Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies

Detalhes bibliográficos
Autor(a) principal: Alexandre, Nuno
Data de Publicação: 2014
Outros Autores: Ribeiro, Jorge, Gärtner, Andrea, Pereira, Tiago, Amorim, Irina, Fragoso, João, Lopes, Ascensão, Fernandes, João, Costa, Elísio, Santos-Silva, Alice, Rodrigues, Miguel, Santos, José Domingos, Maurício, Ana Colette, Luís, Ana Lúcia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10174/13951
Resumo: Polyvinyl alcohol hydrogel (PVA) is a synthetic polymer with an increasing application in the biomedical field that can potentially be used for vascular grafting. However, the tissue and blood–material interactions of such gels and membranesare unknown in detail. The objectives of this study were to: (a) assess the biocompatibility and (b) hemocompatibility of PVA-based membranes in order to get some insight into its potential use as a vascular graft. PVA was evaluated isolated or in copolymerization with dextran (DX), a biopolymer with known effects in blood coagulation homeostasis.
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spelling Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studiesPolyvinyl alcohol hydrogel (PVA) is a synthetic polymer with an increasing application in the biomedical field that can potentially be used for vascular grafting. However, the tissue and blood–material interactions of such gels and membranesare unknown in detail. The objectives of this study were to: (a) assess the biocompatibility and (b) hemocompatibility of PVA-based membranes in order to get some insight into its potential use as a vascular graft. PVA was evaluated isolated or in copolymerization with dextran (DX), a biopolymer with known effects in blood coagulation homeostasis.2015-03-31T21:12:38Z2015-03-312014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/13951http://hdl.handle.net/10174/13951por15493296Alexandre, Nuno; Ribeiro, Jorge; Gärtner, Andrea; Pereira, Tiago; Amorim, Irina; Fragoso, João; Lopes, Ascensão; Fernandes, João; Costa, Elísio; Santos-Silva, Alice; Rodrigues, Miguel; Santos, José Domingos; Maurício, Ana Colette; Luís, Ana Lúcia. Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies , Journal of Biomedical Materials Research Part A, 102, 12, 4262-4275, 2014.ndndndndndndndndndndndndndndAlexandre, NunoRibeiro, JorgeGärtner, AndreaPereira, TiagoAmorim, IrinaFragoso, JoãoLopes, AscensãoFernandes, JoãoCosta, ElísioSantos-Silva, AliceRodrigues, MiguelSantos, José DomingosMaurício, Ana ColetteLuís, Ana Lúciainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T18:59:53Zoai:dspace.uevora.pt:10174/13951Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:07:19.782246Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
title Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
spellingShingle Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
Alexandre, Nuno
title_short Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
title_full Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
title_fullStr Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
title_full_unstemmed Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
title_sort Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
author Alexandre, Nuno
author_facet Alexandre, Nuno
Ribeiro, Jorge
Gärtner, Andrea
Pereira, Tiago
Amorim, Irina
Fragoso, João
Lopes, Ascensão
Fernandes, João
Costa, Elísio
Santos-Silva, Alice
Rodrigues, Miguel
Santos, José Domingos
Maurício, Ana Colette
Luís, Ana Lúcia
author_role author
author2 Ribeiro, Jorge
Gärtner, Andrea
Pereira, Tiago
Amorim, Irina
Fragoso, João
Lopes, Ascensão
Fernandes, João
Costa, Elísio
Santos-Silva, Alice
Rodrigues, Miguel
Santos, José Domingos
Maurício, Ana Colette
Luís, Ana Lúcia
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Alexandre, Nuno
Ribeiro, Jorge
Gärtner, Andrea
Pereira, Tiago
Amorim, Irina
Fragoso, João
Lopes, Ascensão
Fernandes, João
Costa, Elísio
Santos-Silva, Alice
Rodrigues, Miguel
Santos, José Domingos
Maurício, Ana Colette
Luís, Ana Lúcia
description Polyvinyl alcohol hydrogel (PVA) is a synthetic polymer with an increasing application in the biomedical field that can potentially be used for vascular grafting. However, the tissue and blood–material interactions of such gels and membranesare unknown in detail. The objectives of this study were to: (a) assess the biocompatibility and (b) hemocompatibility of PVA-based membranes in order to get some insight into its potential use as a vascular graft. PVA was evaluated isolated or in copolymerization with dextran (DX), a biopolymer with known effects in blood coagulation homeostasis.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01T00:00:00Z
2015-03-31T21:12:38Z
2015-03-31
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10174/13951
http://hdl.handle.net/10174/13951
url http://hdl.handle.net/10174/13951
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 15493296
Alexandre, Nuno; Ribeiro, Jorge; Gärtner, Andrea; Pereira, Tiago; Amorim, Irina; Fragoso, João; Lopes, Ascensão; Fernandes, João; Costa, Elísio; Santos-Silva, Alice; Rodrigues, Miguel; Santos, José Domingos; Maurício, Ana Colette; Luís, Ana Lúcia. Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies , Journal of Biomedical Materials Research Part A, 102, 12, 4262-4275, 2014.
nd
nd
nd
nd
nd
nd
nd
nd
nd
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nd
nd
nd
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eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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