Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets

Detalhes bibliográficos
Autor(a) principal: Madeira, Marta Sofia Morgado dos Santos
Data de Publicação: 2021
Outros Autores: Lopes, Paula Alexandra Antunes Brás, Martins, Cátia Falcão, Assunção, José Miguel Pestana, Alfaia, Cristina Maria Riscado Pereira Mateus, Pinto, Rui Manuel Amaro, Prates, José António Mestre
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.5/21391
Resumo: Research Article
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spelling Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned pigletsArthrospira platensisenzymesantioxidant potentialhepatic lipid metabolismpigletsResearch ArticleBackground: The ability of a high level of dietary Arthrospira platensis, individually or in combination with two exogenous carbohydrate-degrading enzymes (lysozyme and Rovabio®), to improve systemic antioxidant potential and hepatic lipid metabolism was tested in piglets. Forty male post-weaned piglets, sons of Large White × Landrace sows crossed with Pietrain boars, were allocated into 4 groups (n = 10) and fed during 28 days one of the following diets: 1) a control basal diet (cereal and soybean meal); 2) a basal diet with 10% of A. platensis (AP); 3) the AP diet supplemented with 0.005% of Rovabio® (AP + R); 4) the AP diet supplemented with 0.01% of lysozyme (AP + L). Results: Arthrospira platensis decreased BW gain of piglets, regardless the addition of feed enzymes. The majority of plasma metabolites were affected by diets. A. platensis increased total lipids, total cholesterol and LDL-cholesterol, without changing hepatic fatty acid content or modulating, in an expressive manner, the transcriptional profile of lipid sensitive mediators. The antioxidant potential in general, and total carotenoids in particular, were improved by the microalga, regardless lysozyme or Rovabio®. Conclusions: Summing up, A. platensis, individually and combined with feed enzymes, impacts negatively on piglets’ growth but improves the systemic antioxidant potential and changes plasma lipids with a minor modulation on related hepatic metabolic pathwaysBMCRepositório da Universidade de LisboaMadeira, Marta Sofia Morgado dos SantosLopes, Paula Alexandra Antunes BrásMartins, Cátia FalcãoAssunção, José Miguel PestanaAlfaia, Cristina Maria Riscado Pereira MateusPinto, Rui Manuel AmaroPrates, José António Mestre2021-05-31T13:28:24Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/21391engSantos Madeira et al. BMC Veterinary Research (2021) 17:158https://doi.org/10.1186/s12917-021-02869-yinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-06T14:50:50Zoai:www.repository.utl.pt:10400.5/21391Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:05:59.248366Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
title Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
spellingShingle Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
Madeira, Marta Sofia Morgado dos Santos
Arthrospira platensis
enzymes
antioxidant potential
hepatic lipid metabolism
piglets
title_short Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
title_full Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
title_fullStr Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
title_full_unstemmed Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
title_sort Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets
author Madeira, Marta Sofia Morgado dos Santos
author_facet Madeira, Marta Sofia Morgado dos Santos
Lopes, Paula Alexandra Antunes Brás
Martins, Cátia Falcão
Assunção, José Miguel Pestana
Alfaia, Cristina Maria Riscado Pereira Mateus
Pinto, Rui Manuel Amaro
Prates, José António Mestre
author_role author
author2 Lopes, Paula Alexandra Antunes Brás
Martins, Cátia Falcão
Assunção, José Miguel Pestana
Alfaia, Cristina Maria Riscado Pereira Mateus
Pinto, Rui Manuel Amaro
Prates, José António Mestre
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Madeira, Marta Sofia Morgado dos Santos
Lopes, Paula Alexandra Antunes Brás
Martins, Cátia Falcão
Assunção, José Miguel Pestana
Alfaia, Cristina Maria Riscado Pereira Mateus
Pinto, Rui Manuel Amaro
Prates, José António Mestre
dc.subject.por.fl_str_mv Arthrospira platensis
enzymes
antioxidant potential
hepatic lipid metabolism
piglets
topic Arthrospira platensis
enzymes
antioxidant potential
hepatic lipid metabolism
piglets
description Research Article
publishDate 2021
dc.date.none.fl_str_mv 2021-05-31T13:28:24Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/21391
url http://hdl.handle.net/10400.5/21391
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Santos Madeira et al. BMC Veterinary Research (2021) 17:158
https://doi.org/10.1186/s12917-021-02869-y
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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