Obesity and infection - the challenge of tropical medicine
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/33145 https://doi.org/10.19277/bbr.13.1.132 |
Resumo: | The World Health Organization currently considers obesity a worldwide epidemic. A perspective of the past considered overeating and a sedentary lifestyle as main factors of this major public health problem. However, other risk factors can be associated, such as heredity, sleep disorders and the action of microbial agents. Regarding the association of obesity with infection, it appears that some microorganisms such as viruses, bacteria, parasites and tropical microbial agents (e.g. chagas disease and cutaneous leishmaniasis) are markedly related to human obesity, and it has been shown that obese individuals have an altered response to infections. The mechanism behind the adipogenic action of these microorganisms varies from the effect on the central nervous system, to the modification of metabolism of adipose tissue. Obesity and the consequent expansion of adipose tissue alter imune system function, which may lead to an increased susceptibility to infection by various microorganisms. In summary, there is a close interrelationship between the adipose tissue, the immune-inflammatory response and infection, being conceivable that in response to certain infections, adipose tissue expands and reacts in a similar way to the expansion of immune system cells. Obesity decreases the immune response of adipose tissue, which modifies the patocronia of infections. |
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Obesity and infection - the challenge of tropical medicineObesidade e infeção - o desafio da medicina tropicalObesity/ObesidadeInfection/InfeçãoThe World Health Organization currently considers obesity a worldwide epidemic. A perspective of the past considered overeating and a sedentary lifestyle as main factors of this major public health problem. However, other risk factors can be associated, such as heredity, sleep disorders and the action of microbial agents. Regarding the association of obesity with infection, it appears that some microorganisms such as viruses, bacteria, parasites and tropical microbial agents (e.g. chagas disease and cutaneous leishmaniasis) are markedly related to human obesity, and it has been shown that obese individuals have an altered response to infections. The mechanism behind the adipogenic action of these microorganisms varies from the effect on the central nervous system, to the modification of metabolism of adipose tissue. Obesity and the consequent expansion of adipose tissue alter imune system function, which may lead to an increased susceptibility to infection by various microorganisms. In summary, there is a close interrelationship between the adipose tissue, the immune-inflammatory response and infection, being conceivable that in response to certain infections, adipose tissue expands and reacts in a similar way to the expansion of immune system cells. Obesity decreases the immune response of adipose tissue, which modifies the patocronia of infections.ALIES - the Lusophone Association for the Development of Teaching and Research in Health Sciences2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/33145http://hdl.handle.net/10316/33145https://doi.org/10.19277/bbr.13.1.132enghttp://www.alies.pt/index.php/en/bbr/archiveMota Pinto, Anabelainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2021-08-18T09:39:09Zoai:estudogeral.uc.pt:10316/33145Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:43:25.594965Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Obesity and infection - the challenge of tropical medicine Obesidade e infeção - o desafio da medicina tropical |
title |
Obesity and infection - the challenge of tropical medicine |
spellingShingle |
Obesity and infection - the challenge of tropical medicine Mota Pinto, Anabela Obesity/Obesidade Infection/Infeção |
title_short |
Obesity and infection - the challenge of tropical medicine |
title_full |
Obesity and infection - the challenge of tropical medicine |
title_fullStr |
Obesity and infection - the challenge of tropical medicine |
title_full_unstemmed |
Obesity and infection - the challenge of tropical medicine |
title_sort |
Obesity and infection - the challenge of tropical medicine |
author |
Mota Pinto, Anabela |
author_facet |
Mota Pinto, Anabela |
author_role |
author |
dc.contributor.author.fl_str_mv |
Mota Pinto, Anabela |
dc.subject.por.fl_str_mv |
Obesity/Obesidade Infection/Infeção |
topic |
Obesity/Obesidade Infection/Infeção |
description |
The World Health Organization currently considers obesity a worldwide epidemic. A perspective of the past considered overeating and a sedentary lifestyle as main factors of this major public health problem. However, other risk factors can be associated, such as heredity, sleep disorders and the action of microbial agents. Regarding the association of obesity with infection, it appears that some microorganisms such as viruses, bacteria, parasites and tropical microbial agents (e.g. chagas disease and cutaneous leishmaniasis) are markedly related to human obesity, and it has been shown that obese individuals have an altered response to infections. The mechanism behind the adipogenic action of these microorganisms varies from the effect on the central nervous system, to the modification of metabolism of adipose tissue. Obesity and the consequent expansion of adipose tissue alter imune system function, which may lead to an increased susceptibility to infection by various microorganisms. In summary, there is a close interrelationship between the adipose tissue, the immune-inflammatory response and infection, being conceivable that in response to certain infections, adipose tissue expands and reacts in a similar way to the expansion of immune system cells. Obesity decreases the immune response of adipose tissue, which modifies the patocronia of infections. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/33145 http://hdl.handle.net/10316/33145 https://doi.org/10.19277/bbr.13.1.132 |
url |
http://hdl.handle.net/10316/33145 https://doi.org/10.19277/bbr.13.1.132 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://www.alies.pt/index.php/en/bbr/archive |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
ALIES - the Lusophone Association for the Development of Teaching and Research in Health Sciences |
publisher.none.fl_str_mv |
ALIES - the Lusophone Association for the Development of Teaching and Research in Health Sciences |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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|
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1799133706571481088 |