation by bacteria. So, in this review, the attention is focused on the description of the funda- mental points of the natural synovial joint, since, its mechanical and tribological characteristics are the main causes that lead to the necessity of its replacement by an implant. Moreover, a contextualization was also performed on the hip replacement surgery and the biomaterials used, with a focus on their mechanical and tribological properties. Finally, it is explained the need of surface modification and the potential of TiCN coatings doped with silver.This research is sponsored by FEDER funds through the program COMPETE - Programa Operacional Factores de Competitividade - and by national funds through FCT - Fundacao para a Ciencia e a Tecnologia - in the framework of the Strategic Projects PEST-C/FIS/UI607/2011, PEST-C/EME/UI0285/2011, PTDC/CTM/102853/2008, and FCT - Fundacao para a Ciencia e a Tecnologia through the grant SFRH / BD / 67022 / 2009.The authors thank the FCT Strategic Project of UID/BIO/04469/2013 unit, the project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and the project "BioInd - Biotechnology and Bioengineering for improved Industrial and Agro-Food processes", REF. NORTE-07-0124-FEDER-000028 Co-funded by the Programa Operacional Regional do Norte (ON.2 - O Novo Norte), QREN, FEDER.Russian Academy of SciencesUniversidade do MinhoCarvalho, IsabelPolcar, TomasHenriques, MarianaCarvalho, S.2015-07-222015-07-22T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/36424engCarvalho, I.; Polcar, T; Henriques, Mariana; Carvalho, S., Materials incompatibility as a major cause of hip prostheses rejection. Reviews on Advanced Materials Science, 42(1), 36-49, 20151605-8127info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:46:39Zoai:repositorium.sdum.uminho.pt:1822/36424Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:44:39.733594Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Materials incompatibility as a major cause of hip prostheses rejection
title Materials incompatibility as a major cause of hip prostheses rejection
spellingShingle Materials incompatibility as a major cause of hip prostheses rejection
Carvalho, Isabel
Science & Technology
title_short Materials incompatibility as a major cause of hip prostheses rejection
title_full Materials incompatibility as a major cause of hip prostheses rejection
title_fullStr Materials incompatibility as a major cause of hip prostheses rejection
title_full_unstemmed Materials incompatibility as a major cause of hip prostheses rejection
title_sort Materials incompatibility as a major cause of hip prostheses rejection
author Carvalho, Isabel
author_facet Carvalho, Isabel
Polcar, Tomas
Henriques, Mariana
Carvalho, S.
author_role author
author2 Polcar, Tomas
Henriques, Mariana
Carvalho, S.
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Carvalho, Isabel
Polcar, Tomas
Henriques, Mariana
Carvalho, S.
dc.subject.por.fl_str_mv Science & Technology
topic Science & Technology
description The development of new multifunctional coatings to apply on medical biomaterials continues to be required, since materials commonly used in hip prostheses still presenting failures. Multifunctionality is the result of a synergy, on the nanoscale level, of good corrosion, mechanical and tribological properties. Additionally, a biomaterial must always be biocompatible. Besides these properties, the major challenge would be to get a material that also has antimicrobial activity. In this context, the development of advanced materials with the ability to present these properties is being regarded as a strategy to prevent the colonization of implant and biofilm formation by bacteria. So, in this review, the attention is focused on the description of the funda- mental points of the natural synovial joint, since, its mechanical and tribological characteristics are the main causes that lead to the necessity of its replacement by an implant. Moreover, a contextualization was also performed on the hip replacement surgery and the biomaterials used, with a focus on their mechanical and tribological properties. Finally, it is explained the need of surface modification and the potential of TiCN coatings doped with silver.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-22
2015-07-22T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/36424
url http://hdl.handle.net/1822/36424
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Carvalho, I.; Polcar, T; Henriques, Mariana; Carvalho, S., Materials incompatibility as a major cause of hip prostheses rejection. Reviews on Advanced Materials Science, 42(1), 36-49, 2015
1605-8127
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Russian Academy of Sciences
publisher.none.fl_str_mv Russian Academy of Sciences
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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