Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles
Autor(a) principal: | |
---|---|
Data de Publicação: | 2013 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/31108 |
Resumo: | In recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health-care field. |
id |
RCAP_b9d00fe10dfc5811dda1498299117830 |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/31108 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textilesAlginateChitosanCottonJIS L 1902LbLScience & TechnologyIn recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health-care field.The authors would like to thank Fundacao para a Ciencia e Tecnologia (FCT) for the funding granted concerning the project - PTDC/EBB-BIO/113671/2009 (FCOMP-01-0124-FEDER-014752) Skin2Tex. Also, we would like to thank Fundo Europeu de Desenvolvimento Regional (FEDER) through COMPETE - Programa Operacional Factores de Competitividade (POFC) for the co-funding.John Wiley and SonsUniversidade do MinhoGomes, Ana P.Mano, J. F.Queiroz, J. A.Gouveia, I. C.2013-102013-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/31108eng1099-1581 (online)10.1002/pat.3176http://onlinelibrary.wiley.com/doi/10.1002/pat.3176/abstractinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:52:37Zoai:repositorium.sdum.uminho.pt:1822/31108Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:51:47.382184Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles |
title |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles |
spellingShingle |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles Gomes, Ana P. Alginate Chitosan Cotton JIS L 1902 LbL Science & Technology |
title_short |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles |
title_full |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles |
title_fullStr |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles |
title_full_unstemmed |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles |
title_sort |
Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles |
author |
Gomes, Ana P. |
author_facet |
Gomes, Ana P. Mano, J. F. Queiroz, J. A. Gouveia, I. C. |
author_role |
author |
author2 |
Mano, J. F. Queiroz, J. A. Gouveia, I. C. |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Gomes, Ana P. Mano, J. F. Queiroz, J. A. Gouveia, I. C. |
dc.subject.por.fl_str_mv |
Alginate Chitosan Cotton JIS L 1902 LbL Science & Technology |
topic |
Alginate Chitosan Cotton JIS L 1902 LbL Science & Technology |
description |
In recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health-care field. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-10 2013-10-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/31108 |
url |
http://hdl.handle.net/1822/31108 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1099-1581 (online) 10.1002/pat.3176 http://onlinelibrary.wiley.com/doi/10.1002/pat.3176/abstract |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
John Wiley and Sons |
publisher.none.fl_str_mv |
John Wiley and Sons |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133107720290304 |