Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/105357 https://doi.org/10.3390/plants10050846 |
Resumo: | Valerianaceae, the sub-family of Caprifoliaceae, contains more than 300 species of annual and perennial herbs, worldwide distributed. Several species are used for their biological properties while some are used as food. Species from the genus Valeriana have been used for their antispasmodic, relaxing, and sedative properties, which have been mainly attributed to the presence of valepotriates, borneol derivatives, and isovalerenic acid. Among this genus, the most common and employed species is Valerianaofficinalis. Although valerian has been traditionally used as a mild sedative, research results are still controversial regarding the role of the different active compounds, the herbal preparations, and the dosage used. The present review is designed to summarize and critically describe the current knowledge on the different plant species belonging to Valerianaceae, their phytochemicals, their uses in the treatment of different diseases with particular emphasis on the effects on the central nervous system. The available information on this sub-family was collected from scientific databases up until year 2020. The following electronic databases were used: PubMed, Scopus, Sci Finder, Web of Science, Science Direct, NCBI, and Google Scholar. The search terms used for this review included Valerianaceae, Valeriana, Centranthus, Fedia, Patrinia, Nardostachys, Plectritis, and Valerianella, phytochemical composition, in vivo studies, Central Nervous System, neuroprotective, antidepressant, antinociceptive, anxiolytic, anxiety, preclinical and clinical studies. |
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Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous SystemValerianaceaeanxiolyticsedativemyorelaxantantidepressantbiological activitiesclinical studiesphytochemicalsvalerianValerianaceae, the sub-family of Caprifoliaceae, contains more than 300 species of annual and perennial herbs, worldwide distributed. Several species are used for their biological properties while some are used as food. Species from the genus Valeriana have been used for their antispasmodic, relaxing, and sedative properties, which have been mainly attributed to the presence of valepotriates, borneol derivatives, and isovalerenic acid. Among this genus, the most common and employed species is Valerianaofficinalis. Although valerian has been traditionally used as a mild sedative, research results are still controversial regarding the role of the different active compounds, the herbal preparations, and the dosage used. The present review is designed to summarize and critically describe the current knowledge on the different plant species belonging to Valerianaceae, their phytochemicals, their uses in the treatment of different diseases with particular emphasis on the effects on the central nervous system. The available information on this sub-family was collected from scientific databases up until year 2020. The following electronic databases were used: PubMed, Scopus, Sci Finder, Web of Science, Science Direct, NCBI, and Google Scholar. The search terms used for this review included Valerianaceae, Valeriana, Centranthus, Fedia, Patrinia, Nardostachys, Plectritis, and Valerianella, phytochemical composition, in vivo studies, Central Nervous System, neuroprotective, antidepressant, antinociceptive, anxiolytic, anxiety, preclinical and clinical studies.MDPI2021-04-22info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/105357http://hdl.handle.net/10316/105357https://doi.org/10.3390/plants10050846eng2223-7747Das, GitishreeShin, Han-SeungTundis, RosaGonçalves, SandraTantengco, Ourlad Alzeus G.Campos, Maria G.Acquaviva, RosariaMalfa, Giuseppe AntonioRomano, AnabelaRobles, Joyce Ann H.Clores, Mariel Q.Patra, Jayanta-Kumarinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-02-20T10:40:34Zoai:estudogeral.uc.pt:10316/105357Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:21:56.899972Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System |
title |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System |
spellingShingle |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System Das, Gitishree Valerianaceae anxiolytic sedative myorelaxant antidepressant biological activities clinical studies phytochemicals valerian |
title_short |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System |
title_full |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System |
title_fullStr |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System |
title_full_unstemmed |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System |
title_sort |
Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System |
author |
Das, Gitishree |
author_facet |
Das, Gitishree Shin, Han-Seung Tundis, Rosa Gonçalves, Sandra Tantengco, Ourlad Alzeus G. Campos, Maria G. Acquaviva, Rosaria Malfa, Giuseppe Antonio Romano, Anabela Robles, Joyce Ann H. Clores, Mariel Q. Patra, Jayanta-Kumar |
author_role |
author |
author2 |
Shin, Han-Seung Tundis, Rosa Gonçalves, Sandra Tantengco, Ourlad Alzeus G. Campos, Maria G. Acquaviva, Rosaria Malfa, Giuseppe Antonio Romano, Anabela Robles, Joyce Ann H. Clores, Mariel Q. Patra, Jayanta-Kumar |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Das, Gitishree Shin, Han-Seung Tundis, Rosa Gonçalves, Sandra Tantengco, Ourlad Alzeus G. Campos, Maria G. Acquaviva, Rosaria Malfa, Giuseppe Antonio Romano, Anabela Robles, Joyce Ann H. Clores, Mariel Q. Patra, Jayanta-Kumar |
dc.subject.por.fl_str_mv |
Valerianaceae anxiolytic sedative myorelaxant antidepressant biological activities clinical studies phytochemicals valerian |
topic |
Valerianaceae anxiolytic sedative myorelaxant antidepressant biological activities clinical studies phytochemicals valerian |
description |
Valerianaceae, the sub-family of Caprifoliaceae, contains more than 300 species of annual and perennial herbs, worldwide distributed. Several species are used for their biological properties while some are used as food. Species from the genus Valeriana have been used for their antispasmodic, relaxing, and sedative properties, which have been mainly attributed to the presence of valepotriates, borneol derivatives, and isovalerenic acid. Among this genus, the most common and employed species is Valerianaofficinalis. Although valerian has been traditionally used as a mild sedative, research results are still controversial regarding the role of the different active compounds, the herbal preparations, and the dosage used. The present review is designed to summarize and critically describe the current knowledge on the different plant species belonging to Valerianaceae, their phytochemicals, their uses in the treatment of different diseases with particular emphasis on the effects on the central nervous system. The available information on this sub-family was collected from scientific databases up until year 2020. The following electronic databases were used: PubMed, Scopus, Sci Finder, Web of Science, Science Direct, NCBI, and Google Scholar. The search terms used for this review included Valerianaceae, Valeriana, Centranthus, Fedia, Patrinia, Nardostachys, Plectritis, and Valerianella, phytochemical composition, in vivo studies, Central Nervous System, neuroprotective, antidepressant, antinociceptive, anxiolytic, anxiety, preclinical and clinical studies. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-04-22 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/105357 http://hdl.handle.net/10316/105357 https://doi.org/10.3390/plants10050846 |
url |
http://hdl.handle.net/10316/105357 https://doi.org/10.3390/plants10050846 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2223-7747 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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