COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children

Detalhes bibliográficos
Autor(a) principal: Santos, Joana
Data de Publicação: 2022
Outros Autores: Botelho, Teresa, Caetano, Joana Serra, Cardoso, Rita, Dinis, Isabel, Mirante, Alice
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25754/pjp.2022.25777
Resumo: Introduction: Coronavirus disease 2019 pandemic has led to the adoption of extreme public health measures worldwide, and many governments imposed lockdown policies during the pandemic. In Portugal, the first emergency state began in March 2020 which led to the closure of schools and gyms, depriving children of all physical activities. This study aimed to evaluate the lockdown impact on metabolic control of children with type 1 diabetes. Methods: Children with type 1 diabetes, followed in the pediatric endocrinology unit of a tertiary care hospital were included in this study. Data were collected from 16/03/2019 to 15/12/2020 and analyzed by quarters: -Q4, -Q3, -Q2, -Q1, from 16/03/2019 to 15/03/2020, and Q1, Q2, and Q3 from 16/03/2020 to 15/12/2020. Metabolic control was evaluated by evolution of glycated hemoglobin, z-score of body mass index, and the insulin daily dose. The statistical analysis was performed using SPSS Statistics (version 23), and mean differences were considered statistically significant at p < 0.05. Results: This study included a total of 203 patients with a mean age of 10.8 ± 3.2 years and a type 1 diabetes duration of 6.4 ± 3.6 years. Moreover, 57.1% of the patients were male, and 86.7% were undergoing continuous subcutaneous insulin infusion. Mean glycated hemoglobin decreased from Q1 to Q2 (7.97% to 7.51%, p < 0.001) in all age groups, regardless of gender and type of treatment; however, it maintained the same value for the homologous periods -Q3 to Q2. Body mass index z-score increased from -Q4/-Q3 to Q2/Q3 (0.58 standard deviation to 0.71 standard deviation, p = 0.009). Insulin daily dose increased from -Q3 to Q3 (0.87 U/kg/day to 0.91 U/kg/day, p = 0.009). Conclusion: During the lockdown period, there was no worsening of metabolic control and parents made accurate adjustments to insulin doses, indicating a good level of knowledge regarding the treatment of type 1 diabetes.
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spelling COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in ChildrenOriginal articlesIntroduction: Coronavirus disease 2019 pandemic has led to the adoption of extreme public health measures worldwide, and many governments imposed lockdown policies during the pandemic. In Portugal, the first emergency state began in March 2020 which led to the closure of schools and gyms, depriving children of all physical activities. This study aimed to evaluate the lockdown impact on metabolic control of children with type 1 diabetes. Methods: Children with type 1 diabetes, followed in the pediatric endocrinology unit of a tertiary care hospital were included in this study. Data were collected from 16/03/2019 to 15/12/2020 and analyzed by quarters: -Q4, -Q3, -Q2, -Q1, from 16/03/2019 to 15/03/2020, and Q1, Q2, and Q3 from 16/03/2020 to 15/12/2020. Metabolic control was evaluated by evolution of glycated hemoglobin, z-score of body mass index, and the insulin daily dose. The statistical analysis was performed using SPSS Statistics (version 23), and mean differences were considered statistically significant at p < 0.05. Results: This study included a total of 203 patients with a mean age of 10.8 ± 3.2 years and a type 1 diabetes duration of 6.4 ± 3.6 years. Moreover, 57.1% of the patients were male, and 86.7% were undergoing continuous subcutaneous insulin infusion. Mean glycated hemoglobin decreased from Q1 to Q2 (7.97% to 7.51%, p < 0.001) in all age groups, regardless of gender and type of treatment; however, it maintained the same value for the homologous periods -Q3 to Q2. Body mass index z-score increased from -Q4/-Q3 to Q2/Q3 (0.58 standard deviation to 0.71 standard deviation, p = 0.009). Insulin daily dose increased from -Q3 to Q3 (0.87 U/kg/day to 0.91 U/kg/day, p = 0.009). Conclusion: During the lockdown period, there was no worsening of metabolic control and parents made accurate adjustments to insulin doses, indicating a good level of knowledge regarding the treatment of type 1 diabetes.Sociedade Portuguesa de Pediatria2022-10-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25754/pjp.2022.25777eng2184-44532184-3333Santos, JoanaBotelho, TeresaCaetano, Joana SerraCardoso, RitaDinis, IsabelMirante, Aliceinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T02:58:23Zoai:ojs.revistas.rcaap.pt:article/25777Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:25:40.034934Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
title COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
spellingShingle COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
Santos, Joana
Original articles
title_short COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
title_full COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
title_fullStr COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
title_full_unstemmed COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
title_sort COVID-19 Pandemic Impact on Metabolic Control of Type 1 Diabetes in Children
author Santos, Joana
author_facet Santos, Joana
Botelho, Teresa
Caetano, Joana Serra
Cardoso, Rita
Dinis, Isabel
Mirante, Alice
author_role author
author2 Botelho, Teresa
Caetano, Joana Serra
Cardoso, Rita
Dinis, Isabel
Mirante, Alice
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Santos, Joana
Botelho, Teresa
Caetano, Joana Serra
Cardoso, Rita
Dinis, Isabel
Mirante, Alice
dc.subject.por.fl_str_mv Original articles
topic Original articles
description Introduction: Coronavirus disease 2019 pandemic has led to the adoption of extreme public health measures worldwide, and many governments imposed lockdown policies during the pandemic. In Portugal, the first emergency state began in March 2020 which led to the closure of schools and gyms, depriving children of all physical activities. This study aimed to evaluate the lockdown impact on metabolic control of children with type 1 diabetes. Methods: Children with type 1 diabetes, followed in the pediatric endocrinology unit of a tertiary care hospital were included in this study. Data were collected from 16/03/2019 to 15/12/2020 and analyzed by quarters: -Q4, -Q3, -Q2, -Q1, from 16/03/2019 to 15/03/2020, and Q1, Q2, and Q3 from 16/03/2020 to 15/12/2020. Metabolic control was evaluated by evolution of glycated hemoglobin, z-score of body mass index, and the insulin daily dose. The statistical analysis was performed using SPSS Statistics (version 23), and mean differences were considered statistically significant at p < 0.05. Results: This study included a total of 203 patients with a mean age of 10.8 ± 3.2 years and a type 1 diabetes duration of 6.4 ± 3.6 years. Moreover, 57.1% of the patients were male, and 86.7% were undergoing continuous subcutaneous insulin infusion. Mean glycated hemoglobin decreased from Q1 to Q2 (7.97% to 7.51%, p < 0.001) in all age groups, regardless of gender and type of treatment; however, it maintained the same value for the homologous periods -Q3 to Q2. Body mass index z-score increased from -Q4/-Q3 to Q2/Q3 (0.58 standard deviation to 0.71 standard deviation, p = 0.009). Insulin daily dose increased from -Q3 to Q3 (0.87 U/kg/day to 0.91 U/kg/day, p = 0.009). Conclusion: During the lockdown period, there was no worsening of metabolic control and parents made accurate adjustments to insulin doses, indicating a good level of knowledge regarding the treatment of type 1 diabetes.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-03
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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