Uveitis, syphilis and AIDS

Detalhes bibliográficos
Autor(a) principal: A. Sousa, Conceição
Data de Publicação: 2000
Outros Autores: Alves, Paulo, Pinto Ferreira, A., Cocco Martins, Conceição, Vital Morgado, A.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/2010
Resumo: The authors report on a 55 year-old man,withtreated primary syphilis in his twenties.Since thenfour further episodes were described,the last one,adequately treated,two years ago.A red eye tookhim to the outpatient ophtalmologic clinic where adiagnosis of panuveitis and syphilitic roseola wasmade,and his laboratorial evaluation disclosedVenereal Disease Reseach Laboratory (VDRL)positive; Fluorescent Treponemal AntibodyAbsorbed (FTHA) Test positive; HumanImunodeficiency Virus (HIV) positive.He was admitted for cerebral spinal fluidexamination,which showed pleocitosis,increasedproteins, VDRL negative, TPHA positive, FTA-ABSpositive, compatible with syphilitic envolvement ofCentral Nervous System.Neurosyphilis diagnosis in dually infected patientswith syphilis and HIV is difficult and complex,because it is based on serological tests that don’tfollow the usual pattern.Therapy is also controversial,because there areseveral reported neurological recurrencies afterconventional treatment.A close follow up of thesepatients is recommended.
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spelling Uveitis, syphilis and AIDSUveíte, sífilis e SIDAuveítesífilisSIDAuveitissyphilisAIDSThe authors report on a 55 year-old man,withtreated primary syphilis in his twenties.Since thenfour further episodes were described,the last one,adequately treated,two years ago.A red eye tookhim to the outpatient ophtalmologic clinic where adiagnosis of panuveitis and syphilitic roseola wasmade,and his laboratorial evaluation disclosedVenereal Disease Reseach Laboratory (VDRL)positive; Fluorescent Treponemal AntibodyAbsorbed (FTHA) Test positive; HumanImunodeficiency Virus (HIV) positive.He was admitted for cerebral spinal fluidexamination,which showed pleocitosis,increasedproteins, VDRL negative, TPHA positive, FTA-ABSpositive, compatible with syphilitic envolvement ofCentral Nervous System.Neurosyphilis diagnosis in dually infected patientswith syphilis and HIV is difficult and complex,because it is based on serological tests that don’tfollow the usual pattern.Therapy is also controversial,because there areseveral reported neurological recurrencies afterconventional treatment.A close follow up of thesepatients is recommended.Os autores apresentam o caso clínico de umhomem de 55 anos com antecedentes de sífilisprimária na juventude e quatro reinfecçõesposteriores, a última das quais há dois anos,adequadamente tratada e com remissão do quadro.Observado em consulta externa de Oftalmologia,por olho vermelho, foi-lhe diagnosticada pan-uveíte,com íris de características sifilíticas (roséola sifilítica).Na sua avaliação laboratorial salientaram-se:Venereal Disease Research Laboratory (VDRL)positivo, Fluorescent Treponemal AntibodyAbsorbed Test (FTA-ABS) positivo, Vírus daImunodeficiência Humana (VIH-1) positivo.Internado no Serviço de Medicina, foi submetidoa punção lombar, tendo a análise do liquor reveladopleocitose, proteinorraquia aumentada,VDRLnegativo, Treponema Pallidum HemagglutinationAssay (TPHA) positivo e FTA/ABS positivo, aspectosestes compatíveis com envolvimento sifilítico do SNC.O diagnóstico de neurosífilis assintomática nosdoentes duplamente infectados é difícil e complexo,pois fundamenta-se em testes serológicos que nãoobedecem ao padrão habitual. A terapêutica écontroversa, devido à recorrência dos quadrosneurológicos após terapêuticas consideradasadequadas, sendo recomendada vigilância apertadadestes doentes.Sociedade Portuguesa de Medicina Interna2000-12-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spmi.pt/index.php/rpmi/article/view/2010Internal Medicine; Vol. 7 No. 4 (2000): Outubro/ Dezembro; 215-218Medicina Interna; Vol. 7 N.º 4 (2000): Outubro/ Dezembro; 215-2182183-99800872-671Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spmi.pt/index.php/rpmi/article/view/2010https://revista.spmi.pt/index.php/rpmi/article/view/2010/1408A. Sousa, ConceiçãoAlves, PauloPinto Ferreira, A.Cocco Martins, ConceiçãoVital Morgado, A.info:eu-repo/semantics/openAccess2023-06-10T06:11:10Zoai:oai.revista.spmi.pt:article/2010Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:00:08.198531Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Uveitis, syphilis and AIDS
Uveíte, sífilis e SIDA
title Uveitis, syphilis and AIDS
spellingShingle Uveitis, syphilis and AIDS
A. Sousa, Conceição
uveíte
sífilis
SIDA
uveitis
syphilis
AIDS
title_short Uveitis, syphilis and AIDS
title_full Uveitis, syphilis and AIDS
title_fullStr Uveitis, syphilis and AIDS
title_full_unstemmed Uveitis, syphilis and AIDS
title_sort Uveitis, syphilis and AIDS
author A. Sousa, Conceição
author_facet A. Sousa, Conceição
Alves, Paulo
Pinto Ferreira, A.
Cocco Martins, Conceição
Vital Morgado, A.
author_role author
author2 Alves, Paulo
Pinto Ferreira, A.
Cocco Martins, Conceição
Vital Morgado, A.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv A. Sousa, Conceição
Alves, Paulo
Pinto Ferreira, A.
Cocco Martins, Conceição
Vital Morgado, A.
dc.subject.por.fl_str_mv uveíte
sífilis
SIDA
uveitis
syphilis
AIDS
topic uveíte
sífilis
SIDA
uveitis
syphilis
AIDS
description The authors report on a 55 year-old man,withtreated primary syphilis in his twenties.Since thenfour further episodes were described,the last one,adequately treated,two years ago.A red eye tookhim to the outpatient ophtalmologic clinic where adiagnosis of panuveitis and syphilitic roseola wasmade,and his laboratorial evaluation disclosedVenereal Disease Reseach Laboratory (VDRL)positive; Fluorescent Treponemal AntibodyAbsorbed (FTHA) Test positive; HumanImunodeficiency Virus (HIV) positive.He was admitted for cerebral spinal fluidexamination,which showed pleocitosis,increasedproteins, VDRL negative, TPHA positive, FTA-ABSpositive, compatible with syphilitic envolvement ofCentral Nervous System.Neurosyphilis diagnosis in dually infected patientswith syphilis and HIV is difficult and complex,because it is based on serological tests that don’tfollow the usual pattern.Therapy is also controversial,because there areseveral reported neurological recurrencies afterconventional treatment.A close follow up of thesepatients is recommended.
publishDate 2000
dc.date.none.fl_str_mv 2000-12-29
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/2010
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dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://revista.spmi.pt/index.php/rpmi/article/view/2010
https://revista.spmi.pt/index.php/rpmi/article/view/2010/1408
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
publisher.none.fl_str_mv Sociedade Portuguesa de Medicina Interna
dc.source.none.fl_str_mv Internal Medicine; Vol. 7 No. 4 (2000): Outubro/ Dezembro; 215-218
Medicina Interna; Vol. 7 N.º 4 (2000): Outubro/ Dezembro; 215-218
2183-9980
0872-671X
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